Is Piaa affective in gout management?

How long does Piaa work?

Piaa is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Are Piaa and aspirin same?

No. Piaa and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Is Piaa a NSAID?

Yes. Piaa is a non-steroidal anti-inflammatory drug (NSAID).

Is Piaa a narcotic?

No. Piaa is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Piaa be used with Lisinopril?

No. Piaa should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piaa.

Why is beta cyclodextrin added to Piaa?

Yes. Piaa can be combined with beta-cyclodextrin. Research has shown that combining Piaa with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can Piaa be used along with dexamethasone?

No. Piaa should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Can Piaa be used with calcium channel blocker?

Yes. Piaa can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Is Piaa a blood thinner?

No. Piaa is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can Piaa lead to skin reactions?

Yes. Piaa is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Can I use Piaa if I am a diabetic?

Piaa in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Piaa so taking piroxicam can lead to increased risk of renal failure by many folds.

Is Piaa a muscle relaxant?

No. Piaa is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Piaa be used with Tizanidine?

Yes, Piaa can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Is Piaa a sulfa drug?

Piaa is a sulphur containing compound. Piaa can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Can you get high by using Piaa?

No. Piaa is not known to cause high. It is a non-narcotic painkiller.

Can I use Piaa if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can you donate blood when on the medication with Piaa?

Yes. You can donate blood when on Piaa. Do inform your doctor before donating blood.

What are the serious side effects of Piaa?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

What are the contraindications for Piaa?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

What is the difference between Piaa and tramadol?

Piaa is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Piaa?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can I use Piaa if I am pregnant?

No. Piaa should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can Piaa be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Piaa or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Piaa.

Can Piaa be used with methocarbamol?

Yes. Methocarbamol can be used with Piaa as no serious side effects are known. Inform your doctor before starting any of the medication.

What is the difference between Piaa and meloxicam?

Both Piaa and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Piaa.

What increases the chances of getting a gastric ulcer when I am already taking Piaa?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

What is the difference between Piaa and naproxen?

Both Piaa and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Piaa.

Can Piaa lead to difficulty in conception?

Yes. Piaa can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

What is the difference between Piaa and ketoprofen?

Both Piaa and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Piaa. Ketoprofen gel also showed excellent tolerability.

Can Piaa be used along with paracetamol?

Yes. Paracetamol can be used with Piaa as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Piaa be used to treat menstrual cramp?

Piaa is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.