Methimazole

Thyroid Crisis, Goiter

Drug Status

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Government Approvals

US(FDA)

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WHO Essential Medicine

YES

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Known Teratogen

Possible

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Pharmaceutical Class

Thyroid Hormone Synthesis Inhibitor

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Controlled Drug Substance

NO

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Drug Ingredient

Methimazole

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Summary

  • Methimazole is used to treat an overactive thyroid, also known as hyperthyroidism. This condition can be caused by Graves' disease or toxic multinodular goiter, which are disorders where the thyroid gland produces too much thyroid hormone.

  • Methimazole works by stopping your body from making too much thyroid hormone. It doesn't get rid of thyroid hormone that's already in your body, it only prevents your body from making more.

  • Methimazole is usually taken three times a day with food. Adults start with 15mg daily for mild cases, increasing to 30-40mg for moderate and 60mg for severe cases. The usual daily range is 5-15mg.

  • The most common side effect of Methimazole is an upset stomach. Less common but serious side effects include problems with blood cell production, fever, liver inflammation, and inflammation of blood vessels.

  • Methimazole can harm a developing baby during the first three months of pregnancy. It can also cause a dangerously low white blood cell count and damage the liver. Don't take it if you're allergic to it.

Indications and Purpose

Directions for Use

Warnings and Precautions