prib (PRIMAQUINE)
What is Prib?
Prib is an antimalarial medication used to treat malaria caused by the Plasmodium vivax and Plasmodium ovale parasites. It is also used to prevent malaria relapse by targeting the liver stages of the parasite. It works by disrupting the parasite's ability to multiply in the liver, reducing the chances of malaria reoccurring.
What is the usual dose of Prib?
For malaria prevention, the typical dose is 30 mg of Prib once daily for 14 days after travel to endemic areas. For relapse prevention, the dose may vary from 15 to 30 mg daily, depending on the severity of the condition. Always follow the doctor’s prescribed dosage for specific needs.
How do I take Prib?
Prib should be taken with food to reduce the risk of stomach upset. Swallow the tablets whole without crushing or chewing. The exact duration of treatment will depend on your doctor's recommendation, but it's usually a short-term regimen. Stick to the prescribed schedule, even if you feel better, to ensure effective treatment.
For how long do I take Prib?
For relapse prevention and malaria treatment, the usual course of Prib is between 7 to 14 days. The treatment duration depends on the nature of the malaria infection, and it’s essential to complete the full course as prescribed to prevent relapse and ensure complete parasite elimination.
What disease or symptom is Prib used for?
Prib is used to treat malaria, specifically infections caused by Plasmodium vivax and Plasmodium ovale. It is also effective in preventing relapse of malaria caused by these strains. Additionally, Prib can be used in combination therapy for certain types of P. falciparum malaria, though it is not the first-line treatment for this strain.
How long does it take for Prib to start working?
Prib begins to work soon after ingestion, and initial improvement in symptoms can be seen within a few days. However, it may take several weeks to fully eliminate the parasite and prevent a relapse. Completion of the entire course is necessary for optimal effectiveness, especially in preventing malaria relapse.
Is Prib effective?
Prib is highly effective for relapse prevention in P. vivax and P. ovale malaria. It works by targeting the liver stages of the parasite, which are often responsible for relapses. Studies show that when used as part of a comprehensive malaria treatment regimen, it significantly reduces the chances of malaria recurrence.
How do I know if Prib is working?
You’ll know Prib is working if you experience reduced fever, fatigue, and improvement in other malaria symptoms. Follow-up testing may be done to check for any remaining parasites in your blood. If no relapse occurs, it indicates the medicine was successful in eliminating the parasites and preventing re-infection.
How does Prib work?
Prib works by inhibiting the liver stage of malaria parasites, preventing them from multiplying and causing relapses. It kills the dormant forms of the parasite (hypnozoites) and ensures that the parasite does not re-enter the bloodstream, thus preventing further malaria attacks and reducing relapse risk.
Who should avoid taking Prib?
Individuals with G6PD deficiency, pregnant women (especially during the first trimester), or those with severe liver disease should avoid taking Prib. It can cause hemolytic anemia in those with G6PD deficiency. Always consult a doctor before taking Prib, especially if you have any health conditions or are pregnant or breastfeeding.
Can I take Prib with other prescription drugs?
Prib may interact with medications like chloroquine, hydroxychloroquine, or quinine. These combinations may either increase the effectiveness or cause harmful side effects. Inform your doctor about any prescription drugs you’re taking, as they may need to adjust your treatment to avoid harmful interactions.
Can Prib be taken safely while pregnant?
Prib is generally not recommended during pregnancy, especially in the first trimester, due to potential harm to the fetus. If malaria treatment is required during pregnancy, safer alternatives like chloroquine are typically used. Always consult your healthcare provider to assess risks and determine the safest treatment option.
Can Prib be taken safely while breastfeeding?
Prib can pass into breast milk, and although it is generally not recommended during breastfeeding, it may be used if the benefits outweigh the risks. Your doctor may suggest stopping breastfeeding or taking precautions to ensure the infant’s safety during treatment with Prib.
Is Prib safe for the elderly?
Prib can be used by the elderly but should be prescribed cautiously due to potential age-related liver or kidney issues. It is important to adjust the dose and monitor any adverse effects. Elderly patients should be closely monitored for hemolytic anemia and other related side effects during treatment.
How should I store Prib?
Store Prib at room temperature (between 20°C to 25°C), away from heat, moisture, and direct sunlight. Keep the medicine in its original packaging, tightly closed, and out of the reach of children. Do not store in the bathroom or near the kitchen sink, and properly dispose of expired medication.
Does Prib make people tired or drowsy?
