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Nifedipine

Hypertension, Angina Pectoris, Variant ... show more

DRUG STATUS

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Approvals

US(FDA), UK(BNF)

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Essential Medicine

YES

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Teratogenicity

Unlisted

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Pharmaceutical Class

Calcium Channel Blocker

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Drug Ingredient

Nifedipine

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Summary

  • Nifedipine is used to treat high blood pressure, also known as hypertension. It can also help prevent future heart disease, heart attacks, and strokes. Additionally, it is used to prevent chest pain caused by a condition called angina. Occasionally, it's used for Raynaud's phenomenon and chilblains, conditions that affect blood flow to the fingers and toes.

  • Nifedipine works by relaxing your blood vessels. This makes it easier for your heart to pump blood, which in turn lowers your blood pressure. It can also reduce the number of angina attacks by increasing the supply of blood and oxygen to your heart.

  • Nifedipine is usually taken orally in the form of extended-release tablets. The usual starting dose for high blood pressure is 30-60 mg once daily, which may be increased depending on your response. For angina, it is typically 30-60 mg once daily.

  • Common side effects of Nifedipine include dizziness, headaches, and swelling in the feet or ankles. Some people may also experience flushing, a rapid heartbeat, or low blood pressure. Rarely, it can lead to heart failure or irregular heart rhythms.

  • You should be cautious when combining Nifedipine with other blood pressure medications, antiarrhythmic drugs, or beta blockers. It's not recommended for people with low blood pressure or severe heart disease unless directed by a doctor. Also, avoid alcohol as it can increase the risk of low blood pressure.

Indications and Purpose

What is Nifedipine used for?

  • High blood pressure (hypertension).
  • Angina (chest pain).
  • It can also be used to treat Raynaud’s disease (narrowing of blood vessels in fingers and toes)

How does Nifedipine work?

Nifedipine works by relaxing the blood vessels, which lowers blood pressure and makes it easier for the heart to pump blood.

Is Nifedipine effective?

Yes, Nifedipine is effective in lowering blood pressure and relieving angina, especially when used consistently as prescribed.

How does one know if Nifedipine is working?

  • Your blood pressure should be lower, and you may experience fewer chest pain episodes (angina).
  • Regular monitoring by your healthcare provider is necessary to check effectiveness.

Directions for Use

What is the usual dose of Nifedipine?

  • The usual starting dose for high blood pressure is 30-60 mg once daily, which may be increased depending on the response.
  • For angina, it is typically 30-60 mg once daily.

How do I take Nifedipine?

  • Oral in the form of extended-release tablets.
  • Take with or without food, and swallow the tablet whole. Do not chew or crush

For how long do I take Nifedipine?

Nifedipine is usually taken long-term, as prescribed by your healthcare provider, depending on your condition.

How long does it take for Nifedipine to start working?

Nifedipine can start working in as little as 20-30 minutes, but its full effect may take a few days to stabilize blood pressure.

How should I store Nifedipine?

Keep the medicine in a cool, dry place away from sunlight. The ideal temperature is between 68°F and 77°F (20°C and 25°C), but it's okay if it gets a little warmer or cooler, between 59°F and 86°F (15°C and 30°C). Use a container that protects it from light and moisture.

Warnings and Precautions

Who should avoid taking Nifedipine?

  • People with low blood pressure (hypotension).
  • Those with severe heart disease or a history of heart failure should avoid it unless directed by a doctor.

Can I take Nifedipine with other prescription drugs?

  • Be cautious when combining Nifedipine with other blood pressure medications, anti-arrhythmic drugs, or beta-blockers.
  • Always inform your doctor about all medications you're taking to avoid interactions.

Can I take Nifedipine with vitamins or supplements?

  • Calcium supplements may affect Nifedipine's effectiveness, so it’s advised to check with your doctor before taking them together.
  • Magnesium or potassium supplements may be safe, but confirm with a healthcare provider.

Can Nifedipine be taken safely while pregnant?

Nifedipine should be used only when absolutely necessary during pregnancy. Consult your doctor for advice.

Can Nifedipine be taken safely while breastfeeding?

Nifedipine is considered safe for breastfeeding in most cases, but consult your doctor to weigh risks and benefits

Is Nifedipine safe for the elderly?

Yes, but caution is advised because elderly individuals may be more sensitive to its effects, especially with lower blood pressure.

Is it safe to exercise while taking Nifedipine?

Exercise is generally safe, but be cautious of dizziness or lightheadedness, particularly if you’re prone to low blood pressure. Always check with your doctor.

Is it safe to drink alcohol while taking Nifedipine?

Drinking alcohol can increase the risk of low blood pressure and should be avoided or consumed with caution.