Is Pirolin affective in gout management?

What are the serious side effects of Pirolin?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can you get high by using Pirolin?

No. Pirolin is not known to cause high. It is a non-narcotic painkiller.

What is the difference between Pirolin and tramadol?

Pirolin is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Are there any alternatives of Pirolin?

Yes. There are alternatives to Pirolin. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

What is the difference between Pirolin and naproxen?

Both Pirolin and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Pirolin.

What is the difference between Pirolin and nimesulide?

Both Pirolin and nimesulide are pain killers. However, Pirolin is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Can Pirolin be used with Tizanidine?

Yes, Pirolin can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can Pirolin be used along with dexamethasone?

No. Pirolin should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Can Pirolin be used along with paracetamol?

Yes. Paracetamol can be used with Pirolin as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Pirolin a NSAID?

Yes. Pirolin is a non-steroidal anti-inflammatory drug (NSAID).

Is Pirolin a sulfa drug?

Pirolin is a sulphur containing compound. Pirolin can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Can Pirolin be used with methocarbamol?

Yes. Methocarbamol can be used with Pirolin as no serious side effects are known. Inform your doctor before starting any of the medication.

Why is beta cyclodextrin added to Pirolin?

Yes. Pirolin can be combined with beta-cyclodextrin. Research has shown that combining Pirolin with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Is Pirolin a narcotic?

No. Pirolin is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Is Pirolin a blood thinner?

No. Pirolin is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Is Pirolin a muscle relaxant?

No. Pirolin is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Pirolin be used in the treatment of allergy?

No. Pirolin is not a drug to treat allergy. It is a pain killer.

How long does Pirolin work?

Pirolin is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can you donate blood when on the medication with Pirolin?

Yes. You can donate blood when on Pirolin. Do inform your doctor before donating blood.

Can Pirolin lead to skin reactions?

Yes. Pirolin is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

What increases the chances of getting a gastric ulcer when I am already taking Pirolin?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Can I use Pirolin if I am pregnant?

No. Pirolin should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can I use Pirolin if I have a deranged renal function?

No. Pirolin should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

What are the contraindications for Pirolin?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Can I use Pirolin if I am a diabetic?

Pirolin in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pirolin so taking piroxicam can lead to increased risk of renal failure by many folds.

Can Pirolin be used with warfarin?

No. Pirolin should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Can I use Pirolin if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pirolin?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Pirolin be used with diuretics?

No. Pirolin should not be used with diuretics. Pirolin reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Are Pirolin and aspirin same?

No. Pirolin and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.