Ketofine 30mg Injection (KETOROLAC)
What is Ketofine injection?
Ketofine injection is a strong pain reliever used for a short time after surgery, usually only up to 5 days. It works similarly to other pain relievers like ibuprofen, but stronger. Though doctors aren't entirely sure how it works, it's thought to block something in your body that causes pain and swelling. It's best given as a shot or through an IV at first, then you might take it as a pill. Only a specific part of the drug actually helps with pain.
What is the usual dose of Ketofine injection?
This medicine (Ketofine injection tromethamine) is for adults only. Most adults take 20mg to start, then 10mg every 4 to 6 hours if needed, but no more than 40mg total in a day. Older adults, people with kidney problems, or those weighing less than 50 kg should start with 10mg and take 10mg every 4 to 6 hours as needed, again, not exceeding 40mg total daily. It's not for children.
How do I take Ketofine injection?
Ketofine injection should be taken orally, typically with food to minimize gastrointestinal irritation. Do not exceed the prescribed dose or shorten the interval between doses (minimum 4-6 hours).
For how long do I take Ketofine injection?
Ketofine injection is a strong pain reliever. For grown-ups, whether you take it as a pill or injection, you shouldn't use it for more than 5 days total. It's not safe for children.
What disease or symptom is Ketofine injection used for?
Ketofine injection tablets are strong pain relievers, similar to opioid painkillers, but only for short-term use (up to 5 days) in adults with moderate to severe pain. They're only meant to continue pain relief if you've already had shots or IV medication of the same drug. They're not for children or for mild or long-lasting pain.
How long does it take for Ketofine injection to start working?
Peak analgesic effect occurs within 2-3 hours after oral administration.
Is Ketofine injection effective?
Ketofine injection has been proven effective for short-term acute pain management in clinical studies, reducing the need for opioids in postoperative settings.
How do I know if Ketofine injection is working?
Reduction in pain levels after administration is the primary indicator of its effectiveness.
This medicine needs careful monitoring. Watch for signs of stomach bleeding (like blood in your stool). Your doctor will regularly check your blood to make sure it's working correctly. If you have liver or kidney problems, the doctor might stop the medicine if your liver tests get worse. Always take the smallest amount needed, and only for as long as necessary.
How does Ketofine injection work?
Ketofine injection inhibits prostaglandin synthesis by blocking cyclooxygenase (COX), which reduces inflammation and pain.
Ketofine injection is a strong pain reliever. Almost all of it sticks to proteins in your blood. It's made of two mirror-image parts, but both work the same. It doesn't affect how your liver processes other medicines. However, it can make some water pills less effective. You shouldn't take it with probenecid because that combination makes way too much Ketofine injection build up in your blood.
Who should avoid taking Ketofine injection?
This medicine is a strong pain reliever, but it's only for short-term use (5 days max) in adults. Don't take it if you're pregnant (after the 7th month), have a stomach ulcer, or have recently had stomach bleeding. It can raise your risk of heart attack, stroke, and serious stomach problems. Watch for signs of liver trouble (feeling sick, tired, yellow skin) or allergic reaction (rash, fever). If you have trouble breathing, gain weight suddenly, or swell up, get help right away.
Can I take Ketofine injection with other prescription drugs?
If you're taking water pills (like thiazide or loop diuretics) and pain relievers (NSAIDs, including Toradol), your water pills might not work as well. NSAIDs can also affect blood pressure, especially if you already have high blood pressure. It's very important to talk to your doctor before starting any new medicines, especially if you’re already on other medications for high blood pressure.
Can Ketofine injection be taken safely while pregnant?
NSAIDs like Ketofine injection can harm a baby during pregnancy, especially after 30 weeks. They may cause the baby's blood vessel (ductus arteriosus) to close too early. Even between 20 and 30 weeks, these medicines should be used very carefully and only for a short time because they've been linked to kidney problems for the baby. After 30 weeks, it's best to avoid them completely.
Can Ketofine injection be taken safely while breastfeeding?
A small amount of the pain medicine Ketofine injection can pass into breast milk. In a study, it wasn't even found in most mothers' milk. Even when it was present, the amount a baby would get was very, very small—much less than the mother's dose. However, it's still best to talk to your baby's doctor if you have any concerns.
Is Ketofine injection safe for the elderly?
Ketofine injection is a pain reliever, but older people (65 and up) need to be very careful with it. Their bodies get rid of it more slowly, making them more likely to have side effects like stomach problems. Doctors should give them lower doses and watch them closely to prevent serious issues. Older adults are at higher risk of bad stomach problems from this medicine.
How should I store Ketofine injection?
Keep the container tightly closed, away from light and dampness. It needs to be stored where kids can't get to it, at a room temperature between 68° and 77°F (a little warmer or cooler is okay).
Does Ketofine injection make people tired or drowsy?
Drowsiness is a common side effect. Avoid driving or operating machinery if affected.
Does Ketofine injection cause stomach upset?
Yes, nausea, dyspepsia, and abdominal pain are common. Taking it with food may help.
Does Ketofine injection affect sleep?
Insomnia is mentioned as a rare side effect. If it occurs, consult your healthcare provider.
Does Ketofine injection make it hard to think or concentrate?
Dizziness and confusion are potential side effects. Avoid activities requiring focus if affected.
Does Ketofine injection affect mood?
Anxiety, nervousness, and depression are infrequently reported.
Does Ketofine injection interfere with sexual function?
Sexual side effects are infrequently reported.
Does Ketofine injection affect appetite?
Anorexia has been reported as a side effect, though it is uncommon.
Does Ketofine injection cause weight gain?
If you notice you're gaining weight unexpectedly or your body is swelling, tell your doctor right away. These could be side effects of something.
Does Ketofine injection cause headaches?
Some pain relievers called NSAIDs can sometimes cause headaches. If you get a headache after taking one, stop taking it right away and see a doctor or other healthcare professional.
Does Ketofine injection limit driving?
Drowsiness and dizziness may impair driving. Avoid driving if these symptoms occur.
Is it safe to drink alcohol while taking Ketofine injection?
Alcohol increases the risk of GI bleeding and should be avoided during treatment.
Is it safe to drink coffee or tea while taking Ketofine injection?
No specific restrictions on caffeinated beverages are mentioned.
Is it safe to exercise while taking Ketofine injection?
Exercise is not contraindicated, but avoid strenuous activity if experiencing side effects like dizziness or drowsiness.
What are Ketofine injection possible harms and risks?
NSAIDs can upset your stomach, causing pain, gas, diarrhea, or constipation. They can also make you dizzy, nauseous, or vomit. Rarely, but seriously, they can harm your liver or kidneys, increase your risk of heart attack or stroke, cause anemia, or trigger severe skin or allergic reactions. Some people get slightly abnormal liver tests, but serious liver problems are uncommon.
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