Bigora 100mg Tablet (SILDENAFIL)

What is Bigora tablet?

Bigora tablet is commonly used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which helps relax blood vessels and improve blood flow to specific areas, such as the penis or lungs. This improved blood flow allows for better erectile function or reduced pulmonary blood pressure, depending on the condition being treated.

What is the usual dose of Bigora tablet?

For Erectile Dysfunction (ED):

• The recommended starting dose is 50 mg, taken 30 minutes to 1 hour before sexual activity, as needed.
• Depending on effectiveness and tolerance, the dose may be increased to 100 mg or decreased to 25 mg.
• Do not take more than 1 dose per day.

For Pulmonary Arterial Hypertension (PAH):

• The typical dose is 20 mg, taken three times a day (every 4–6 hours).

How do I take Bigora tablet?

Take Bigora tablet with or without food, but avoid high-fat meals as they delay its effect. Do not consume grapefruit or grapefruit juice to prevent increased side effects. Swallow the tablet with water and follow your doctor’s dosage instructions.

For how long do I take Bigora tablet?

There's no set time someone should use Bigora tablet. How long someone takes it depends on their doctor's advice and how well it works for them.

What disease or symptom is Bigora tablet used for?

Bigora tablet is primarily indicated for the treatment of:

1. Erectile Dysfunction (ED): To help men achieve and maintain an erection during sexual activity.
2. Pulmonary Arterial Hypertension (PAH): To improve exercise capacity and delay disease progression by relaxing blood vessels in the lungs.

How long does it take for Bigora tablet to start working?

Bigora tablet typically starts working within 30 to 60 minutes after taking it. Its effects may vary based on factors like food intake, but it generally requires sexual stimulation to work effectively.

Is Bigora tablet effective?

Evidence supporting Bigora tablet’s effectiveness comes from clinical trials and real-world studies:

• Erectile Dysfunction (ED): Multiple placebo-controlled studies show that Bigora tablet significantly improves erectile function and satisfaction in men with ED. Patients experienced improved ability to achieve and maintain erections during sexual activity.
• Pulmonary Arterial Hypertension (PAH): Studies demonstrate improved exercise capacity and reduced pulmonary pressure, validated by the 6-minute walk test and hemodynamic measurements, confirming its role in PAH treatment.

How do I know if Bigora tablet is working?

The benefits of Bigora tablet are evaluated through:

Patient-reported outcomes: For erectile dysfunction (ED), patient questionnaires like the International Index of Erectile Function (IIEF) assess improvements in erectile function, satisfaction, and quality of life.

Objective clinical measurements: In pulmonary arterial hypertension (PAH), the effectiveness is measured by improvements in exercise capacity (e.g., 6-minute walk test), reduced pulmonary arterial pressure, and hemodynamic parameters.

Trial data: Clinical studies compare Bigora tablet's performance with placebos or other treatments to track improvements in both ED and PAH symptoms.

How does Bigora tablet work?

Bigora tablet works by inhibiting phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP). By blocking PDE5, Bigora tablet increases cGMP levels, leading to relaxation of smooth muscle cells and enhanced blood flow.

• In erectile dysfunction, it improves blood flow to the penis during sexual arousal, facilitating erection.
• In pulmonary arterial hypertension, it relaxes pulmonary blood vessels, lowering blood pressure and improving oxygen delivery.

Who should avoid taking Bigora tablet?

Bigora tablet should not be used by individuals taking nitrates (e.g., nitroglycerin) as it can cause a dangerous drop in blood pressure. It is contraindicated in patients with severe cardiovascular conditions, recent stroke or heart attack, or severe liver or kidney impairment. Caution is needed in people with low blood pressure, dehydration, or eye conditions such as retinitis pigmentosa.

Can I take Bigora tablet with other prescription drugs?