Tiredness or drowsiness is not a common side effect of Prib, but some people may experience fatigue or dizziness. If you feel excessively tired or lightheaded, avoid activities like driving. Speak with your doctor if you notice these side effects, as they may adjust your treatment to better suit your needs.
Does Prib cause stomach upset?
Prib can cause nausea, vomiting, or abdominal discomfort. To minimize stomach upset, it’s best to take the medication with food. If these effects are bothersome or persist, speak to your doctor, who may recommend supportive treatments or advise on adjusting your medication.
Does Prib affect sleep?
Prib is not typically associated with sleep disturbances, but side effects such as fatigue or dizziness might indirectly affect sleep. If you experience sleep problems while on this medication, it’s advisable to speak with your healthcare provider to determine whether these symptoms are linked to the drug and how best to manage them.
Does Prib make it hard to think or concentrate?
Prib does not commonly cause cognitive issues like difficulty concentrating or thinking. However, dizziness and fatigue—which can occur with the medication—might make focusing or concentrating harder for some individuals. If this happens, avoid tasks requiring full attention, such as driving, and consult your doctor for further advice.
Does Prib affect mood?
Changes in mood are not typically associated with Prib, but some people may experience irritability, anxiety, or fatigue as side effects. If you notice mood changes that concern you, it’s important to consult your doctor. They can assess whether these symptoms are related to the medication and help manage them.
Does Prib interfere with sexual function?
Prib is not generally known to interfere with sexual function. However, if you experience side effects like fatigue or nausea, it could affect your overall well-being and potentially impact your libido. If sexual function issues arise, it’s a good idea to discuss them with your doctor to determine if an alternative treatment is necessary.
Does Prib affect appetite?
Prib can cause nausea, vomiting, or abdominal discomfort, which may result in a reduced appetite. To minimize this, it's recommended to take the medication with food. If appetite loss persists, or if weight changes occur, talk to your doctor who can guide you on managing these side effects or adjust your treatment plan.
Does Prib cause weight gain?
Weight gain is not a known side effect of Prib. However, any medication can affect people differently, and if you experience fluid retention or changes in weight, it’s important to monitor these changes and report them to your healthcare provider. They will evaluate whether these effects are related to the medication.
Does Prib cause headaches?
Headaches are a possible side effect of Prib, though not very common. If you experience headaches, try to stay hydrated, and if necessary, you can take an over-the-counter pain reliever after consulting your doctor. If headaches become frequent or severe, speak with your doctor, as they may adjust your treatment plan.
Does Prib limit driving?
Prib generally does not impair your ability to drive, but side effects like dizziness or fatigue can affect your alertness and concentration. If you feel lightheaded or overly tired, it’s best to avoid driving or operating heavy machinery. Consult your healthcare provider if these effects are concerning or persistent.
Is it safe to drink alcohol while taking Prib?
It is advisable to limit alcohol consumption while taking Prib. Alcohol can worsen certain side effects like dizziness and stomach upset, and may also affect your liver. If you choose to drink alcohol, speak with your doctor to understand the potential risks and determine whether it's safe during treatment.
Is it safe to drink coffee or tea while taking Prib?
Drinking moderate amounts of coffee or tea is generally safe while taking Prib. However, excessive caffeine consumption could exacerbate side effects like nervousness or insomnia. If you experience these symptoms, try reducing your caffeine intake. Always consult with your doctor if you have concerns regarding interactions between caffeine and the medication.
Is it safe to exercise while taking Prib?
Exercise is generally safe while taking Prib, but if you experience side effects like fatigue, dizziness, or nausea, you should consider adjusting the intensity or type of exercise. Speak with your doctor to ensure that your physical activity is safe and appropriate while undergoing treatment with Prib.
What are Prib possible harms and risks?
Common side effects of Prib include nausea, vomiting, abdominal pain, and headaches. Serious side effects, though rare, may include hemolytic anemia, especially in individuals with G6PD deficiency. Regular blood tests may be necessary to monitor for these risks, and you should inform your doctor about any existing conditions.
Available in 3 variations
Prib 2.5mg Tablet
Prib 2.5mg Tablet
Primaquine (2.5mg)
strip of 10 tablets
Prib 7.5mg Tablet
Prib 7.5mg Tablet
Primaquine (7.5mg)
strip of 10 tablets
Prib DS 15mg Tablet
Prib DS 15mg Tablet
Primaquine (15mg)
strip of 10 tablets
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