Levomilnacipran
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Drug Status
Government Approvals
US(FDA)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Serotonin and Norepinephrine Reuptake Inhibitor
Controlled Drug Substance
NO
Levomilnacipran
Summary
Levomilnacipran is used to treat major depressive disorder in adults. It helps improve mood and maintain mental balance.
Levomilnacipran works by increasing the levels of two neurotransmitters, serotonin and norepinephrine, in the brain. This helps improve mood and alleviate symptoms of depression.
The usual daily dose for adults ranges from 40 mg to 120 mg, taken once daily. It can be taken with or without food. It is not recommended for use in children under 18 years of age.
Common side effects include nausea, constipation, excessive sweating, sexual problems, and insomnia. Serious effects can include suicidal thoughts, serotonin syndrome, and high blood pressure.
Levomilnacipran can increase the risk of suicidal thoughts, especially in young adults. It can interact with other medications, like MAOIs, which can lead to serotonin syndrome. It's also contraindicated in patients with hypersensitivity to the drug. Always consult your doctor before starting or stopping this medication.
Indications and Purpose
How does Levomilnacipran work?
Levomilnacipran acts by inhibiting the reuptake of serotonin and norepinephrine, two neurotransmitters in the brain, which helps improve mood and alleviate symptoms of depression.
How does one know if Levomilnacipran is working?
The benefit of Levomilnacipran is evaluated through regular follow-up visits with your healthcare provider, who will monitor your symptoms and any side effects to adjust treatment as necessary.
Is Levomilnacipran effective?
Levomilnacipran has been shown to be effective in treating major depressive disorder in adults through clinical trials, demonstrating improvement in depressive symptoms compared to placebo.
What is Levomilnacipran?
Levomilnacipran is used to treat major depressive disorder in adults. It works by increasing the levels of serotonin and norepinephrine in the brain, which helps maintain mental balance and improve mood.
What is Levomilnacipran used for?
Levomilnacipran is indicated for the treatment of major depressive disorder in adults, helping to alleviate symptoms of depression by balancing neurotransmitters in the brain.
Directions for Use
For how long do I take Levomilnacipran?
Levomilnacipran is typically used for several weeks or longer, depending on the individual's response and the doctor's recommendation. It is important to continue taking it even if you feel well, and not to stop without consulting your doctor.
How do I take Levomilnacipran?
Levomilnacipran should be taken once daily, with or without food, at the same time each day. There are no specific food restrictions, but avoid alcohol as it can increase side effects.
How long does it take for Levomilnacipran to start working?
Levomilnacipran may take several weeks or longer to show its full benefits. It's important to continue taking it as prescribed and consult your doctor if you have concerns about its effectiveness.
How should I store Levomilnacipran?
Store Levomilnacipran at room temperature, away from light, excess heat, and moisture. Keep it in its original container, tightly closed, and out of reach of children.
What is the usual dose of Levomilnacipran?
For adults, the usual daily dose of Levomilnacipran ranges from 40 mg to 120 mg, taken once daily. It is not recommended for use in children under 18 years of age.
Warnings and Precautions
Can I take Levomilnacipran with other prescription drugs?
Significant interactions include MAOIs, other serotonergic drugs, and medications affecting blood clotting like NSAIDs and warfarin. These can increase the risk of serotonin syndrome and bleeding.
Can I take Levomilnacipran with vitamins or supplements?
Levomilnacipran may interact with supplements like St. John's Wort and tryptophan, increasing the risk of serotonin syndrome. Always consult your doctor before starting any new supplements.
Can Levomilnacipran be taken safely while breastfeeding?
While it's unclear if Levomilnacipran passes into breast milk, caution is advised. Monitor infants for sedation, irritability, or poor feeding, and consult your doctor for guidance on breastfeeding while on this medication.
Can Levomilnacipran be taken safely while pregnant?
Levomilnacipran may pose risks during pregnancy, such as postpartum hemorrhage and neonatal complications. There is a pregnancy registry to monitor outcomes, but specific evidence of fetal harm is not detailed.
Is it safe to drink alcohol while taking Levomilnacipran?
Drinking alcohol while taking Levomilnacipran is not recommended as it may increase the risk of side effects and can affect the release of the medication, potentially leading to increased side effects.
Is it safe to exercise while taking Levomilnacipran?
Levomilnacipran may cause dizziness or drowsiness, which could affect your ability to exercise safely. It's important to understand how the medication affects you before engaging in physical activities.
Is Levomilnacipran safe for the elderly?
Elderly patients may be at greater risk for side effects like hyponatremia. It's important for them to be closely monitored by their healthcare provider, especially if they have other health conditions or are taking multiple medications.
Who should avoid taking Levomilnacipran?
Important warnings include the risk of suicidal thoughts, especially in young adults, serotonin syndrome, high blood pressure, and interactions with MAOIs. It's contraindicated in patients with hypersensitivity to the drug or those taking MAOIs.
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