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How does AL 27 work?
Nov 3, 2023
How does AL 27 work?
AL 27 is a powerful compound that effectively eliminates both the larval and adult stages of worms by targeting tubulin polymerization By inhibiting this process AL 27 disrupts the energy production within the worm leading to a significant decrease in its mobility This decrease in mobility ultimately results in the demise of the helminth The mechanism of action of AL 27 is based on its ability to interfere with tubulin a protein responsible for forming the worms structural cytoskeleton Tubulin plays a crucial role in maintaining the integrity of the worms cells and its polymerization is necessary for the proper function of the worms movements However AL 27 disrupts this process by binding to tubulin preventing its proper assembly into microtubules As a consequence the worm experiences a severe depletion of energy due to the disruption of its cytoskeletal structure This energy depletion renders the worm unable to perform essential functions required for its survival such as feeding and reproduction Additionally the decreased mobility caused by AL 27s action impairs the worms ability to evade host immune responses and find suitable environments for survival Ultimately thanks to its unique mechanism of action AL 27 effectively combats helminth infestations by targeting both larval and adult forms of the worm This potent compound disrupts tubulin polymerization resulting in energy depletion and diminished mobility leading to the worms demise
Medicines
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