
How does Azop work?
Nov 3, 2023
How does Azop work?
Azop functions by eliminating both the larval and adult stages of the worm It achieves this by obstructing tubulin polymerization a crucial process for the worms survival This interference leads to a depletion of energy within the worm resulting in a significant decrease in its mobility As a consequence the helminth is unable to carry out essential tasks necessary for its survival Eventually this immobilization effect proves fatal for the parasite ultimately leading to its demise The mechanism of action of Azop revolves around disrupting the tubulin polymerization process Tubulin is a protein essential for the worms cellular structure and function By inhibiting its polymerization Azop disrupts the proper formation and stability of microtubules which are vital for various cellular processes in the worms body As a result the worms energy reserves are depleted impairing its ability to perform crucial tasks such as nutrient absorption and reproduction The diminished mobility caused by Azops interference with tubulin polymerization effectively renders the worm helpless Without the capability to move efficiently the helminth loses its ability to access essential resources for its survival and reproduction Ultimately the cumulative effects of Azop on the worms energy levels and mobility culminate in the demise of the parasite effectively eradicating it from the host organism
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