Bisacodyl
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DRUG STATUS
Approvals
US(FDA), UK(BNF)
Essential Medicine
NO
Teratogenicity
N/A
Pharmaceutical Class
Stimulant Laxative
Bisacodyl
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Click HereSummary
Bisacodyl is primarily used to treat constipation, including occasional constipation. It is also used to empty the bowels before medical procedures like colonoscopies or surgeries to ensure a clear colon for better examination.
Bisacodyl works by stimulating the muscles in the intestines, promoting bowel movement and helping to clear stool. It increases the rhythmic contraction of muscles that move stool through the digestive tract and retains water in the intestines, softening the stool for easier elimination.
For adults, the usual dosage of Bisacodyl is 5-15 mg orally taken once a day, usually at bedtime. If using the suppository form, 10 mg is typically used once a day. It should be taken with a full glass of water and the oral tablets should not be chewed or crushed. Suppositories should be inserted into the rectum for effective use.
Common side effects of Bisacodyl include abdominal cramps, bloating, nausea, and diarrhea. These are typically mild and temporary. However, significant adverse effects, though rare, can include dehydration, electrolyte imbalances, and chronic laxative dependence if used for long periods.
Bisacodyl should not be used by individuals with gastrointestinal issues such as bowel obstruction, acute abdominal pain, appendicitis, or inflammatory bowel disease. It should also be avoided in cases of severe dehydration or electrolyte imbalances. Prolonged use can lead to dependency and it is not recommended for children under 6 years old without a doctor's guidance.
Indications and Purpose
What is Bisacodyl used for?
Bisacodyl is primarily indicated for the treatment of constipation, including occasional constipation. It is also used to empty the bowels before medical procedures, such as colonoscopies or surgeries, to ensure a clear colon for better examination. It is not intended for long-term use but can provide relief for temporary bowel irregularities.
How does Bisacodyl work?
Bisacodyl works by stimulating the muscles in the walls of the intestines, promoting peristalsis (the rhythmic contraction of muscles that move stool through the digestive tract). This action helps to increase bowel movement and accelerate the passage of stool. It also helps to retain water in the intestines, softening the stool for easier elimination.
Is Bisacodyl effective?
Clinical studies show that Bisacodyl is effective in relieving constipation and preparing the bowel for medical procedures. Research demonstrates that it stimulates intestinal motility and helps soften stool, providing relief within 6 to 12 hours when taken orally and faster when used as a suppository. Its effectiveness is well-established for short-term use, offering reliable results in improving bowel movements.
How does one know if Bisacodyl is working?
The benefit of Bisacodyl is evaluated by assessing its effectiveness in relieving constipation or clearing the bowels for procedures. This is typically measured by the time it takes to produce a bowel movement, stool consistency, and overall symptom relief. For bowel preparation, the success is determined by the clarity of the colon during medical procedures, such as a colonoscopy.
Directions for Use
What is the usual dose of Bisacodyl?
For adults and children aged 12 years and over, the usual dose is 1 to 3 tablets in a single daily dose. For children aged 6 to under 12 years, the recommended dose is 1 tablet in a single daily dose. For children under 6 years, it is advised to consult a doctor for the appropriate dosage.
How do I take Bisacodyl?
Bisacodyl should be taken on an empty stomach, preferably at bedtime, for maximum effectiveness. It can be taken with or without food, but avoid taking it with dairy products or antacids as they may interfere with the action of the medication. It's important not to chew or crush the oral tablets, and the suppository should be inserted into the rectum for proper use.
For how long do I take Bisacodyl?
Bisacodyl is typically used for short-term relief of constipation. It is not recommended to use a laxative for more than 1 week unless directed by a doctor. Prolonged use can lead to dependency or worsen constipation.
How long does it take for Bisacodyl to start working?
Bisacodyl typically starts working within 6 to 12 hours when taken orally. If used as a suppository, it may work within 15 to 60 minutes for quicker relief. The time it takes to produce a bowel movement can vary depending on the individual and the form used.
How should I store Bisacodyl?
Store the Bisacodyl at room temperature (77°F), but it can be stored between 59°-86°F if needed. Keep it away from extreme moisture.
Warnings and Precautions
Who should avoid taking Bisacodyl?
Bisacodyl should not be used by individuals with gastrointestinal issues such as bowel obstruction, acute abdominal pain, appendicitis, or inflammatory bowel disease. It should also be avoided in cases of severe dehydration or electrolyte imbalances. Prolonged use can lead to dependency, and it is not recommended for children under 6 years old without a doctor's guidance. Always follow the prescribed duration of use.
Can I take Bisacodyl with other prescription drugs?
Bisacodyl can interact with certain prescription drugs. For example, antacids, H2 blockers, or proton pump inhibitors can alter Bisacodyl's effectiveness by increasing stomach pH, potentially reducing its action. Diuretics or corticosteroids may increase the risk of electrolyte imbalances when used with Bisacodyl. Always inform a healthcare provider of any medications being taken to avoid harmful interactions.
Can I take Bisacodyl with vitamins or supplements?
Bisacodyl may interact with certain vitamins and supplements, particularly those affecting electrolyte balance. Long-term use can lead to dehydration and a loss of electrolytes like potassium and magnesium, which can affect the effectiveness of supplements. It’s important to monitor electrolyte levels and consult a healthcare provider if taking vitamins or supplements, especially those that contain potassium, calcium, or magnesium.
Can Bisacodyl be taken safely while pregnant?
Bisacodyl is classified as a Category C drug during pregnancy, meaning its safety has not been fully established. Animal studies suggest potential risks, but there is limited data on its effects in humans. It should only be used during pregnancy if the benefits outweigh the risks, and it’s best to consult a healthcare provider before use, especially in the first trimester.
Can Bisacodyl be taken safely while breastfeeding?
Bisacodyl is considered safe during lactation, as only small amounts are excreted in breast milk. However, prolonged use or overuse could lead to dehydration or electrolyte imbalances in both the mother and baby. It’s recommended to use Bisacodyl sparingly and for short-term relief while breastfeeding, and to consult a healthcare provider for guidance if concerned.
Is Bisacodyl safe for the elderly?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Is it safe to exercise while taking Bisacodyl?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Is it safe to drink alcohol while taking Bisacodyl?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
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