lofebril (FLUVOXAMINE)

What is Lofebril?

Lofebril is primarily used to treat obsessive-compulsive disorder (OCD) and social anxiety disorder. It works by increasing the levels of serotonin, a neurotransmitter, in the brain, which helps improve mood and reduce anxiety. It belongs to the class of selective serotonin reuptake inhibitors (SSRIs) and works by inhibiting the reuptake of serotonin, making more available for brain function. This helps reduce the symptoms of anxiety and obsessive thoughts.

How do I take Lofebril?

Lofebril can be taken with or without food, but should be taken at the same time each day to maintain a steady level of the medication in the body.

The tablets should be swallowed whole, without chewing or crushing.

Patients should avoid drinking alcohol while taking Lofebril, as it can increase the risk of side effects.

For how long do I take Lofebril?

Lofebril, in tablet form, has been shown to help adults with OCD long-term. While the long-term effects of the capsule form aren't as well-studied, doctors may still prescribe it if it's working well for the patient because OCD is a long-lasting condition. Studies also show it works for adults and kids in tablet form.

What is Lofebril used for?

Lofebril is used to treat OCD, SAD, GAD, panic disorder, PTSD, and major depressive disorder.

How long does it take for Lofebril to start working?

Lofebril can take 4-6 weeks to start working and patients may experience side effects during the first few weeks of treatment.

Is Lofebril effective?

Lofebril has been shown to effectively treat OCD, SAD, GAD, panic disorder, and MDD through increasing serotonin levels in the brain.

How does one know if Lofebril is working?

Patients should keep track of their symptoms and report any changes to their healthcare provider. This can help the provider to determine if the medication is working effectively.

Regular follow-up appointments with a healthcare provider can help to monitor the patient's response to Lofebril and make any necessary adjustments to the dosage.

How does Lofebril work?

Lofebril works by increasing serotonin levels in the brain, which can help to improve mood, reduce anxiety, and improve overall well-being.

Who should avoid taking Lofebril?

Allergic reactions: Lofebril can cause serious allergic reactions in some patients, including rash, hives, and difficulty breathing.

Suicidal thoughts: In some patients, Lofebril can cause an increase in suicidal thoughts, especially during the first few weeks of treatment.

Serotonin syndrome: Lofebril can interact with other medications to cause serotonin syndrome, a potentially life-threatening condition that can cause agitation, hallucinations, and coma.

Can I take Lofebril with vitamins or supplements?

St. John's Wort: This herbal supplement can increase the risk of side effects when taken with Lofebril, such as dizziness and drowsiness.

Calcium supplements: Calcium supplements can reduce the absorption of Lofebril, making it less effective.

Grapefruit juice: Grapefruit juice can increase the levels of Lofebril in the body, which can increase the risk of side effects.

Can I take Lofebril with other prescription drugs?

Monoamine oxidase inhibitors (MAOIs): MAOIs can cause a potentially life-threatening interaction with Lofebril, which can cause serotonin syndrome.

Tricyclic antidepressants: Taking Lofebril with tricyclic antidepressants can increase the risk of serotonin syndrome.

Warfarin: Lofebril can increase the levels of warfarin in the body, which can increase the risk of bleeding.

Can Lofebril be taken safely while pregnant?

Lofebril is classified as a Pregnancy Category C drug and it is not known whether it is safe for use during pregnancy. Pregnant women should consult with their healthcare provider before taking the medication.

Can Lofebril be taken safely while breastfeeding?

Lofebril can be excreted in breast milk and can cause adverse effects in nursing infants. Therefore, breastfeeding mothers should avoid taking Lofebril unless the potential benefits outweigh the potential risks.

Is Lofebril safe for the elderly?

Older adults need a smaller starting dose of the medicine Lofebril and should increase the dose slowly. This is because their bodies remove the medicine more slowly than younger people's, leading to a higher risk of low sodium levels in the blood (hyponatremia). However, studies before the medicine was sold didn't show any major overall safety differences between older and younger people taking it.

How should I store Lofebril?

Lofebril should be stored at room temperature, between 68°F and 77°F (20°C and 25°C), away from heat, moisture, and light.

Does Lofebril make people tired or drowsy?

Yes, Lofebril commonly causes drowsiness or tiredness, with somnolence reported in 26%-27% of patients. If you experience this side effect, avoid driving or activities requiring alertness and consult your doctor for guidance​

Does Lofebril cause stomach upset?

Common gastrointestinal side effects include nausea (34%-39%), diarrhea (14%-18%), and anorexia (13%-14%). To ease symptoms, try taking the medicine with food and inform your doctor if the issue persists​

Does Lofebril affect sleep?

Insomnia is reported in 32%-35% of patients. If sleep issues arise, consider adjusting the timing of your dose or ask your doctor for advice on managing this side effect​

Does Lofebril make it hard to think or concentrate?

Cognitive effects like dizziness (12%-15%) and abnormal thinking (3%) can occur. If concentration becomes difficult, limit activities requiring focus and speak with your doctor about possible solutions​

Does Lofebril affect mood?

Mood changes, such as anxiety (6%-8%) and agitation (2%-3%), have been reported. Contact your doctor if you notice significant mood shifts or worsening symptoms​

Does Lofebril interfere with sexual function?

Lofebril commonly causes sexual side effects like decreased libido (6%-8%) and abnormal ejaculation (11%). Discuss these concerns with your doctor to explore management options​

Does Lofebril affect appetite?

Reduced appetite (13%-14%) and weight loss (2%) are common side effects. If appetite changes are severe or affect your health, consult your doctor for advice

Does Lofebril cause weight gain?

Weight changes, including weight gain, have been observed infrequently. If you experience significant weight changes, speak with your doctor

Does Lofebril cause headaches?

Headaches occur in 32%-35% of patients. Stay hydrated, use over-the-counter pain relievers if needed, and talk to your doctor if the headaches persist

Does Lofebril limit driving?

Lofebril may impair your ability to drive due to drowsiness or dizziness. Avoid driving until you know how the medicine affects you and consult your doctor if needed

Is it safe to drink alcohol while taking Lofebril?

Drinking alcohol in moderation does not directly affect the safety or effectiveness of Dutasteride. However, both alcohol and Dutasteride can lower blood pressure, so combining the two could lead to increased dizziness or lightheadedness. It's important to stay hydrated and monitor any changes in how you feel. Always consult your doctor for personalized advice​

Is it safe to drink coffee or tea while taking Lofebril?

Caffeinated beverages such as coffee or tea do not interfere with the effectiveness of Dutasteride. However, caffeine can cause mild dehydration, which might affect your overall health. Drinking these beverages in moderation should not pose a problem, but staying hydrated is essential for managing your health

Is it safe to exercise while taking Lofebril?

Exercise is generally safe while taking Dutasteride. However, Dutasteride can sometimes cause dizziness or fatigue, so it's important to listen to your body and avoid intense physical activity if you feel unwell. Start with moderate exercises and gradually increase intensity while being mindful of any side effects you experience. Always consult your healthcare provider if you have any concerns​

What are Lofebril possible harms and risks?

Lofebril may cause common side effects such as nausea, diarrhea, and dizziness, and rare adverse effects such as abnormal bleeding or seizures.