Repaglinide
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DRUG STATUS
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
Unlisted
Pharmaceutical Class
Glinide
Controlled Drug Substance
undefined
Repaglinide
Learn more about this medicine -
Click HereSummary
Repaglinide is used to manage type 2 diabetes in adults. It helps control high blood sugar levels by stimulating insulin release from the pancreas.
Repaglinide works by stimulating the pancreas to produce and release insulin in response to meals. This helps lower post-meal blood sugar spikes and controls overall glucose levels.
Repaglinide is taken orally, typically 15 minutes before a meal. The usual starting dose is 0.5 to 2 mg before meals, depending on blood sugar levels. The dose can be adjusted based on effectiveness and blood sugar levels, with a maximum dose of 16 mg daily.
Common side effects of Repaglinide include hypoglycemia (low blood sugar), headache, back pain, or upper respiratory issues. Severe side effects include signs of allergic reactions such as rash or swelling.
People with type 1 diabetes, diabetic ketoacidosis, or severe liver issues should avoid Repaglinide. Pregnant women should also avoid it as its safety during pregnancy is not established. It can cause dizziness or hypoglycemia, impairing concentration, so avoid driving or operating heavy machinery if you experience these side effects.
Indications and Purpose
What is Repaglinide used for?
Repaglinide is used to treat type 2 diabetes in adults, helping to control high blood sugar levels by stimulating insulin release from the pancreas.
How does Repaglinide work?
Repaglinide works by stimulating the pancreas to produce and release insulin in response to meals. It helps lower post-meal blood sugar spikes and controls overall glucose levels.
Is Repaglinide effective?
Studies show that Repaglinide effectively lowers blood sugar levels after meals by increasing insulin secretion. It is commonly used alongside other diabetes medications.
How does one know if Repaglinide is working?
Repaglinide’s effectiveness is gauged by regular blood sugar monitoring. A stable or reduced fasting and post-meal blood sugar indicate that the medication is working.
Directions for Use
What is the usual dose of Repaglinide?
The usual starting dose is 0.5 to 2 mg before meals, depending on blood sugar levels and the patient's needs. The dose can be adjusted based on effectiveness and blood sugar levels, with a maximum dose of 16 mg daily.
How do I take Repaglinide?
Repaglinide is taken orally, typically 15 minutes before a meal to control post-meal blood sugar spikes. Do not take it if you skip a meal and avoid crushing or breaking the tablets.
For how long do I take Repaglinide?
Repaglinide is usually taken long-term as part of a daily diabetes management plan, though the dose may change over time as blood sugar control improves or worsens.
How long does it take for Repaglinide to start working?
Repaglinide starts working within 15 to 30 minutes of taking the dose, with its effects lasting for 4 to 6 hours.
How should I store Repaglinide?
Store Repaglinide at room temperature, away from moisture and direct sunlight. Keep the medication out of children’s reach and discard expired or unused tablets properly.
Warnings and Precautions
Who should avoid taking Repaglinide?
People with type 1 diabetes, diabetic ketoacidosis, or severe liver issues should avoid Repaglinide. It should not be used without proper blood sugar monitoring.
Can I take Repaglinide with other prescription drugs?
Repaglinide may interact with other diabetes medications, blood pressure drugs, and antifungal medications. Consult your doctor for advice on taking it with other prescriptions.
Can I take Repaglinide with vitamins or supplements?
Repaglinide does not usually interact with vitamins or supplements. However, some supplements, such as biotin or chromium, may affect blood sugar levels, so it's best to consult a doctor before use.
Can Repaglinide be taken safely while pregnant?
Pregnant women should avoid Repaglinide, as its safety during pregnancy has not been established. Insulin is often preferred during pregnancy for blood sugar control. Consult your doctor for guidance.
Can Repaglinide be taken safely while breastfeeding?
Repaglinide passes into breast milk, so it's typically not recommended during breastfeeding. Consult your doctor to explore alternative treatments for managing blood sugar.
Is Repaglinide safe for the elderly?
Elderly patients may be more sensitive to the effects of Repaglinide, particularly the risk of hypoglycemia. Careful dose adjustments and regular blood sugar monitoring are important.
Is it safe to exercise while taking Repaglinide?
Exercise is generally safe while taking Repaglinide. However, physical activity can lower blood sugar, increasing the risk of hypoglycemia, so monitor glucose levels before and after exercise.
Is it safe to drink alcohol while taking Repaglinide?
Alcohol can increase the risk of hypoglycemia when taken with Repaglinide. Drink cautiously, monitor blood sugar closely, and talk to your doctor about alcohol use.
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