Is Pixi a NSAID?

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pixi?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Pixi be used along with dexamethasone?

No. Pixi should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Can I use Pixi if I have peptic ulcer disease?

No. Pixi is contraindicated in cases of active peptic ulcer disease. Pixi is known to cause gastric ulceration and bleeding.

Can I use Pixi if I am pregnant?

No. Pixi should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can I use Pixi if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Is Pixi affective in gout management?

Yes. Pixi can be given for the treatment of acute gout. Research studies have shown Pixi to be highly effective in the treatment of acute gout.

Can Pixi be used with calcium channel blocker?

Yes. Pixi can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Can I use Pixi if I am a diabetic?

Pixi in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pixi so taking piroxicam can lead to increased risk of renal failure by many folds.

Is Pixi a blood thinner?

No. Pixi is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can Pixi be used along with paracetamol?

Yes. Paracetamol can be used with Pixi as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Pixi a narcotic?

No. Pixi is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Is Pixi a muscle relaxant?

No. Pixi is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Pixi lead to skin reactions?

Yes. Pixi is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Can Pixi be used with methocarbamol?

Yes. Methocarbamol can be used with Pixi as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Pixi be used with Tizanidine?

Yes, Pixi can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can Pixi lead to difficulty in conception?

Yes. Pixi can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can you donate blood when on the medication with Pixi?

Yes. You can donate blood when on Pixi. Do inform your doctor before donating blood.

Can Pixi be used to treat menstrual cramp?

Pixi is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Why is beta cyclodextrin added to Pixi?

Yes. Pixi can be combined with beta-cyclodextrin. Research has shown that combining Pixi with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can Pixi be used in the treatment of allergy?

No. Pixi is not a drug to treat allergy. It is a pain killer.

Is Pixi a sulfa drug?

Pixi is a sulphur containing compound. Pixi can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

What increases the chances of getting a gastric ulcer when I am already taking Pixi?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

What is the difference between Pixi and nimesulide?

Both Pixi and nimesulide are pain killers. However, Pixi is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Can you get high by using Pixi?

No. Pixi is not known to cause high. It is a non-narcotic painkiller.

What are the contraindications for Pixi?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

What is the difference between Pixi and tramadol?

Pixi is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Are Pixi and aspirin same?

No. Pixi and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

How long does Pixi work?

Pixi is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can Pixi be used with warfarin?

No. Pixi should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

What is the difference between Pixi and meloxicam?

Both Pixi and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Pixi.