Can you get high by using Piyox?

Can I use Piyox for a migraine?

Piyox is not approved for the treatment of migraine. Research studies have shown that Piyox is effective in significantly decreasing the pain associated with migraine without aura.

Is Piyox a muscle relaxant?

No. Piyox is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

What is the difference between Piyox and tramadol?

Piyox is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Are there any alternatives of Piyox?

Yes. There are alternatives to Piyox. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Can Piyox be used in the treatment of allergy?

No. Piyox is not a drug to treat allergy. It is a pain killer.

What is the difference between Piyox and naproxen?

Both Piyox and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Piyox.

How long does Piyox work?

Piyox is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can Piyox be used with calcium channel blocker?

Yes. Piyox can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

What is the difference between Piyox and diclofenac?

Both Piyox and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Piyox.

Are Piyox and aspirin same?

No. Piyox and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Is Piyox a blood thinner?

No. Piyox is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can you donate blood when on the medication with Piyox?

Yes. You can donate blood when on Piyox. Do inform your doctor before donating blood.

Can Piyox be used with methocarbamol?

Yes. Methocarbamol can be used with Piyox as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Piyox a NSAID?

Yes. Piyox is a non-steroidal anti-inflammatory drug (NSAID).

Is Piyox a narcotic?

No. Piyox is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Piyox be used along with dexamethasone?

No. Piyox should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Piyox?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Piyox be used in hypertension?

No. Piyox is not a medication to control hypertension. It is important to note that Piyox decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Piyox.

Why is beta cyclodextrin added to Piyox?

Yes. Piyox can be combined with beta-cyclodextrin. Research has shown that combining Piyox with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can Piyox be used with Tizanidine?

Yes, Piyox can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can Piyox be used with lithium?

No. Piyox should not be used with lithium. Piyox leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Can Piyox be used along with paracetamol?

Yes. Paracetamol can be used with Piyox as no serious side effects are known. Inform your doctor before starting any of the medication.

What are the serious side effects of Piyox?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can I use Piyox if I have peptic ulcer disease?

No. Piyox is contraindicated in cases of active peptic ulcer disease. Piyox is known to cause gastric ulceration and bleeding.

Can Piyox be used with warfarin?

No. Piyox should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Can Piyox lead to difficulty in conception?

Yes. Piyox can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can I use Piyox if I have a deranged renal function?

No. Piyox should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

Can I use Piyox if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can Piyox be used to treat menstrual cramp?

Piyox is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Is Piyox a sulfa drug?

Piyox is a sulphur containing compound. Piyox can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

What are the contraindications for Piyox?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.