Can I use Pexi if I have peptic ulcer disease?

What are the serious side effects of Pexi?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Is Pexi effective in back pain management?

Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pexi as the cause of back pain can be different for different person.

Can Pexi be used with calcium channel blocker?

Yes. Pexi can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Is Pexi a sulfa drug?

Pexi is a sulphur containing compound. Pexi can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

Is Pexi a NSAID?

Yes. Pexi is a non-steroidal anti-inflammatory drug (NSAID).

Can Pexi lead to difficulty in conception?

Yes. Pexi can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Can Pexi be used along with paracetamol?

Yes. Paracetamol can be used with Pexi as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Pexi a muscle relaxant?

No. Pexi is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

What increases the chances of getting a gastric ulcer when I am already taking Pexi?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Can Pexi be used along with Losartan?

No. Pexi should not be combined with Losartan. It is important to note that Pexi decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pexi.

Can I use Pexi if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can I use Pexi if I have a deranged renal function?

No. Pexi should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

Is Pexi affective in gout management?

Yes. Pexi can be given for the treatment of acute gout. Research studies have shown Pexi to be highly effective in the treatment of acute gout.

Can I use Pexi if I am a diabetic?

Pexi in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pexi so taking piroxicam can lead to increased risk of renal failure by many folds.

Are there any alternatives of Pexi?

Yes. There are alternatives to Pexi. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Can Pexi be used in the treatment of allergy?

No. Pexi is not a drug to treat allergy. It is a pain killer.

What are the contraindications for Pexi?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Why is beta cyclodextrin added to Pexi?

Yes. Pexi can be combined with beta-cyclodextrin. Research has shown that combining Pexi with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can you get high by using Pexi?

No. Pexi is not known to cause high. It is a non-narcotic painkiller.

Can I use Pexi if I am pregnant?

No. Pexi should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can Pexi be used with Tizanidine?

Yes, Pexi can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

What is the difference between Pexi and naproxen?

Both Pexi and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Pexi.

What is the difference between Pexi and nimesulide?

Both Pexi and nimesulide are pain killers. However, Pexi is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.

What is the difference between Pexi and meloxicam?

Both Pexi and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Pexi.

Can Pexi be used to treat menstrual cramp?

Pexi is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

What is the difference between Pexi and diclofenac?

Both Pexi and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Pexi.

How long does Pexi work?

Pexi is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can Pexi be used with methocarbamol?

Yes. Methocarbamol can be used with Pexi as no serious side effects are known. Inform your doctor before starting any of the medication.

What is the difference between Pexi and tramadol?

Pexi is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Can Pexi be used along with dexamethasone?

No. Pexi should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Is Pexi a blood thinner?

No. Pexi is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can I use Pexi for a migraine?

Pexi is not approved for the treatment of migraine. Research studies have shown that Pexi is effective in significantly decreasing the pain associated with migraine without aura.

What is the difference between Pexi and ketoprofen?

Both Pexi and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pexi. Ketoprofen gel also showed excellent tolerability.