Is Doloforce affective in gout management?

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Doloforce?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Doloforce be used along with dexamethasone?

No. Doloforce should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Can Doloforce be used with calcium channel blocker?

Yes. Doloforce can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

What are the contraindications for Doloforce?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

What is the difference between Doloforce and ketoprofen?

Both Doloforce and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Doloforce. Ketoprofen gel also showed excellent tolerability.

What are the serious side effects of Doloforce?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can Doloforce be used in the treatment of allergy?

No. Doloforce is not a drug to treat allergy. It is a pain killer.

Can Doloforce be used with warfarin?

No. Doloforce should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

What is the difference between Doloforce and naproxen?

Both Doloforce and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Doloforce.

Can Doloforce be used in hypertension?

No. Doloforce is not a medication to control hypertension. It is important to note that Doloforce decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Doloforce.

Can you donate blood when on the medication with Doloforce?

Yes. You can donate blood when on Doloforce. Do inform your doctor before donating blood.

What is the difference between Doloforce and meloxicam?

Both Doloforce and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Doloforce.

Can I use Doloforce if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Are Doloforce and aspirin same?

No. Doloforce and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Is Doloforce a NSAID?

Yes. Doloforce is a non-steroidal anti-inflammatory drug (NSAID).

Is Doloforce a blood thinner?

No. Doloforce is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can Doloforce be used with methocarbamol?

Yes. Methocarbamol can be used with Doloforce as no serious side effects are known. Inform your doctor before starting any of the medication.

What is the difference between Doloforce and tramadol?

Doloforce is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Can I use Doloforce if I am pregnant?

No. Doloforce should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can Doloforce lead to difficulty in conception?

Yes. Doloforce can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Are there any alternatives of Doloforce?

Yes. There are alternatives to Doloforce. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Can you get high by using Doloforce?

No. Doloforce is not known to cause high. It is a non-narcotic painkiller.

Is Doloforce a muscle relaxant?

No. Doloforce is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Doloforce be used along with Losartan?

No. Doloforce should not be combined with Losartan. It is important to note that Doloforce decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloforce.

What is the difference between Doloforce and nimesulide?

Both Doloforce and nimesulide are pain killers. However, Doloforce is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

Can I use Doloforce for a migraine?

Doloforce is not approved for the treatment of migraine. Research studies have shown that Doloforce is effective in significantly decreasing the pain associated with migraine without aura.

How long does Doloforce work?

Doloforce is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can I use Doloforce if I am a diabetic?

Doloforce in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Doloforce so taking piroxicam can lead to increased risk of renal failure by many folds.

Can Doloforce be used with lithium?

No. Doloforce should not be used with lithium. Doloforce leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.