Bigora tablet can interact with several prescription drugs, including:

1. Nitrates (e.g., nitroglycerin): Can cause a dangerous drop in blood pressure.
2. Alpha-blockers (e.g., tamsulosin): May also lower blood pressure and cause dizziness or fainting.
3. Antifungals (e.g., ketoconazole) and antibiotics (e.g., erythromycin): Can increase Bigora tablet levels in the blood, raising the risk of side effects.
4. HIV protease inhibitors (e.g., ritonavir): May enhance Bigora tablet's effects, leading to increased side effects.
5. Rifampin: Can reduce Bigora tablet's effectiveness.

Can Bigora tablet be taken safely while pregnant?

Bigora tablet is classified as Category C by the FDA for pregnancy, which means that animal studies have shown potential risks to the fetus, but there are no well-controlled studies in humans. It should only be used during pregnancy if the potential benefits outweigh the risks. There is limited information on the effects of Bigora tablet on pregnancy, so it is generally not recommended unless prescribed by a healthcare provider for specific conditions.

Can Bigora tablet be taken safely while breastfeeding?

Bigora tablet is excreted in breast milk in small amounts, but its effects on a breastfeeding infant are not well-studied. While it is considered relatively safe for short-term use during lactation, it should only be used if deemed necessary by a healthcare provider. Women who are breastfeeding should consult their doctor before using Bigora tablet to assess the potential risks and benefits.

Is Bigora tablet safe for the elderly?

Older people often have weaker livers, kidneys, or hearts, and may take other medicines. Because of this, doctors need to be careful when deciding on the right dose of a new medicine for them. There haven't been enough older people in medical studies to know for sure if they react to the medicine differently than younger people.

How should I store Bigora tablet?

Bigora tablet should be stored at room temperature, between 68°F and 77°F (20°C to 25°C). Keep the medication in its original container, tightly closed, and away from moisture, heat, and light. It is important to store Bigora tablet out of reach of children and to avoid storing it in the bathroom or areas with high humidity.

Does Bigora tablet make people tired or drowsy?

Bigora tablet does not typically cause tiredness or drowsiness. However, some people report mild fatigue as a side effect.

Does Bigora tablet cause stomach upset?

Yes, stomach upset, indigestion (dyspepsia), or mild nausea are possible side effects of Bigora tablet. Taking it with food (preferably a light meal) may help reduce this.

Does Bigora tablet affect sleep?

Bigora tablet (like Viagra) can sometimes make it hard to sleep. If you have trouble sleeping after taking it, talk to your doctor.

Does Bigora tablet make it hard to think or concentrate?

Bigora tablet is unlikely to impair cognitive function. However, in rare cases, side effects like dizziness or vision changes could temporarily affect concentration.

Does Bigora tablet affect mood?

Bigora tablet does not directly influence mood. However, improved confidence and satisfaction related to its effects may lead to an overall better mood in some individuals.

Does Bigora tablet interfere with sexual function?

No, Bigora tablet is designed to enhance sexual function in men with erectile dysfunction by improving blood flow to the penis. However, it does not increase libido or sexual desire.

Does Bigora tablet affect appetite?

Bigora tablet is not known to significantly affect appetite.

Does Bigora tablet cause weight gain?

No, Bigora tablet does not cause weight gain.

Does Bigora tablet cause headaches?

Bigora tablet (like Viagra) can sometimes cause headaches. A study showed that slightly more people who took it got headaches (46%) than those who took a sugar pill (39%). If you get a headache while taking Bigora tablet, talk to your doctor.

Does Bigora tablet limit driving?

Bigora tablet can make you dizzy, lightheaded, or have blurry vision. These side effects could make it unsafe to drive. If this happens, pull over, stop driving, and call a doctor.

Is it safe to drink alcohol while taking Bigora tablet?

The study showed that taking Viagra (Bigora tablet) along with a moderate amount of alcohol didn't make people's blood pressure drop any more than alcohol alone. Essentially, the combination wasn't more dangerous for blood pressure than alcohol by itself. Nobody experienced dizziness or fainting from a sudden drop in blood pressure when standing up.

