ranphenicol CHLORAMPHENICOL

Introduction to ranphenicol

Ranphenicol is an antibiotic used to treat severe infections, especially when other antibiotics are not effective. It is particularly useful in treating conditions like typhoid fever and infections caused by the bacterium Haemophilus influenzae.

Composition of ranphenicol

Ranphenicol contains the active ingredient Chloramphenicol, which works by interfering with bacterial protein synthesis, thereby inhibiting the growth and reproduction of bacteria.

Uses of ranphenicol

• Treatment of severe infections such as typhoid fever.
• Effective against infections caused by Haemophilus influenzae.
• Used when other antibiotics are ineffective.

Side effects of ranphenicol

Common side effects:

• Nausea
• Vomiting
• Diarrhea

Serious side effects:

• Reversible bone marrow depression
• Irreversible aplastic anemia

Precautions of ranphenicol

Ranphenicol is contraindicated in individuals with hypersensitivity to the drug, during pregnancy and breastfeeding, and in patients with porphyria or those taking drugs that suppress bone marrow function. It should not be used for minor infections or during active immunization. Careful monitoring is required, especially in patients with hepatic or renal impairment.

How to Take ranphenicol

• Typically administered orally.
• For adults and the elderly, the usual daily dose is 50 mg per kg of body weight, divided into four doses.
• For severe infections, the dose may be doubled initially but should be reduced as soon as possible.

Conclusion of ranphenicol

Ranphenicol is a powerful antibiotic used to treat severe infections when other treatments fail. While effective, it is important to be aware of its potential side effects and contraindications. Always follow the prescribed dosage and consult with a healthcare professional for any concerns.