Dicloxacillin
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DRUG STATUS
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
Unlisted
Pharmaceutical Class
Penicillin-class Antibacterial
Controlled Drug Substance
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Dicloxacillin
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Click HereSummary
Dicloxacillin is an antibiotic used to treat infections caused by certain bacteria, particularly penicillinase-producing staphylococci. It is used to treat conditions such as skin infections, respiratory tract infections, and bone infections.
Dicloxacillin works by inhibiting the synthesis of bacterial cell walls, which are essential for their survival. It is a penicillinase-resistant antibiotic, meaning it can effectively target bacteria that produce an enzyme called penicillinase, which would otherwise inactivate other penicillins. This action leads to the death of the bacteria and helps clear the infection.
For adults, the usual dose of Dicloxacillin is 125 mg every 6 hours for mild to moderate infections and 250 mg every 6 hours for severe infections. For children, the dose is typically 12.5 mg/kg/day in equally divided doses every 6 hours for mild to moderate infections and 25 mg/kg/day for severe infections. Dicloxacillin should be taken on an empty stomach.
Common side effects of Dicloxacillin include nausea, vomiting, diarrhea, and abdominal pain. Serious adverse effects can include allergic reactions such as rash, itching, hives, and difficulty breathing.
Dicloxacillin should not be used by individuals who are allergic to penicillins. It may also cause antibiotic-associated diarrhea which can be severe. Patients with a history of allergies or asthma should use it cautiously. Always inform your doctor of any allergies or medical conditions before starting Dicloxacillin.
Indications and Purpose
What is Dicloxacillin used for?
Dicloxacillin is indicated for the treatment of infections caused by penicillinase-producing staphylococci, which are resistant to other penicillins. It is used to treat conditions such as skin infections, respiratory tract infections, and bone infections, among others, where these bacteria are the causative agents.
How does Dicloxacillin work?
Dicloxacillin works by inhibiting the synthesis of bacterial cell walls, which are essential for their survival. It is a penicillinase-resistant antibiotic, meaning it can effectively target bacteria that produce an enzyme called penicillinase, which would otherwise inactivate other penicillins. This action leads to the death of the bacteria and helps clear the infection.
Is Dicloxacillin effective?
Dicloxacillin is a penicillin antibiotic that works by killing bacteria. It is effective against infections caused by penicillinase-producing staphylococci, which are resistant to other penicillins. Clinical studies and microbiological tests have shown its effectiveness in treating these types of bacterial infections.
How does one know if Dicloxacillin is working?
The benefit of dicloxacillin is evaluated through clinical response and laboratory tests. Doctors may order lab tests to check the effectiveness of the treatment and monitor for any side effects. Regular follow-ups with your healthcare provider are important to ensure the medication is working as intended.
Directions for Use
What is the usual dose of Dicloxacillin?
For adults, the usual dose of dicloxacillin is 125 mg every 6 hours for mild to moderate infections and 250 mg every 6 hours for severe infections. For children, the dose is typically 12.5 mg/kg/day in equally divided doses every 6 hours for mild to moderate infections and 25 mg/kg/day for severe infections. Always follow your doctor's specific instructions.
How do I take Dicloxacillin?
Dicloxacillin should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal. It should be taken with at least 4 ounces (120 mL) of water while sitting or standing up. Avoid lying down immediately after taking the medication. Follow your doctor's instructions carefully and complete the full course of treatment.
For how long do I take Dicloxacillin?
The duration of dicloxacillin treatment depends on the type and severity of the infection. It is important to complete the full course as prescribed by your doctor, even if you feel better before finishing the medication. Stopping early can lead to a return of the infection and increase the risk of antibiotic resistance.
How long does it take for Dicloxacillin to start working?
Dicloxacillin begins to work shortly after ingestion, with peak blood levels achieved in 1 to 1.5 hours. However, the time it takes to notice improvement in symptoms can vary depending on the type and severity of the infection. Always complete the full course of treatment as prescribed by your doctor.
How should I store Dicloxacillin?
Store dicloxacillin capsules at room temperature, away from excess heat and moisture. Keep the medication in its original container, tightly closed, and out of reach of children. Do not store it in the bathroom. Proper storage ensures the medication remains effective and safe to use.
Warnings and Precautions
Who should avoid taking Dicloxacillin?
Dicloxacillin should not be used by individuals who are allergic to penicillins or any of its components. Serious allergic reactions, including anaphylaxis, can occur. It may also cause antibiotic-associated diarrhea, which can be severe. Patients with a history of allergies or asthma should use it cautiously. Always inform your doctor of any allergies or medical conditions before starting dicloxacillin.
Can I take Dicloxacillin with other prescription drugs?
Dicloxacillin may interact with tetracycline antibiotics, reducing their effectiveness. It can also affect the anticoagulant response to warfarin, requiring careful monitoring of prothrombin times. Probenecid can increase and prolong serum penicillin levels. Always inform your doctor of all medications you are taking to avoid potential interactions.
Can I take Dicloxacillin with vitamins or supplements?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Dicloxacillin be taken safely while pregnant?
Dicloxacillin should be used during pregnancy only if clearly needed. Animal studies have not shown harm to the fetus, but there are no adequate human studies. Always consult your doctor to weigh the benefits and risks before using dicloxacillin during pregnancy.
Can Dicloxacillin be taken safely while breastfeeding?
Dicloxacillin is excreted in breast milk, so caution is advised when administering it to nursing mothers. Consult your doctor to discuss the potential risks and benefits before using dicloxacillin while breastfeeding.
Is Dicloxacillin safe for the elderly?
For elderly patients, dicloxacillin should be used with caution, starting at the lower end of the dosing range. This is due to the increased likelihood of decreased liver, kidney, or heart function, and the presence of other medical conditions or medications. Regular monitoring and adjustments may be necessary to ensure safety and effectiveness.
Is it safe to exercise while taking Dicloxacillin?
Dicloxacillin does not typically limit the ability to exercise. However, if you experience any side effects such as joint pain or muscle pain, it may affect your ability to exercise comfortably. If you notice any unusual symptoms while exercising, consult your doctor for advice.
Is it safe to drink alcohol while taking Dicloxacillin?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
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