Is Paxifen a NSAID?

Can you get high by using Paxifen?

No. Paxifen is not known to cause high. It is a non-narcotic painkiller.

What increases the chances of getting a gastric ulcer when I am already taking Paxifen?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

What is the difference between Paxifen and nimesulide?

Both Paxifen and nimesulide are pain killers. However, Paxifen is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Can Paxifen lead to difficulty in conception?

Yes. Paxifen can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can Paxifen be used with methocarbamol?

Yes. Methocarbamol can be used with Paxifen as no serious side effects are known. Inform your doctor before starting any of the medication.

How long does Paxifen work?

Paxifen is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Are there any alternatives of Paxifen?

Yes. There are alternatives to Paxifen. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Can I use Paxifen for a migraine?

Paxifen is not approved for the treatment of migraine. Research studies have shown that Paxifen is effective in significantly decreasing the pain associated with migraine without aura.

Why is beta cyclodextrin added to Paxifen?

Yes. Paxifen can be combined with beta-cyclodextrin. Research has shown that combining Paxifen with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can Paxifen lead to skin reactions?

Yes. Paxifen is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

Are Paxifen and aspirin same?

No. Paxifen and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

What is the difference between Paxifen and meloxicam?

Both Paxifen and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Paxifen.

What is the difference between Paxifen and naproxen?

Both Paxifen and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Paxifen.

Can Paxifen be used with Tizanidine?

Yes, Paxifen can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Is Paxifen a blood thinner?

No. Paxifen is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Is Paxifen a muscle relaxant?

No. Paxifen is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can I use Paxifen if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can Paxifen be used with lithium?

No. Paxifen should not be used with lithium. Paxifen leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Is Paxifen a sulfa drug?

Paxifen is a sulphur containing compound. Paxifen can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Paxifen?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Paxifen be used in the treatment of allergy?

No. Paxifen is not a drug to treat allergy. It is a pain killer.

Can Paxifen be used along with paracetamol?

Yes. Paracetamol can be used with Paxifen as no serious side effects are known. Inform your doctor before starting any of the medication.

What are the serious side effects of Paxifen?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can I use Paxifen if I am a diabetic?

Paxifen in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Paxifen so taking piroxicam can lead to increased risk of renal failure by many folds.

Can I use Paxifen if I am pregnant?

No. Paxifen should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Is Paxifen a narcotic?

No. Paxifen is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Paxifen be used with warfarin?

No. Paxifen should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Can Paxifen be used along with Losartan?

No. Paxifen should not be combined with Losartan. It is important to note that Paxifen decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Paxifen.

What are the contraindications for Paxifen?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.