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Diltiazem

Supraventricular Tachycardia, Variant Angina Pectoris ... show more

DRUG STATUS

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Approvals

US(FDA), UK(BNF)

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Essential Medicine

YES

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Teratogenicity

Unlisted

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Pharmaceutical Class

Calcium Channel Blocker

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Drug Ingredient

Diltiazem

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Summary

  • Diltiazem is used to treat high blood pressure, chest pain known as angina, and certain abnormal heart rhythms like atrial fibrillation or flutter.

  • Diltiazem works by blocking calcium channels in your heart and blood vessels. This relaxes and widens your blood vessels, lowers your heart rate, and reduces the workload on your heart. This improves blood flow and helps control abnormal heart rhythms.

  • The usual dose for adults is 30-60 mg taken 3-4 times daily, or a once-daily dose of 120-360 mg, depending on the condition being treated. Diltiazem should be taken orally, with or without food. It is typically in tablet or extended-release capsule form.

  • Common side effects of Diltiazem include dizziness, headache, constipation, and swelling. Some people may also experience gastrointestinal issues such as nausea or abdominal discomfort.

  • Diltiazem should not be taken by those with severe low blood pressure, heart block, or certain arrhythmias. Pregnant or breastfeeding women should consult their doctor before using this medication. It may cause dizziness or tiredness which could impair your ability to drive or operate machinery.

Indications and Purpose

What is Diltiazem used for?

Diltiazem is used to treat high blood pressure (hypertension), chest pain (angina), and certain abnormal heart rhythms, like atrial fibrillation or flutter. It helps to relax the blood vessels and reduce heart strain.

How does Diltiazem work?

Diltiazem works by blocking calcium channels in the heart and blood vessels, relaxing and widening blood vessels, lowering heart rate, and reducing the heart’s workload. This improves blood flow and prevents abnormal heart rhythms.

Is Diltiazem effective?

Yes, diltiazem is effective in reducing blood pressure, controlling heart rate, and preventing chest pain. It has been shown to help manage conditions like high blood pressure and certain arrhythmias, improving overall heart function.

How does one know if Diltiazem is working?

You may notice symptoms such as less chest pain, improved exercise tolerance, and more stable blood pressure. Your healthcare provider will monitor your blood pressure and heart function through regular check-ups.

Directions for Use

What is the usual dose of Diltiazem?

The usual dose for adults is 30–60 mg, taken 3–4 times daily, or a once-daily dose of 120–360 mg, depending on the condition being treated. Children’s doses depend on the child’s specific condition.

How do I take Diltiazem?

Diltiazem should be taken orally with or without food. It is typically in tablet or extended-release capsule form. Take it regularly and at the same time each day to help remember.

For how long do I take Diltiazem?

Diltiazem is typically taken long-term for managing blood pressure or heart conditions. The duration of treatment depends on the patient's response and their doctor’s recommendations.

How long does it take for Diltiazem to start working?

Diltiazem begins to work within a few hours to reduce blood pressure and relieve chest pain. It may take a few weeks for optimal benefits, especially for long-term heart conditions.

How should I store Diltiazem?

Keep the medicine in a cool, dry place, between 68°F to 77°F. It's okay if it gets a little warmer or cooler, between 59°F to 86°F. Don't let it get too hot (above 86°F) or too humid. Keep the medicine in a container that's sealed and doesn't let light in.

Warnings and Precautions

Who should avoid taking Diltiazem?

Diltiazem should not be taken by those with severe low blood pressure, heart block, or certain arrhythmias. Pregnant or breastfeeding women should consult their doctor before using this medication.

Can I take Diltiazem with other prescription drugs?

Diltiazem may interact with drugs like beta-blockers, other blood pressure medications, or antiarrhythmic drugs. It’s crucial to inform your healthcare provider of all medications, including over-the-counter drugs, that you're taking.

Can I take Diltiazem with vitamins or supplements?

Certain supplements, like those containing calcium or magnesium, may interfere with diltiazem's effectiveness. Always consult your doctor before using supplements along with this medication.

Can Diltiazem be taken safely while pregnant?

Diltiazem should be used in pregnancy only if clearly necessary. It is categorized as a Category C medication, meaning its risks to the fetus are not fully known. Consult your doctor before use during pregnancy.

Can Diltiazem be taken safely while breastfeeding?

Diltiazem passes into breast milk in small amounts. While it is considered generally safe to use while breastfeeding, it’s important to consult your doctor to weigh the benefits against any potential risks to your baby.

Is Diltiazem safe for the elderly?

Elderly patients are generally more sensitive to diltiazem. They may need lower doses and close monitoring, especially if they have kidney or liver problems. Adjustments to the dosage may be needed.

Is it safe to exercise while taking Diltiazem?

Exercise is generally safe with diltiazem, but if you're feeling fatigued, dizzy, or have low blood pressure, take extra precautions. Discuss your exercise routine with your healthcare provider to ensure it's safe for your specific heart condition.

Is it safe to drink alcohol while taking Diltiazem?

Drinking alcohol with diltiazem can increase the risk of side effects such as dizziness, lightheadedness, or a drop in blood pressure. It’s best to limit alcohol intake or avoid it while on this medication. Discuss with your doctor for personalized advice.