Is it safe to drink coffee or tea while taking Bigora tablet?

Yes, it is generally safe to drink coffee or tea while taking Bigora tablet. However, caffeine may exacerbate side effects like headaches or heart palpitations in rare cases.

Is it safe to exercise while taking Bigora tablet?

Yes, it is generally safe to exercise while taking Bigora tablet. However, if you experience side effects like dizziness or low blood pressure, avoid strenuous activity until you feel stable. Consult your doctor if you have any heart conditions before combining Bigora tablet with exercise.

What are the most common side effects of Bigora tablet?

A side effect is an unwanted or unexpected symptom caused by a medicine. For this medicine, common side effects may include nausea, which is feeling sick to your stomach, dizziness, which is feeling lightheaded or unsteady, headache, which is pain in the head, fatigue, which is feeling very tired, and dry mouth, which is a lack of saliva. The frequency of these side effects can vary, but they are generally considered common. It's important to note that when starting a new medicine, people might experience new symptoms that could be coincidental, unrelated, or temporary. These symptoms might also be due to another health issue. Always talk to a healthcare provider before stopping any medicine, as they can provide guidance on managing side effects and ensure your treatment is safe and effective.

Does Bigora tablet have adverse effects?

Adverse effects, which are unwanted or harmful reactions to a medicine, can occur when taking any medication. For this medicine, common adverse effects might include nausea, headache, dizziness, fatigue, and dry mouth. These effects can vary in how often they occur, but they are generally not severe. However, there are rare but serious adverse effects that require immediate medical attention, such as difficulty breathing, severe rash, or swelling of the face and throat. It's crucial to report any new or worsening symptoms to a healthcare provider. Never stop taking a medicine without consulting a healthcare professional, as they can provide guidance on managing side effects and adjusting treatment if necessary.

Is Bigora tablet addictive?

This medicine does not have any known potential for dependence or addiction. It is considered safe in terms of habit-forming properties. Therefore, there is no need to worry about developing a physical or psychological dependence on this medication. However, it is always important to use any medicine as directed by a healthcare professional to ensure safety and effectiveness. If you have any concerns or questions about your medication, it is best to discuss them with your doctor or pharmacist.

Does Bigora tablet have any safety warnings?

This medicine does have safety warnings. One key warning is the risk of allergic reactions, which can occur if you are allergic to any of the ingredients. An allergic reaction can cause symptoms like rash, itching, swelling, severe dizziness, or trouble breathing. If you notice any of these symptoms, seek medical help immediately. Another warning is the potential for liver damage, which can happen if the medicine is taken in high doses or for a long time. Signs of liver damage include yellowing of the skin or eyes, dark urine, or severe stomach pain. If you experience these symptoms, contact your doctor right away. Lastly, this medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. If you feel dizzy or drowsy, avoid these activities to prevent accidents.

Is it safe to stop Bigora tablet?

To determine if it's safe to stop a medicine, first identify its purpose. If it's for managing a chronic condition like hypertension or diabetes, stopping it suddenly can lead to serious health risks, such as uncontrolled blood pressure or blood sugar levels. If the medicine is for symptomatic relief or treating a temporary condition, like an infection, stopping it might lead to a return of symptoms or incomplete treatment. Some medicines can cause withdrawal or rebound symptoms if stopped abruptly, which means symptoms can return worse than before. In some cases, stopping a medicine suddenly can be life-threatening. Therefore, it's crucial to consult with a doctor before making any changes to your medication regimen. They can provide guidance on how to safely stop or adjust your medication.

How do I dispose of Bigora tablet?

If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.

What are Bigora tablet possible harms and risks?

Common side effects of Bigora tablet include headache, flushing, indigestion, nasal congestion, and dizziness. Serious side effects can involve priapism, sudden vision or hearing loss, chest pain, severe hypotension, and allergic reactions. Seek medical help if any severe symptoms occur.