Levomilnacipran
Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Serotonin and Norepinephrine Reuptake Inhibitor
Controlled Drug Substance
No

levomilnacipran
Summary
Levomilnacipran is used to treat major depressive disorder, which is a condition characterized by persistent sadness and a loss of interest in activities. It helps improve mood and emotional balance.
Levomilnacipran works by affecting neurotransmitters, which are chemicals in the brain that help regulate mood. It belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors, which increase the levels of these neurotransmitters to improve mood and reduce symptoms of depression.
The usual starting dose of Levomilnacipran for adults is 20 mg once daily, which may be increased to 40 mg based on response and tolerance. The maximum recommended dose is 120 mg per day. It is taken orally, preferably in the morning, with or without food.
Common side effects of Levomilnacipran include nausea, headache, and increased sweating, which are unwanted reactions that can occur when taking a medication. These side effects affect less than 10% of users and are usually mild to moderate in severity.
Levomilnacipran can increase blood pressure, so regular monitoring is necessary. It should not be used if you have uncontrolled narrow-angle glaucoma, which is a condition where fluid pressure in the eye increases. Always consult your doctor about any health concerns before using Levomilnacipran.
Indications and Purpose
How does Levomilnacipran work?
Levomilnacipran works by affecting neurotransmitters in the brain, specifically serotonin and norepinephrine. These chemicals help regulate mood and emotional balance. Levomilnacipran belongs to a class of medications called serotonin-norepinephrine reuptake inhibitors, which increase the levels of these neurotransmitters in the brain. Think of it like adjusting the volume on a radio to improve the sound quality. By increasing serotonin and norepinephrine, Levomilnacipran helps improve mood and reduce symptoms of depression.
Is Levomilnacipran effective?
Yes, Levomilnacipran is effective for treating major depressive disorder, which is a condition characterized by persistent sadness and loss of interest in activities. Clinical studies show that Levomilnacipran significantly improves symptoms of depression compared to a placebo. It works by affecting neurotransmitters in the brain, which helps improve mood and emotional balance. If you have concerns about the effectiveness of Levomilnacipran, discuss them with your doctor. They can help determine if this medication is right for you.
What is Levomilnacipran?
Levomilnacipran is a medication used to treat major depressive disorder, which is a condition characterized by persistent sadness and loss of interest in activities. It belongs to a class of drugs called serotonin-norepinephrine reuptake inhibitors, which work by affecting neurotransmitters in the brain to improve mood and emotional balance. Levomilnacipran is primarily used for depression but may also be prescribed for other conditions as determined by your doctor. Always follow your doctor's instructions when taking Levomilnacipran.
Directions for Use
For how long do I take Levomilnacipran?
Levomilnacipran is usually taken long-term for managing chronic conditions like major depressive disorder. The duration of use depends on your response to the medication and any side effects you experience. Always follow your doctor's instructions regarding how long to take Levomilnacipran. Do not stop taking it without medical advice, as this could worsen your condition. Your doctor will help determine the appropriate duration of treatment based on your health needs.
How do I dispose of Levomilnacipran?
To dispose of Levomilnacipran, take it to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of it properly to prevent harm to people or the environment. If you can't find a take-back program, you can throw it in the trash at home. First, mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and then throw it away. Always keep medications out of reach of children and pets.
How do I take Levomilnacipran?
Take Levomilnacipran once daily, preferably in the morning, with or without food. Swallow the capsule whole; do not crush or chew it. If you miss a dose, take it as soon as you remember unless it's close to your next dose. In that case, skip the missed dose and continue your regular schedule. Do not take two doses at once. Avoid alcohol while on this medication, as it can increase side effects. Always follow your doctor's specific instructions regarding diet and fluid intake while taking Levomilnacipran.
How long does it take for Levomilnacipran to start working?
Levomilnacipran may start working within a few weeks, but it can take several weeks to achieve its full therapeutic effect. Individual factors like age, overall health, and the severity of depression can affect how quickly you notice improvements. It's important to take Levomilnacipran exactly as prescribed and continue regular check-ups with your doctor. They can help monitor your progress and make any necessary adjustments to your treatment plan. Always communicate with your doctor about how you're feeling while taking Levomilnacipran.
How should I store Levomilnacipran?
Store Levomilnacipran at room temperature, away from moisture and light. Keep it in a tightly closed container to protect it from damage. Do not store it in humid places like bathrooms, as moisture can affect its effectiveness. Always keep Levomilnacipran out of reach of children and pets to prevent accidental ingestion. Check the expiration date regularly and properly dispose of any unused or expired medication.
What is the usual dose of Levomilnacipran?
The usual starting dose of Levomilnacipran for adults is 20 mg once daily. Your doctor may increase the dose to 40 mg daily based on your response and tolerance. The maximum recommended dose is 120 mg per day. Dose adjustments may be necessary for elderly patients or those with kidney problems. Always follow your doctor's specific dosing instructions for your health needs. Do not adjust your dose without consulting your healthcare provider.
