Nicorandil
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DRUG STATUS
Approvals
UK(BNF)
Essential Medicine
NO
Teratogenicity
Unlisted
Pharmaceutical Class
Arteriolar Vasodilator
Nicorandil
Know More About This Medicine -
Click HereSummary
Nicorandil is used to prevent and manage angina, which is chest pain due to reduced blood flow to the heart.
Nicorandil works by widening the blood vessels, which improves blood flow to the heart and reduces its workload. This helps to prevent angina symptoms like chest pain.
The typical adult dose of Nicorandil is 10-20 mg, taken twice daily. Your doctor may adjust this dose according to your needs. The medicine is usually taken orally, with or without food.
Common side effects of Nicorandil include headaches, flushing, and dizziness. In rare cases, it may cause serious ulcers in the mouth, stomach, or intestines.
Avoid Nicorandil if you have low blood pressure, heart failure due to fluid buildup, or if you're taking other nitrate-based drugs. It's also not suitable for those with a history of ulcers or severe kidney disease. Always consult your doctor before starting this medication.
Indications and Purpose
What is Nicorandil used for?
Nicorandil is used for the prevention and long-term management of stable angina. It is not used for immediate relief during an angina attack.
How does Nicorandil work?
Nicorandil works by relaxing blood vessels, improving blood flow to the heart, and reducing its workload. It acts as both a vasodilator and potassium channel opener.
Is Nicorandil effective?
Yes, clinical studies show that nicorandil effectively reduces chest pain and improves blood flow in patients with angina. It’s especially useful in patients not responding well to other treatments.
How does one know if Nicorandil is working?
Relief from angina symptoms such as chest pain and improved ability to perform physical activities without discomfort indicate the medicine is working. Regular checkups help assess its effectiveness.
Directions for Use
What is the usual dose of Nicorandil?
The typical adult dose is 10–20 mg taken twice daily. For some patients, the doctor may adjust the dose to as low as 5 mg or as high as 40 mg daily. This medicine is not suitable for children.
How do I take Nicorandil?
Take nicorandil exactly as prescribed, usually with water. It can be taken with or without food. Avoid alcohol and follow any dietary advice given by your doctor.
For how long do I take Nicorandil?
Nicorandil is typically taken long-term to manage and prevent angina symptoms. Do not stop the medication without consulting your doctor.
How long does it take for Nicorandil to start working?
Nicorandil usually starts to work within 30–60 minutes of taking a dose, helping to improve blood flow and reduce chest pain symptoms.
How should I store Nicorandil?
Store nicorandil at room temperature, away from direct sunlight and moisture. Keep it in its original packaging and out of reach of children.
Warnings and Precautions
Who should avoid taking Nicorandil?
Avoid nicorandil if you have low blood pressure, heart failure due to fluid buildup, or if you are taking other nitrate-based drugs. It should also not be used by those with a history of ulcers or severe kidney disease.
Can I take Nicorandil with other prescription drugs?
This medicine can interact with nitrate-based drugs, blood pressure medicines, and erectile dysfunction drugs like sildenafil. Inform your doctor about all other medications to prevent complications.
Can I take Nicorandil with vitamins or supplements?
Nicorandil may interact with certain supplements. Always inform your doctor about any vitamins or supplements you’re taking to avoid potential issues.
Can Nicorandil be taken safely while pregnant?
Nicorandil is not usually recommended during pregnancy due to limited safety data. If you're pregnant or planning to conceive, consult your doctor.
Can Nicorandil be taken safely while breastfeeding?
There is insufficient information about nicorandil’s safety while breastfeeding. Consult your doctor before using this medication during nursing.
Is Nicorandil safe for the elderly?
Nicorandil is generally safe for elderly patients but requires careful monitoring due to an increased risk of side effects like dizziness and ulcers. Dose adjustments may be needed.
Is it safe to exercise while taking Nicorandil?
Yes, regular exercise is safe while on nicorandil. Be cautious with strenuous activity if you experience dizziness, and monitor your heart health closely during physical activity.
Is it safe to drink alcohol while taking Nicorandil?
Alcohol may enhance the dizziness or lightheadedness caused by nicorandil. It is best to avoid or limit alcohol consumption while on this medication.
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