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Dexlansoprazole

Peptic Esophagitis, Gastroesophageal Reflux ... show more

DRUG STATUS

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Approvals

US(FDA), UK(BNF)

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Essential Medicine

NO

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Teratogenicity

Unlisted

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Pharmaceutical Class

Proton Pump Inhibitor

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Drug Ingredient

Dexlansoprazole

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Summary

  • Dexlansoprazole is used to treat conditions like gastroesophageal reflux disease (GERD), erosive esophagitis, stomach ulcers, and acid reflux. It helps relieve symptoms such as heartburn, difficulty swallowing, and irritation in the esophagus.

  • Dexlansoprazole works by blocking proton pumps in your stomach. These pumps are responsible for producing stomach acid. By reducing acid levels, Dexlansoprazole helps prevent damage to the esophagus and stomach lining and alleviates symptoms of acid reflux.

  • Dexlansoprazole is typically taken once daily, at least 30 minutes before a meal. The usual dose for GERD or erosive esophagitis is 30 mg to 60 mg. If you can't swallow the capsule, you can open it and sprinkle the contents on applesauce.

  • Common side effects of Dexlansoprazole include headache, diarrhea, abdominal pain, and nausea. Serious side effects can include allergic reactions, low magnesium levels, and bone fractures with long-term use.

  • People allergic to Dexlansoprazole or any proton pump inhibitors should avoid it. It should also be used with caution in individuals with liver disease, low magnesium levels, or a history of stomach issues. Pregnant women should use it only if absolutely necessary and breastfeeding mothers should consult a doctor before use.

Indications and Purpose

What is Dexlansoprazole used for?

Dexlansoprazole is used to treat GERD, a condition where stomach acid irritates the esophagus, as well as stomach ulcers, acid reflux, and damage to the esophagus from stomach acid.

How does Dexlansoprazole work?

Dexlansoprazole works by blocking proton pumps in the stomach, which are responsible for producing stomach acid. By reducing acid levels, it helps prevent damage to the esophagus and stomach lining and alleviates symptoms of acid reflux.

Is Dexlansoprazole effective?

Dexlansoprazole is effective in reducing acid reflux, healing esophageal damage, and providing long-term symptom relief in people with GERD and other acid-related stomach conditions.

How does one know if Dexlansoprazole is working?

If the medicine is working, symptoms like heartburn, acid reflux, and swallowing difficulties should improve. Your doctor may also perform tests to check the healing of the esophagus or stomach ulcers.

Directions for Use

What is the usual dose of Dexlansoprazole?

For GERD or erosive esophagitis, the usual dose is 30 mg to 60 mg once a day. The dose for healing esophageal ulcers or other conditions may vary based on individual needs and doctor recommendations.

How do I take Dexlansoprazole?

Dexlansoprazole is usually taken once daily, at least 30 minutes before a meal. Swallow the capsule whole. If unable to swallow it, you can open the capsule and sprinkle the contents on applesauce. Follow your doctor’s instructions carefully.

For how long do I take Dexlansoprazole?

Dexlansoprazole may be taken for a short time, typically 4–8 weeks, for conditions like GERD. For long-term issues, it may be taken as needed under a doctor’s supervision to manage symptoms and prevent recurrence.

How long does it take for Dexlansoprazole to start working?

Dexlansoprazole may take 1-4 days to show its effects in reducing acid levels. However, symptom relief, such as reduced heartburn, may be noticed within a few hours after the first dose.

How should I store Dexlansoprazole?

Store dexlansoprazole in a cool, dry place, away from moisture and direct sunlight. Keep the medicine in its original bottle and out of the reach of children.

Warnings and Precautions

Who should avoid taking Dexlansoprazole?

People allergic to dexlansoprazole or any PPIs should avoid it. It should also be used with caution in individuals with liver disease, low magnesium levels, or a history of stomach issues.

Can I take Dexlansoprazole with other prescription drugs?

Dexlansoprazole can interact with other drugs, including blood thinners (like warfarin) and antifungal medications. Always inform your doctor about all prescription and over-the-counter medications you are taking to prevent interactions.

Can I take Dexlansoprazole with vitamins or supplements?

Dexlansoprazole can interact with certain vitamins and supplements, especially those containing magnesium or calcium, due to its effect on stomach acidity. Consult your healthcare provider for guidance on taking supplements while on this medication.

Can Dexlansoprazole be taken safely while pregnant?

Dexlansoprazole is classified as pregnancy category C, meaning it should only be used during pregnancy if absolutely necessary. Always consult your doctor before taking it during pregnancy.

Can Dexlansoprazole be taken safely while breastfeeding?

Dexlansoprazole is excreted in breast milk in small amounts. Though it is generally considered safe for breastfeeding mothers, consult your doctor before use to ensure safety for you and your baby.

Is Dexlansoprazole safe for the elderly?

Elderly patients may be more sensitive to the effects of dexlansoprazole, especially with long-term use. Dose adjustments may be necessary. It's important to discuss risks with your doctor.

Is it safe to exercise while taking Dexlansoprazole?

Exercise is generally safe while taking dexlansoprazole. However, if you experience any discomfort, such as pain or dizziness, you should rest and consult your doctor before resuming physical activity.

Is it safe to drink alcohol while taking Dexlansoprazole?

While moderate alcohol consumption is generally safe, alcohol can irritate your stomach and esophagus, which may interfere with the effectiveness of dexlansoprazole in treating acid reflux or GERD.