Is Piroxone affective in gout management?

Can Piroxone be used with calcium channel blocker?

Yes. Piroxone can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

What is the difference between Piroxone and meloxicam?

Both Piroxone and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Piroxone.

Can you donate blood when on the medication with Piroxone?

Yes. You can donate blood when on Piroxone. Do inform your doctor before donating blood.

Can Piroxone lead to difficulty in conception?

Yes. Piroxone can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can Piroxone be used along with paracetamol?

Yes. Paracetamol can be used with Piroxone as no serious side effects are known. Inform your doctor before starting any of the medication.

What is the difference between Piroxone and nimesulide?

Both Piroxone and nimesulide are pain killers. However, Piroxone is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Is Piroxone a muscle relaxant?

No. Piroxone is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Is Piroxone a blood thinner?

No. Piroxone is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Are there any alternatives of Piroxone?

Yes. There are alternatives to Piroxone. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Is Piroxone a NSAID?

Yes. Piroxone is a non-steroidal anti-inflammatory drug (NSAID).

What is the difference between Piroxone and diclofenac?

Both Piroxone and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Piroxone.

Can Piroxone be used with methocarbamol?

Yes. Methocarbamol can be used with Piroxone as no serious side effects are known. Inform your doctor before starting any of the medication.

What is the difference between Piroxone and ketoprofen?

Both Piroxone and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Piroxone. Ketoprofen gel also showed excellent tolerability.

Are Piroxone and aspirin same?

No. Piroxone and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Can Piroxone be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Piroxone or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Piroxone.

What is the difference between Piroxone and naproxen?

Both Piroxone and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Piroxone.

How long does Piroxone work?

Piroxone is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can Piroxone be used in hypertension?

No. Piroxone is not a medication to control hypertension. It is important to note that Piroxone decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Piroxone.

Can Piroxone be used to treat menstrual cramp?

Piroxone is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Can I use Piroxone if I have peptic ulcer disease?

No. Piroxone is contraindicated in cases of active peptic ulcer disease. Piroxone is known to cause gastric ulceration and bleeding.

Can Piroxone be used with Tizanidine?

Yes, Piroxone can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can Piroxone be used in the treatment of allergy?

No. Piroxone is not a drug to treat allergy. It is a pain killer.

Can you get high by using Piroxone?

No. Piroxone is not known to cause high. It is a non-narcotic painkiller.

Can Piroxone be used with diuretics?

No. Piroxone should not be used with diuretics. Piroxone reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Can I use Piroxone for a migraine?

Piroxone is not approved for the treatment of migraine. Research studies have shown that Piroxone is effective in significantly decreasing the pain associated with migraine without aura.

Can Piroxone be used with lithium?

No. Piroxone should not be used with lithium. Piroxone leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Can I use Piroxone if I have a deranged renal function?

No. Piroxone should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

What increases the chances of getting a gastric ulcer when I am already taking Piroxone?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Can Piroxone be used with warfarin?

No. Piroxone should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

What are the serious side effects of Piroxone?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can Piroxone be used along with dexamethasone?

No. Piroxone should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

What is the difference between Piroxone and tramadol?

Piroxone is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.