lendomy (LENALIDOMIDE)

What is Lendomy?

Lendomy is a cancer medicine used to treat multiple myeloma, myelodysplastic syndromes (MDS), and mantle cell lymphoma (MCL). It works by modifying the immune system and slowing the growth of abnormal cells. It also helps prevent tumor blood vessel formation, making it harder for cancer cells to spread.

What is the usual dose of Lendomy?

The dose depends on the condition:

• Multiple Myeloma: 25 mg once daily for 21 days in a 28-day cycle.
• MDS: 10 mg once daily.
• MCL: 25 mg once daily for 21 days in a 28-day cycle.
  Dosage adjustments may be needed based on kidney function and side effects.

How do I take Lendomy?

Take Lendomy by mouth, with or without food, at the same time daily. Swallow the capsule whole with water; do not break or chew it. Avoid handling broken or crushed capsules. Women of childbearing age must use effective contraception due to serious birth defects risk.

For how long do I take Lendomy?

The treatment duration varies based on the condition and response. For multiple myeloma, it is taken long-term with periodic breaks. For MDS or MCL, treatment continues as long as it is effective and tolerated. The doctor will monitor and adjust treatment based on progress.

What disease or symptom is Lendomy used for?

Lendomy is primarily used to treat multiple myeloma (a type of blood cancer), myelodysplastic syndromes (MDS), and mantle cell lymphoma (MCL). It helps slow the growth of cancer cells, boosts the immune system, and prevents tumors from forming new blood vessels.

How long does it take for Lendomy to start working?

Lendomy does not provide instant relief . It may take weeks to months before significant improvements are seen. Blood tests and regular check-ups help track progress. Patients should continue taking it as prescribed, even if results are not immediately noticeable.

Is Lendomy effective?

Yes, clinical studies show Lendomy improves survival rates and slows cancer progression, especially in multiple myeloma and MDS. It works best when combined with other treatments like dexamethasone or chemotherapy. However, effectiveness varies based on individual response.

How do I know if Lendomy is working?

Doctors monitor blood tests, imaging scans, and symptom improvement to check effectiveness. In multiple myeloma, a decrease in M-protein levels indicates progress. In MDS, improved blood counts suggest a positive response. Symptoms like fatigue and pain may also improve over time.

How does Lendomy work?

Lendomy works in multiple ways: it modifies the immune system, prevents tumor blood vessel formation, and slows cancer cell growth. It enhances the body's ability to fight abnormal cells while reducing inflammation and stopping cancer cells from spreading.

Who should avoid taking Lendomy?

• Pregnant women (due to severe birth defects).
• People with severe kidney disease, unless adjusted by a doctor.
• Patients with a history of blood clots (high clotting risk).
• Those allergic to Lendomy or similar drugs like thalidomide.

Can I take Lendomy with other prescription drugs?

Lendomy interacts with blood thinners (warfarin, aspirin), steroids, and some antibiotics. Combining it with other drugs that affect the immune system or blood cells may increase side effects. Always inform your doctor about all medications you take.

Can Lendomy be taken safely while pregnant?

No! Lendomy causes severe birth defects or miscarriage. Women of childbearing age must take two forms of birth control and undergo pregnancy tests before and during treatment. It should be completely avoided during pregnancy.

Can Lendomy be taken safely while breastfeeding?

No, Lendomy should not be used while breastfeeding. It may pass into breast milk and harm the baby. If treatment is necessary, breastfeeding must be stopped. Consult a doctor for alternative feeding options.

Is Lendomy safe for the elderly?

Yes, but elderly patients have a higher risk of blood clots, low blood counts, and infections. Kidney function is often reduced with age, requiring dose adjustments. Close monitoring helps minimize risks.

How should I store Lendomy?

Store Lendomy at room temperature (20–25°C), away from heat, moisture, and direct sunlight. Keep it in its original container and out of reach of children. Do not handle broken capsules, as the powder can be harmful if inhaled or touched.

Does Lendomy make people tired or drowsy?