Warnings and Precautions
Can I take Levomilnacipran with other prescription drugs?
Levomilnacipran can interact with other medications, increasing the risk of adverse effects. For example, combining it with other antidepressants or blood thinners can increase the risk of bleeding. It may also interact with medications that affect heart rhythm. Always inform your doctor about all medications you take to prevent interactions. They can help ensure your treatment remains safe and effective by monitoring for potential drug interactions.
Can Levomilnacipran be taken safely while breastfeeding?
The safety of Levomilnacipran while breastfeeding is not well-established. It's unclear if this medication passes into human breast milk. Animal studies suggest it may appear in milk, raising concerns about potential effects on a nursing infant. If you're breastfeeding or planning to breastfeed, talk with your doctor about safer medication options. They can help you make informed decisions about your treatment while ensuring the safety of your baby. Always discuss any concerns with your healthcare provider.
Can Levomilnacipran be taken safely while pregnant?
The safety of Levomilnacipran during pregnancy is not well-established. Limited evidence makes it difficult to provide definitive advice. Animal studies suggest potential risks, but human data is lacking. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby. Always discuss any concerns about medication use during pregnancy with your healthcare provider.
Does Levomilnacipran have adverse effects?
Yes, Levomilnacipran can have adverse effects, which are unwanted reactions to a medication. Common adverse effects include nausea, headache, and increased sweating. These occur in less than 10% of users. Serious side effects, though rare, include increased blood pressure and risk of bleeding. If you notice any new or worsening symptoms, contact your doctor. They can help determine if these symptoms are related to Levomilnacipran and suggest appropriate actions to manage them.
Does Levomilnacipran have any safety warnings?
Yes, Levomilnacipran has important safety warnings. It can increase blood pressure, so regular monitoring is necessary. It may also increase the risk of bleeding, especially if taken with blood thinners. Not adhering to these warnings can lead to serious health issues like hypertension or bleeding complications. If you experience symptoms like severe headache, chest pain, or unusual bleeding, seek medical help immediately. Always discuss any concerns with your doctor to ensure safe use of Levomilnacipran.
Is it safe to drink alcohol while taking Levomilnacipran?
It's best to avoid alcohol while taking Levomilnacipran. Alcohol can increase the risk of side effects like dizziness or drowsiness. It may also worsen symptoms of depression. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like increased dizziness or mood changes. Talk with your doctor about alcohol use while taking Levomilnacipran to get personalized advice based on your specific health situation.
Is it safe to exercise while taking Levomilnacipran?
Yes, you can exercise while taking Levomilnacipran. However, be aware that this medication can cause dizziness or increased heart rate, which might affect your exercise capacity. Start with light to moderate activities and monitor how your body responds. If you feel dizzy or unusually fatigued, slow down or stop exercising and rest. Always talk with your doctor about your exercise routine while taking Levomilnacipran, especially if you have concerns about your specific situation.
Is it safe to stop Levomilnacipran?
It's not safe to stop Levomilnacipran suddenly. This medication is usually used long-term for chronic conditions like depression. Stopping it abruptly can cause withdrawal symptoms such as dizziness, irritability, or mood changes. Always talk with your doctor before stopping Levomilnacipran. They may suggest gradually reducing your dose to minimize withdrawal effects. Your doctor will help you make any medication changes safely to protect your health.
Is Levomilnacipran addictive?
Levomilnacipran is not considered addictive or habit-forming. It does not cause dependency or withdrawal symptoms when you stop taking it. Levomilnacipran works by affecting neurotransmitters in the brain, but it does not alter brain chemistry in a way that leads to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed. If you have concerns about medication dependence, discuss them with your doctor for reassurance and guidance.
Is Levomilnacipran safe for the elderly?
Elderly individuals may be more vulnerable to the side effects of Levomilnacipran, such as increased blood pressure or dizziness. These risks require careful monitoring. Levomilnacipran can be used safely in the elderly with appropriate dose adjustments and regular check-ups. Always consult your doctor about the risks and benefits of using Levomilnacipran if you are elderly. They can help ensure safe and effective treatment tailored to your health needs.
What are the most common side effects of Levomilnacipran?
Common side effects of Levomilnacipran include nausea, headache, and increased sweating. These side effects are unwanted reactions that can occur when taking a medication. They affect less than 10% of users. If you experience new symptoms after starting Levomilnacipran, they might be temporary or unrelated to the medication. It's important to talk with your doctor before stopping any medication. They can help determine if the side effects are related to Levomilnacipran and suggest ways to manage them.
Who should avoid taking Levomilnacipran?
Levomilnacipran should not be used if you have uncontrolled narrow-angle glaucoma, which is a condition where fluid pressure in the eye increases. It's also contraindicated if you're allergic to it or its ingredients. Caution is needed if you have high blood pressure or heart problems, as Levomilnacipran can increase blood pressure. Always consult your doctor about these concerns to ensure safe use of Levomilnacipran.