Acamprosate
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DRUG STATUS
Approvals
US(FDA), UK(BNF)
Essential Medicine
YES
Teratogenicity
N/A
Pharmaceutical Class
undefined
Acamprosate
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Click HereSummary
Acamprosate is used to help individuals recovering from alcohol dependence maintain sobriety. It works best when combined with counseling and social support.
Acamprosate works by calming the brain and fixing the chemical imbalance caused by long-term alcohol use. This helps reduce cravings and makes it easier to avoid alcohol.
Acamprosate is typically taken as delayed-release tablets three times daily. It can be taken with or without food. The specific dose depends on the doctor's prescription.
Common side effects include diarrhea, dizziness, and upset stomach. Rare but serious issues like numbness, rash, or severe allergic reactions require immediate medical attention.
Acamprosate should be avoided by individuals allergic to it, pregnant or breastfeeding women, or those with severe kidney disease. Use caution if you have a history of depression or suicidal thoughts.
Indications and Purpose
What is Acamprosate used for?
Acamprosate is indicated for helping individuals recovering from alcohol dependence maintain sobriety. It is most effective when used with therapy and support systems to manage cravings and prevent relapse.
How does Acamprosate work?
Acamprosate is a medicine that helps people stay away from alcohol after they’ve stopped drinking. It works by calming the brain and fixing the chemical imbalance caused by long-term alcohol use. This helps reduce cravings and makes it easier to avoid alcohol. It doesn’t stop withdrawal symptoms but supports your brain in recovery. For best results, it’s used with therapy and support groups.
Is Acamprosate effective?
Clinical studies show that acamprosate reduces the risk of returning to heavy drinking when combined with counseling and support. It works best in individuals who have already stopped drinking.
How does one know if Acamprosate is working?
A decrease in alcohol cravings and maintaining abstinence from drinking are signs that acamprosate is effective. Regular follow-ups with your doctor help track progress.
Directions for Use
What is the usual dose of Acamprosate?
Acamprosate is typically taken as delayed-release tablets, three times daily. Adults usually take it with or without food, but specific doses depend on the doctor’s prescription. It’s essential to take it at the same time daily to ensure consistent levels in the body.
How do I take Acamprosate?
Take acamprosate exactly as prescribed by your doctor, around the same time daily. Swallow the tablets whole without splitting or crushing them. It can be taken with or without food, and no special diet is required unless instructed otherwise by your doctor.
For how long do I take Acamprosate?
Continue acamprosate for as long as prescribed, even if you feel the urge to drink has reduced. Stopping without consulting your doctor may increase the risk of relapse. Consistent use, along with counseling, improves long-term outcomes.
How long does it take for Acamprosate to start working?
The medication starts acting on the brain relatively quickly to stabilize its chemistry. However, noticeable effects like reduced cravings may take a few weeks, depending on individual response.
How should I store Acamprosate?
Store acamprosate in its original container at room temperature, away from heat, moisture, and light. Keep it out of reach of children and dispose of unused medicine properly.
Warnings and Precautions
Who should avoid taking Acamprosate?
Acamprosate should be avoided by individuals allergic to it, pregnant or breastfeeding women, or those with severe kidney disease. Use caution if you have a history of depression or suicidal thoughts.
Can I take Acamprosate with other prescription drugs?
Acamprosate may interact with certain medications, such as antidepressants. Discuss all current medications with your doctor to avoid adverse effects or reduced efficacy.
Can I take Acamprosate with vitamins or supplements?
Some vitamins or supplements, especially mood-altering ones, may interact with acamprosate. Always inform your doctor about any supplements you are taking.
Can Acamprosate be taken safely while pregnant?
Its safety during pregnancy and breastfeeding is unclear. Use only if absolutely necessary and under close supervision by your doctor.
Can Acamprosate be taken safely while breastfeeding?
Its safety during pregnancy and breastfeeding is unclear. Use only if absolutely necessary and under close supervision by your doctor.
Is Acamprosate safe for the elderly?
Acamprosate is safe for the elderly when prescribed carefully, particularly if kidney function is monitored. A doctor’s guidance is crucial in older adults.
Is it safe to exercise while taking Acamprosate?
Acamprosate does not typically limit the ability to exercise and is generally well-tolerated. Mild side effects like dizziness or weakness may occur in some individuals but are uncommon. Most people can safely engage in physical activity while taking acamprosate.
Is it safe to drink alcohol while taking Acamprosate?
Drinking alcohol while taking acamprosate does not cause harmful interactions or safety risks. However, it can reduce the medication's effectiveness in supporting abstinence, as acamprosate is designed to help maintain recovery. To achieve the best results, it is recommended to avoid alcohol while on this medication.
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