desvelaf (DESVENLAFAXINE)
Introduction to Desvelaf
Desvelaf is a prescription medication primarily used to treat major depressive disorder (MDD) in adults. It belongs to a class of drugs known as serotonin-norepinephrine reupta... See More
What is Desvelaf?
Desvelaf is commonly used to treat depression, generalized anxiety disorder, and sometimes, diabetic neuropathy. It works by increasing the levels of serotonin and norepinephrine in the brain, which are neurotransmitters that help regulate mood and pain. This helps alleviate symptoms of depression and anxiety. It belongs to the class of medications called serotonin-norepinephrine reuptake inhibitors (SNRIs).
How do I take Desvelaf?
Desvelaf can be taken with or without food. It is important to swallow the tablets whole, without crushing, chewing, or breaking them, to avoid releasing too much of the drug at once. There are no specific food restrictions, but it’s recommended to avoid alcohol as it may increase side effects like dizziness or drowsiness. Always follow your healthcare provider's instructions for use.
For how long do I take Desvelaf?
The typical duration of use for Desvelaf depends on the condition being treated and individual patient needs: Acute Treatment : For major depressive disorder (MDD), acute treatment generally lasts several weeks to months. The initial treatment period often spans 8-12 weeks to assess the medication's effectiveness. Continuation and Maintenance : Continuation therapy for MDD is recommended for several months or longer to prevent relapse. Longer-term maintenance therapy may be necessary for individuals with recurrent depression or chronic symptoms. Periodic Reassessment : Patients should be periodically reassessed to determine the need for continued treatment. The decision to extend or discontinue therapy depends on clinical improvement, relapse history, and overall health.
What disease or symptom is Desvelaf used for?
Desvelaf is primarily used to treat major depressive disorder (MDD) and generalized anxiety disorder (GAD). It is also prescribed to manage symptoms of neuropathic pain, particularly in diabetic peripheral neuropathy, and in some cases, for stress urinary incontinence.
How long does it take for Desvelaf to start working?
Desvelaf may take 1 to 2 weeks to show initial effects, but it can take up to 4 to 6 weeks for the full benefits, especially in treating depression and anxiety. It is important to continue taking the medication as prescribed and consult a doctor if symptoms do not improve.
Is Desvelaf effective?
Studies show that Desvelaf effectively treats major depressive disorder (MDD) and generalized anxiety disorder (GAD). Clinical trials have demonstrated significant improvements in mood, anxiety, and overall functioning in patients compared to placebo. Additionally, it has been shown to reduce physical symptoms of depression, such as pain, providing more comprehensive symptom relief.
How does one know if Desvelaf is working?
The benefit of Desvelaf is evaluated through clinical assessments such as the Hamilton Depression Rating Scale (HDRS) and the Generalized Anxiety Disorder 7 (GAD-7) scale. Improvement in symptoms, including mood, anxiety, and quality of life, is monitored. Additionally, healthcare providers assess side effects and overall functioning during follow-up visits to gauge its effectiveness and safety.
How does Desvelaf work?
Desvelaf is a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by increasing the levels of serotonin and norepinephrine in the brain by inhibiting their reuptake into nerve cells. This helps improve mood, relieve anxiety, and manage pain, as both serotonin and norepinephrine play key roles in regulating these functions.
Who should avoid taking Desvelaf?
Desvelaf should be used with caution in individuals with a history of high blood pressure, heart problems, or liver/kidney issues. It is contraindicated in those with uncontrolled glaucoma or a history of serotonin syndrome. Caution is also needed for those with a history of depression, bipolar disorder, or suicidal thoughts, as it may increase risks.
Can I take Desvelaf with other prescription drugs?
Desvelaf may interact with other antidepressants, especially SSRIs, SNRIs, or MAO inhibitors, increasing the risk of serotonin syndrome. It can also interact with blood thinners like warfarin, increasing bleeding risks, and medications that affect liver enzymes (e.g., ketoconazole) may alter its effectiveness. Always consult a healthcare provider before combining medications.
Can Desvelaf be taken safely while pregnant?
