Hydrocortisone
Ulcerative Colitis, Congenital Adrenal Hyperplasia ... show more
DRUG STATUS
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
Unlisted
Pharmaceutical Class
Corticosteroid

Hydrocortisone
Learn more about this medicine -
Click HereSummary
Hydrocortisone is used to treat conditions where your body doesn't produce enough of an important hormone called cortisol. This can occur due to problems with your adrenal glands or due to a birth defect. It helps reduce swelling and inflammation in various conditions.
Hydrocortisone is a type of steroid hormone that your body naturally makes. It works by changing how your immune system reacts to things that trigger inflammation or immune responses. It also affects how your body uses energy.
Hydrocortisone is taken orally, with doses ranging from 20mg to 240mg a day, depending on the illness. The exact dose is determined by your doctor. If you've been taking it for a long time, the dose should be reduced slowly under your doctor's guidance.
Common side effects of Hydrocortisone include high blood pressure, fluid retention, swelling, low potassium levels, and weight gain due to increased appetite. It can also cause mood changes, headaches, and gastrointestinal issues like peptic ulcers and nausea.
Hydrocortisone should not be taken if you have a known hypersensitivity to it or if you have systemic fungal infections. Avoid live vaccines while on this medication as it weakens your immune system. Long-term use can lead to eye problems like cataracts and glaucoma.
Indications and Purpose
What is Hydrocortisone used for?
Hydrocortisone is a medicine that replaces a natural hormone your body needs. If your body doesn't make enough of this hormone (cortisol), Hydrocortisone helps to replace it. This hormone is important for many things, and if you're missing it, you can get sick. Hydrocortisone is used to treat conditions where your body doesn't produce enough of this important hormone, either because of a problem with your adrenal glands (which make the hormone) or because of a birth defect.
How does Hydrocortisone work?
Hydrocortisone is a natural hormone our bodies make. It helps reduce swelling and inflammation throughout the body. Doctors use it to replace missing hormones in people who don't make enough, or to treat inflammation in various conditions. It's easily absorbed when taken by mouth and works by changing how our immune system reacts.
Is Hydrocortisone effective?
Hydrocortisone is a medicine that replaces a natural hormone your body needs. It's used when your body doesn't make enough of this hormone itself (adrenocortical insufficiency) or if there's a problem with hormone production from birth (congenital adrenal hyperplasia).
Hydrocortisone is effective in reducing inflammation, modulating immune responses, and managing endocrine deficiencies. Clinical responses depend on the dosage and condition being treated
How does one know if Hydrocortisone is working?
Hydrocortisone helps by making you feel better. Doctors watch how you respond and change the amount you take to find the smallest amount that still works. If you feel better, they slowly lower the dose. I
Effectiveness is monitored by observing symptom improvement, such as reduced inflammation, pain relief, or stabilized hormone levels. Regular follow-ups and lab tests may be required
Directions for Use
What is the usual dose of Hydrocortisone?
Hydrocortisone come in different starting doses for adults, from 20mg to 240mg a day, depending on the illness. The doctor will decide the right dose for you. Kids need close watching if they take it for a long time, to make sure they grow normally. Your dose might change based on how you're feeling and other things about your health. If you've been taking it for a long time, you shouldn't stop suddenly—your doctor will help you slowly reduce the dose.
How do I take Hydrocortisone?
Hydrocortisone tablets should be taken orally as prescribed, with or without food. The exact timing and frequency depend on the condition being treated. For prolonged use, gradual tapering is required to avoid withdrawal
For how long do I take Hydrocortisone?
The duration depends on the specific condition. It can range from short-term use for acute conditions to long-term therapy for chronic diseases. Dosage adjustments are needed during periods of stress or illness.
How long does it take for Hydrocortisone to start working?
The onset of action depends on the condition being treated and the dose but typically occurs within hours after administration.
How should I store Hydrocortisone?
Keep this item at room temperature. The ideal temperature is between 20 and 25 degrees Celsius (that's about 68 to 77 degrees Fahrenheit).
Warnings and Precautions
Who should avoid taking Hydrocortisone?
Hydrocortisone is a powerful medicine, so it needs close watching when you take it. Don't get live vaccines while on it, as it weakens your immune system and might reduce the effectiveness of other vaccines. It can worsen some infections, like those caused by amoeba or fungus, and make measles or chickenpox much more dangerous. High doses can raise blood pressure, cause swelling, and affect your potassium levels. Taking it for a long time can lead to eye problems like cataracts and glaucoma.
- Known hypersensitivity to hydrocortisone or its components.
- Systemic fungal infections.
- Administration of live vaccines during high-dose corticosteroid therapy
Can I take Hydrocortisone with other prescription drugs?
Hydrocortisone, a type of steroid medicine, can interact badly with other drugs. Some drugs make your body get rid of hydrocortisone faster, meaning you might need a higher dose.
Interactions with Other Drugs Phenytoin, rifampin, Ketoconazole and live vaccines.
Hydrocortisone can also affect how your body processes other medicines like aspirin and blood thinners, requiring close monitoring by your doctor to keep you safe.
Can I take Hydrocortisone with vitamins or supplements?
Calcium and vitamin D supplementation may be needed to prevent osteoporosis during long-term use. Potassium supplements might also be necessary to counteract potassium loss.
Can Hydrocortisone be taken safely while pregnant?
Use only if benefits outweigh risks, as it may impair fetal growth and cause hypoadrenalism in newborns if used in high doses.
Can Hydrocortisone be taken safely while breastfeeding?
Use with caution; it is excreted in breast milk. Babies born to mothers who took large amounts of these medicines during pregnancy need to be watched closely for potential hormone problems.
Is Hydrocortisone safe for the elderly?
For older people taking steroid medicines, it's crucial to keep a close eye on the dose. The doctor may need to change it based on how they're feeling, how well their body responds, or if they're stressed. If they've been on the medicine a long time, it needs to be stopped slowly. Steroids can make infections more likely and might increase the chances of eye problems like cataracts or glaucoma. In men, they can also affect fertility.
Is it safe to exercise while taking Hydrocortisone?
Exercise is generally safe but may need to be moderated if muscle weakness, osteoporosis, or adrenal insufficiency is present.
Is it safe to drink alcohol while taking Hydrocortisone?
Avoid excessive alcohol consumption as it may increase the risk of gastrointestinal side effects like ulcers.