Can I use Parinex if I have a deranged renal function?

What are the serious side effects of Parinex?

GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

Can Parinex be used with methocarbamol?

Yes. Methocarbamol can be used with Parinex as no serious side effects are known. Inform your doctor before starting any of the medication.

Is Parinex a narcotic?

No. Parinex is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Can Parinex be used along with Losartan?

No. Parinex should not be combined with Losartan. It is important to note that Parinex decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Parinex.

Is Parinex a NSAID?

Yes. Parinex is a non-steroidal anti-inflammatory drug (NSAID).

Can Parinex be used with Lisinopril?

No. Parinex should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Parinex.

Can Parinex be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Parinex or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Parinex.

Are Parinex and aspirin same?

No. Parinex and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

How long does Parinex work?

Parinex is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

What is the difference between Parinex and tramadol?

Parinex is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Is Parinex a muscle relaxant?

No. Parinex is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.

Can Parinex be used with lithium?

No. Parinex should not be used with lithium. Parinex leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Can Parinex be used with warfarin?

No. Parinex should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

Is Parinex a sulfa drug?

Parinex is a sulphur containing compound. Parinex can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

What increases the chances of getting a gastric ulcer when I am already taking Parinex?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Can I use Parinex if I am pregnant?

No. Parinex should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Can I use Parinex if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Can Parinex lead to skin reactions?

Yes. Parinex is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.

What is the difference between Parinex and meloxicam?

Both Parinex and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Parinex.

Can Parinex be used in the treatment of allergy?

No. Parinex is not a drug to treat allergy. It is a pain killer.

Can you donate blood when on the medication with Parinex?

Yes. You can donate blood when on Parinex. Do inform your doctor before donating blood.

Can Parinex be used with Tizanidine?

Yes, Parinex can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Why is beta cyclodextrin added to Parinex?

Yes. Parinex can be combined with beta-cyclodextrin. Research has shown that combining Parinex with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can Parinex be used along with paracetamol?

Yes. Paracetamol can be used with Parinex as no serious side effects are known. Inform your doctor before starting any of the medication.

Can Parinex be used with calcium channel blocker?

Yes. Parinex can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Are there any alternatives of Parinex?

Yes. There are alternatives to Parinex. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Parinex?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Parinex be used along with dexamethasone?

No. Parinex should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Is Parinex a blood thinner?

No. Parinex is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can I use Parinex for a migraine?

Parinex is not approved for the treatment of migraine. Research studies have shown that Parinex is effective in significantly decreasing the pain associated with migraine without aura.

Can I use Parinex if I am a diabetic?

Parinex in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Parinex so taking piroxicam can lead to increased risk of renal failure by many folds.