Desvelaf is classified as a Category C drug for pregnancy, indicating that risk to the fetus cannot be ruled out. Animal studies have shown some adverse effects, but there are no well-controlled studies in pregnant women. It should only be used if the potential benefits outweigh the risks, and patients should consult their doctor before use during pregnancy.
Can Desvelaf be taken safely while breastfeeding?
Desvelaf is excreted in breast milk, but the effects on a nursing infant are not well-studied. It is recommended to use caution when prescribing this medication to breastfeeding mothers. If necessary, a healthcare provider may suggest monitoring the infant for potential side effects or considering alternative treatments while breastfeeding.
Is Desvelaf safe for the elderly?
**For older adults:** * **Kidney function:** The kidneys may not work as well, so the dosage may need to be adjusted. * **Blood pressure:** Desvelaf can lower blood pressure, especially when standing up. This is more common in older adults. * **Sodium levels:** Desvelaf can lower sodium levels in the blood, which can be more dangerous for older adults. * **Suicidal thoughts:** Antidepressants like Desvelaf may reduce the risk of suicidal thoughts in older adults.
How should I store Desvelaf?
Desvelaf should be stored at room temperature, away from moisture, heat, and direct sunlight. It should be kept in its original packaging to protect it from moisture. Ensure that the medication is stored out of reach of children and is not used after its expiration date.
Does Desvelaf make people tired or drowsy?
Fatigue was reported in up to 7% of patients, particularly at higher doses. If fatigue occurs and affects daily functioning, consult a doctor for potential dose adjustments.
Does Desvelaf cause stomach upset?
Gastrointestinal side effects include nausea (up to 22% at the recommended dose), constipation (up to 9%), and dry mouth (up to 11%). If these symptoms persist, consult your healthcare provider for management options.
Does Desvelaf affect sleep?
Insomnia occurred in up to 9% of patients at the recommended dose and increased with higher doses. If sleep problems persist, discuss with your doctor for potential solutions.
Does Desvelaf make it hard to think or concentrate?
Cognitive effects, including somnolence (4%) and dizziness (13%), were noted, particularly at higher doses. If concentration issues interfere with daily activities, avoid driving or operating machinery and inform your doctor.
Does Desvelaf affect mood?
While Desvelaf treats depression, it may cause anxiety (3%) or emotional changes. Patients should monitor mood closely and report significant changes, especially early in treatment.
Does Desvelaf interfere with sexual function?
Sexual dysfunction, including decreased libido (4%) and difficulty with orgasm (up to 5% in men), was reported. If these effects are bothersome, consult your healthcare provider for advice
Does Desvelaf affect appetite?
Desvelaf can cause decreased appetite in more than 10% of people who take it. This side effect is more common at higher doses of the medication. If you experience a change in your appetite while taking Desvelaf, talk to your doctor.
Does Desvelaf cause weight gain?
Desvelaf may cause weight loss, but the amount of weight loss varies. In studies, people taking Desvelaf lost between 0 and 1.1 kg. It's not known how often this side effect occurs. If you experience weight changes while taking Desvelaf, talk to your doctor.
Does Desvelaf cause headaches?
Desvelaf usually doesn't cause headaches as a common side effect. However, if high doses of the medication are stopped abruptly, it can lead to withdrawal symptoms, including headaches. If you experience a headache after discontinuing Desvelaf, consult your healthcare provider.
Does Desvelaf limit driving?
Desvelaf can make you feel drowsy or lightheaded. You should not drive or use heavy machinery until you know how the medicine affects you. If you have trouble driving, stop driving and call your doctor right away.
What are Desvelaf possible harms and risks?
Common side effects of Desvelaf include nausea, dry mouth, dizziness, insomnia, constipation, and sweating. Serious adverse effects may include increased blood pressure, serotonin syndrome (symptoms like agitation, hallucinations), suicidal thoughts, and withdrawal symptoms upon abrupt discontinuation. Monitoring blood pressure and mental health is recommended during treatment.
Available in 2 variations
Desvelaf 50mg Tablet ER
Desvelaf 50mg Tablet ER
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strip of 10 tablet er
Desvelaf 100mg Tablet ER
Desvelaf 100mg Tablet ER
Desvenlafaxine (100mg)
strip of 10 tablet er
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