Aspirin
Rheumatoid Arthritis, Pain ... show more
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DRUG STATUS
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
Unlisted
Pharmaceutical Class
Nonsteroidal Anti-inflammatory Drug and Platelet Aggregation Inhibitor
Aspirin
Learn more about this medicine -
Click HereSummary
Aspirin is used for pain relief, reducing inflammation, and preventing blood clots. It can help with minor aches and pains like headaches, muscle aches, arthritis, and toothaches. It's also used for cardiovascular protection in people at risk of heart attacks, strokes, or blood clots.
Aspirin works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2) which help produce prostaglandins, chemicals that cause inflammation, pain, and fever. By blocking these, Aspirin reduces pain, inflammation, and prevents blood platelets from clumping together, reducing the risk of blood clots.
Aspirin is typically taken orally with a full glass of water, with or without food. It usually starts working within 30 minutes to 1 hour after administration. Always follow your doctor's guidance for proper use.
Aspirin can cause gastrointestinal issues like stomach ulcers, bleeding or irritation. It can also increase the risk of internal bleeding, especially when combined with blood thinners. Some people might experience side effects like stomach upset or fluid retention.
Aspirin should be avoided by individuals who are allergic to it, have a history of gastrointestinal bleeding or ulcers, certain bleeding disorders, or are pregnant. It should also be avoided in children under 16 with viral infections due to the risk of Reyes syndrome. Always consult your doctor before taking Aspirin.
Indications and Purpose
What is Aspirin used for?
Aspirin is indicated for relieving pain and inflammation in conditions like arthritis, reducing fever, and preventing heart attacks and strokes in individuals at risk. It is also used in certain rheumatologic conditions and to prevent complications in specific heart conditions.
How does Aspirin work?
Aspirin works by inhibiting the enzyme cyclooxygenase, which reduces the production of prostaglandins and thromboxanes. This action helps decrease inflammation, pain, fever, and blood clot formation.
Is Aspirin effective?
Aspirin is effective in relieving pain, reducing fever, and preventing blood clots. It works by inhibiting the production of substances that cause inflammation and clotting. Its effectiveness in preventing heart attacks and strokes in certain individuals is well-documented.
How does one know if Aspirin is working?
The benefit of aspirin is evaluated by its effectiveness in relieving symptoms like pain and fever, and in preventing cardiovascular events. Regular medical check-ups and monitoring of symptoms help assess its ongoing benefit and safety for the individual.
Directions for Use
What is the usual dose of Aspirin?
For adults, the usual dose of aspirin for pain relief is 300-1000 mg every 4 to 6 hours, not exceeding 4 grams per day. For children, aspirin is generally not recommended due to the risk of Reye's syndrome, but if prescribed, the dose should be determined by a doctor.
How do I take Aspirin?
Aspirin can be taken with or without food, but taking it with food or a full glass of water may help reduce stomach upset. There are no specific food restrictions, but avoid alcohol to reduce the risk of stomach bleeding.
For how long do I take Aspirin?
Aspirin can be used for short-term relief of pain or fever, typically not exceeding 10 days for pain or 3 days for fever without consulting a doctor. For cardiovascular protection, it may be used long-term as prescribed by a healthcare provider.
How long does it take for Aspirin to start working?
Aspirin typically starts working within 30 minutes to 1 hour after ingestion for pain relief. For cardiovascular protection, its effects on blood clotting can begin within a few hours.
How should I store Aspirin?
Store aspirin in its original container, tightly closed, at room temperature, away from excess heat and moisture. Keep it out of reach of children. Dispose of tablets with a strong vinegar smell, as this indicates they may have degraded.
Warnings and Precautions
Who should avoid taking Aspirin?
Aspirin should not be used by individuals with allergies to it, those with bleeding disorders, or those who have had stomach ulcers. It should be used cautiously in people with asthma or liver and kidney issues. Pregnant women should avoid high doses, especially in the third trimester.
Can I take Aspirin with other prescription drugs?
Aspirin can interact with blood thinners like warfarin, increasing bleeding risk. It may also interact with NSAIDs, certain diabetes medications, and ACE inhibitors. Always inform your doctor about all medications you are taking to avoid harmful interactions.
Can I take Aspirin with vitamins or supplements?
From all available and reliable information, there is no confirmed data on this. Please consult a doctor for personalized advice.
Can Aspirin be taken safely while pregnant?
Low-dose aspirin may be used during pregnancy under medical supervision, but doses above 81 mg can harm the fetus, especially after 20 weeks. High doses can cause complications during delivery. Pregnant women should consult their doctor before using aspirin.
Can Aspirin be taken safely while breastfeeding?
Aspirin is generally not recommended while breastfeeding due to the risk of Reye's syndrome in infants. If necessary, low doses may be used under medical supervision. Consult your doctor for personalized advice.
Is Aspirin safe for the elderly?
Elderly patients are more susceptible to the adverse effects of aspirin, such as gastrointestinal bleeding and kidney issues. They should use aspirin under medical supervision, especially if they have a history of ulcers or are taking other medications that increase bleeding risk.
Is it safe to exercise while taking Aspirin?
Aspirin does not typically limit the ability to exercise. However, if you experience any side effects like dizziness or stomach pain, it may affect your ability to exercise comfortably. Consult your doctor if you have concerns about exercising while taking aspirin.
Is it safe to drink alcohol while taking Aspirin?
Drinking alcohol while taking aspirin can increase the risk of stomach bleeding. If you consume three or more alcoholic drinks every day, consult your doctor before using aspirin. Occasional or moderate drinking may still pose a risk, so it's best to discuss with a healthcare provider.
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