glidapaflozin (DAPAGLIFLOZIN)
Introduction to glidapaflozin
Glidapaflozin is a medication primarily used to manage conditions like type 2 diabetes and heart failure. It is also prescribed for patients with chronic kidney disease. T... See More
What is Glidapaflozin?
Glidapaflozin is used to manage type 2 diabetes, reduce the risk of hospitalization for heart failure, and treat chronic kidney disease. It works by inhibiting the sodium-glucose co-transporter 2 (SGLT2) in the kidneys, which increases glucose excretion in urine, thereby lowering blood sugar levels. It also helps reduce cardiovascular risks and improve kidney function.
How do I take Glidapaflozin?
Glidapaflozin should be taken once daily, with or without food, at the same time each day. There are no specific food restrictions while taking this medication, but it is important to follow a healthy diet and exercise plan as recommended by your doctor. Always follow your doctor's instructions regarding the use of this medication.
For how long do I take Glidapaflozin?
Glidapaflozin is typically used as a long-term treatment for managing type 2 diabetes, heart failure, or chronic kidney disease. The duration of use depends on the individual's response to the medication and the specific condition being treated. It is important to continue taking Glidapaflozin as prescribed by your doctor, even if you feel well.
What is Glidapaflozin used for?
Glidapaflozin is indicated for the management of type 2 diabetes in adults and children aged 10 years and older, to improve glycemic control when used alongside diet and exercise. It is also used to reduce the risk of hospitalization for heart failure and cardiovascular death in adults with heart failure or chronic kidney disease. Additionally, it helps reduce the risk of worsening kidney disease.
How long does it take for Glidapaflozin to start working?
Glidapaflozin begins to work within a few hours of taking the first dose, as it starts to increase glucose excretion in the urine. However, it may take several weeks to see the full effects on blood sugar levels. Regular monitoring of blood sugar is important to assess the medication's effectiveness.
Is Glidapaflozin effective?
Glidapaflozin has been shown to effectively lower blood sugar levels in adults and children with type 2 diabetes when used alongside diet and exercise. It also reduces the risk of hospitalization for heart failure and cardiovascular death in adults with heart failure or chronic kidney disease. Clinical trials have demonstrated its efficacy in improving glycemic control and reducing cardiovascular and renal events.
How does one know if Glidapaflozin is working?
The benefit of Glidapaflozin is evaluated through regular monitoring of blood sugar levels and other laboratory tests, such as glycosylated hemoglobin (HbA1c) and kidney function tests. Patients are advised to regularly check their blood sugar levels at home and report any significant changes to their doctor. Regular follow-up appointments with healthcare providers are essential to assess the medication's effectiveness and adjust treatment as needed.
How does Glidapaflozin work?
Glidapaflozin works by inhibiting the sodium-glucose co-transporter 2 (SGLT2) in the kidneys. This action prevents the reabsorption of glucose back into the bloodstream, leading to increased glucose excretion in the urine. As a result, blood sugar levels are lowered, which helps manage type 2 diabetes and reduces cardiovascular and renal risks.
Who should avoid taking Glidapaflozin?
Glidapaflozin is contraindicated in patients with a history of serious hypersensitivity reactions to the drug. It is not recommended for use in patients with type 1 diabetes or diabetic ketoacidosis. Caution is advised in patients with renal impairment, as the drug's efficacy is reduced. Patients should be aware of the risk of dehydration, urinary tract infections, and ketoacidosis, and should monitor for symptoms.
Can I take Glidapaflozin with other prescription drugs?
Glidapaflozin may increase the risk of hypoglycemia when used with insulin or insulin secretagogues, such as sulfonylureas. A lower dose of insulin or insulin secretagogue may be required. It may also interact with diuretics, increasing the risk of dehydration and hypotension. Patients should inform their doctor of all medications they are taking to avoid potential interactions.
Can Glidapaflozin be taken safely while pregnant?
Glidapaflozin is not recommended during the second and third trimesters of pregnancy due to potential adverse effects on fetal kidney development, as observed in animal studies. There is limited data on its use in pregnant women, and the risks to the fetus are not fully known. Pregnant women should discuss alternative treatments with their healthcare provider.
Can Glidapaflozin be taken safely while breastfeeding?
It is not known if Glidapaflozin passes into human breast milk, but it is present in the milk of lactating rats. Due to the potential risk to the developing human kidney, breastfeeding is not recommended while taking Glidapaflozin. Women should discuss alternative treatments with their healthcare provider if they are breastfeeding or plan to breastfeed.
Is Glidapaflozin safe for the elderly?
Elderly patients may be at a greater risk for volume depletion and are more likely to be treated with diuretics. They are also more likely to have impaired renal function. Therefore, it is important to monitor renal function and volume status in elderly patients taking Glidapaflozin. No specific dosage adjustment is recommended based on age alone, but caution is advised.
How should I store Glidapaflozin?
Glidapaflozin should be stored at room temperature, between 20°C to 25°C (68°F to 77°F), and kept in its original container, tightly closed, and out of reach of children. It should be stored away from excess heat and moisture, and not in the bathroom. Unneeded medication should be disposed of properly, preferably through a take-back program.
Does Glidapaflozin make people tired or drowsy?
Glidapaflozin may cause fatigue or tiredness, although these are not among the most commonly reported side effects. If you experience significant fatigue or drowsiness, it is important to discuss these symptoms with your doctor. They may need to adjust your treatment plan or investigate other potential causes of these symptoms.
Does Glidapaflozin cause stomach upset?
Common gastrointestinal side effects of Glidapaflozin include nausea and constipation. If you experience severe or persistent gastrointestinal symptoms, it is important to contact your doctor. They may need to adjust your medication or provide additional treatment to manage these side effects.
Does Glidapaflozin affect appetite?
Glidapaflozin may cause a decrease in appetite as a side effect, although this is not commonly reported. If you experience significant changes in appetite, it is important to discuss this with your doctor. They may need to adjust your treatment plan or investigate other potential causes of these symptoms.
Does Glidapaflozin cause weight gain?
Glidapaflozin is known to cause weight loss, which is a common effect due to its mechanism of action that leads to glucose excretion in urine. If you experience significant or unintended weight loss, it is important to discuss this with your doctor. They may need to adjust your treatment plan or investigate other potential causes of weight changes.
Does Glidapaflozin cause headaches?
Headaches are not commonly reported as a side effect of Glidapaflozin. However, if you experience persistent or severe headaches while taking this medication, it is important to consult your doctor. They may need to adjust your treatment or investigate other potential causes of the headaches.
Does Glidapaflozin limit driving?
Glidapaflozin may cause dizziness or lightheadedness, especially when getting up from a lying position. These symptoms can affect your ability to drive safely. If you experience these symptoms, it is important to avoid driving or operating heavy machinery until you feel better. Always consult your doctor if you have concerns about driving while taking this medication.
What are Glidapaflozin possible harms and risks?
Common side effects of Glidapaflozin include urinary tract infections, genital infections, and increased urination. Serious adverse effects can include ketoacidosis, dehydration, and acute kidney injury. The frequency of these side effects varies, with genital infections occurring in about 5% of patients. Patients should report any severe or persistent side effects to their doctor immediately.
Available in 2 variations
Glidapaflozin 10mg Tablet
Dapagliflozin (10mg)
strip of 15 tablets
Glidapaflozin 5mg Tablet 15s
Dapagliflozin (5mg)
strip of 15 tablets
.svg)
