Can Doloxicam be used in hypertension?

Can Doloxicam be used along with Losartan?

No. Doloxicam should not be combined with Losartan. It is important to note that Doloxicam decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloxicam.

Can Doloxicam be used with warfarin?

No. Doloxicam should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.

What increases the chances of getting a gastric ulcer when I am already taking Doloxicam?

The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.

Can I use Doloxicam if I have peptic ulcer disease?

No. Doloxicam is contraindicated in cases of active peptic ulcer disease. Doloxicam is known to cause gastric ulceration and bleeding.

How long does Doloxicam work?

Doloxicam is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.

Can you get high by using Doloxicam?

No. Doloxicam is not known to cause high. It is a non-narcotic painkiller.

Can Doloxicam be used in the treatment of chikungunya?

Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Doloxicam or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Doloxicam.

Can Doloxicam be used along with dexamethasone?

No. Doloxicam should not be used with dexamethasone. They both increase each others toxicity. There is an increased risk of GI ulceration.

Can Doloxicam be used with Lisinopril?

No. Doloxicam should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Doloxicam.

Can Doloxicam be used with Tizanidine?

Yes, Doloxicam can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.

Can Doloxicam be used with calcium channel blocker?

Yes. Doloxicam can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)

Is Doloxicam a NSAID?

Yes. Doloxicam is a non-steroidal anti-inflammatory drug (NSAID).

What is the difference between Doloxicam and ketoprofen?

Both Doloxicam and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Doloxicam. Ketoprofen gel also showed excellent tolerability.

Is Doloxicam a blood thinner?

No. Doloxicam is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.

Can Doloxicam be used to treat menstrual cramp?

Doloxicam is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.

Is Doloxicam a narcotic?

No. Doloxicam is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.

Are Doloxicam and aspirin same?

No. Doloxicam and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.

Can you donate blood when on the medication with Doloxicam?

Yes. You can donate blood when on Doloxicam. Do inform your doctor before donating blood.

Can I use Doloxicam if I have asthma?

Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Is Doloxicam affective in gout management?

Yes. Doloxicam can be given for the treatment of acute gout. Research studies have shown Doloxicam to be highly effective in the treatment of acute gout.

Are there any alternatives of Doloxicam?

Yes. There are alternatives to Doloxicam. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.

Can I use Doloxicam if I have a deranged renal function?

No. Doloxicam should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.

What are the contraindications for Doloxicam?

Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.

Can Doloxicam be used with lithium?

No. Doloxicam should not be used with lithium. Doloxicam leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.

Can Doloxicam be used in the treatment of allergy?

No. Doloxicam is not a drug to treat allergy. It is a pain killer.

Why is beta cyclodextrin added to Doloxicam?

Yes. Doloxicam can be combined with beta-cyclodextrin. Research has shown that combining Doloxicam with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.

Can I use Doloxicam if I am pregnant?

No. Doloxicam should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.

Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Doloxicam?

Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.

Can Doloxicam lead to difficulty in conception?

Yes. Doloxicam can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

What is the difference between Doloxicam and tramadol?

Doloxicam is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.

Can I use Doloxicam for a migraine?

Doloxicam is not approved for the treatment of migraine. Research studies have shown that Doloxicam is effective in significantly decreasing the pain associated with migraine without aura.

Is Doloxicam a sulfa drug?

Doloxicam is a sulphur containing compound. Doloxicam can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.

What is the difference between Doloxicam and meloxicam?

Both Doloxicam and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Doloxicam.