Yes, fatigue and drowsiness are common side effects, affecting about 1 in 3 people. If you feel excessively tired, avoid driving or operating heavy machinery. Taking the medicine at night may help. If fatigue worsens or affects daily activities, consult your doctor for possible dose adjustments or supportive care.

Does Lendomy cause stomach upset?

Yes, nausea, vomiting, diarrhea, and abdominal pain are frequent side effects. These symptoms occur in about 20–30% of patients. Taking Lendomy with food and staying hydrated can help. If severe diarrhea or vomiting occurs, contact your doctor, as dehydration can be dangerous and may require medical intervention.

Does Lendomy affect sleep?

Some people experience insomnia (trouble sleeping) while taking Lendomy. This can be due to the body's immune response or related side effects like anxiety or discomfort. Avoid caffeine before bedtime and maintain a healthy sleep routine. If insomnia persists, consult your doctor for solutions like dose timing adjustments or sleep aids.

Does Lendomy make it hard to think or concentrate?

Yes, difficulty concentrating, memory problems, and confusion have been reported. These effects, sometimes called “chemo brain,” can occur in about 10–15% of patients. If you experience these issues, avoid complex tasks like driving. Regular mental exercises, staying hydrated, and getting enough rest may help manage cognitive difficulties.

Does Lendomy affect mood?

Yes, depression, anxiety, and mood swings can occur, though not in everyone. The stress of dealing with cancer and medication side effects may contribute to emotional changes. If you experience severe sadness, anxiety, or suicidal thoughts, seek medical help immediately. Counseling or medication adjustments may help manage mood changes.

Does Lendomy interfere with sexual function?

Yes, Lendomy may reduce libido (sex drive) and cause erectile dysfunction in men. This is due to its effects on hormones, blood circulation, and energy levels. If sexual problems persist, discuss them with your doctor. They may suggest lifestyle changes, medication adjustments, or treatments to improve sexual health.

Does Lendomy affect appetite?

Yes, loss of appetite is common. Some patients feel less hungry or experience taste changes, leading to reduced food intake. Eating small, frequent meals, choosing nutrient-dense foods, and staying hydrated can help. If appetite loss leads to weight loss or weakness, consult your doctor for nutritional support.

Does Lendomy cause weight gain?

Weight changes vary—some people lose weight due to appetite loss, while others gain weight due to fluid retention or reduced physical activity. Monitoring your weight regularly and maintaining a balanced diet can help. If significant weight changes occur, discuss them with your doctor for proper management.

Does Lendomy cause headaches?

Yes, headaches can occur, often mild to moderate. Staying hydrated, avoiding stress, and getting enough rest can help. If headaches are severe or persistent, talk to your doctor. They may recommend pain relievers that do not interfere with Lendomy.

Does Lendomy limit driving?

Lendomy can cause dizziness, drowsiness, and difficulty concentrating, which may impair driving. If you experience these effects, avoid operating vehicles or heavy machinery. Test your reaction to the medicine before driving long distances. If side effects persist, consult your doctor for advice.

Is it safe to drink alcohol while taking Lendomy?

It’s not recommended to drink alcohol while on Lendomy. Alcohol can increase dizziness, drowsiness, and liver strain, making side effects worse. If you choose to drink occasionally, limit intake and monitor how you feel. Always check with your doctor before drinking alcohol while on this medication.

Is it safe to drink coffee or tea while taking Lendomy?

Caffeinated drinks like coffee and tea are generally safe, but they may worsen insomnia, anxiety, or stomach irritation caused by Lendomy. If you experience these side effects, try reducing caffeine intake. Staying hydrated with water or herbal teas may be a better option.

Is it safe to exercise while taking Lendomy?

Yes, but moderate exercise is recommended. Light activities like walking, yoga, or stretching can help improve energy levels, mood, and circulation. Avoid intense workouts if you feel fatigued or dizzy. Listen to your body, and consult your doctor before starting or adjusting your exercise routine.

What are Lendomy possible harms and risks?

Common side effects include fatigue, nausea, diarrhea, and skin rashes. Serious risks include blood clots, low blood cell counts, liver issues, and an increased risk of secondary cancers. Women must avoid pregnancy due to severe birth defects risk. Regular monitoring helps detect and manage risks early.