Is Oxi a NSAID?

Can I use Oxi if I have peptic ulcer disease?

No. Oxi is contraindicated in cases of active peptic ulcer disease. Oxi is known to cause gastric ulceration and bleeding.

Can Oxi be used with Lisinopril?

No. Oxi should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Oxi.

Can Oxi be used along with paracetamol?

Yes. Paracetamol can be used with Oxi as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Oxi be used along with dexamethasone?

No. Oxi should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Can Oxi be used in the treatment of allergy?

No. Oxi is not a drug to treat allergy. It is a pain killer.

What are the serious side effects of Oxi?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can you donate blood when on the medication with Oxi?

Yes. You can donate blood when on Oxi. Do inform your doctor before donating blood.

Is Oxi a narcotic?

No. Oxi is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

What is the difference between Oxi and meloxicam?

Both Oxi and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Oxi.

Can Oxi be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Oxi or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Oxi.

Can Oxi be used with Tizanidine?

Yes, Oxi can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can Oxi be used with calcium channel blocker?

Yes. Oxi can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Is Oxi a blood thinner?

No. Oxi is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

What is the difference between Oxi and naproxen?

Both Oxi and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Oxi.

Can you get high by using Oxi?

No. Oxi is not known to cause high. It is a non-narcotic painkiller.

Can I use Oxi if I am pregnant?

No. Oxi should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can Oxi lead to difficulty in conception?

Yes. Oxi can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can Oxi be used in hypertension?

No. Oxi is not a medication to control hypertension. It is important to note that Oxi decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Oxi.

What is the difference between Oxi and nimesulide?

Both Oxi and nimesulide are pain killers. However, Oxi is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Are Oxi and aspirin same?

No. Oxi and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Can Oxi be used with diuretics?

No. Oxi should not be used with diuretics. Oxi reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Can I use Oxi if I am a diabetic?

Oxi in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Oxi so taking piroxicam can lead to increased risk of renal failure by many folds.

Why is beta cyclodextrin added to Oxi?

Yes. Oxi can be combined with beta-cyclodextrin. Research has shown that combining Oxi with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can Oxi be used to treat menstrual cramp?

Oxi is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

How long does Oxi work?

Oxi is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can Oxi be used with warfarin?

No. Oxi should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

What increases the chances of getting a gastric ulcer when I am already taking Oxi?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Oxi?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Oxi be used with methocarbamol?

Yes. Methocarbamol can be used with Oxi as no serious side effects are known. Inform your doctor before starting any of the medication.