Fexofenadine
Perennial Allergic Rhinitis, Urticaria
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
Histamine-1 Receptor Antagonist
Controlled Drug Substance
NO
Fexofenadine
Summary
Fexofenadine is used to relieve allergy symptoms associated with seasonal allergic rhinitis like runny nose, sneezing and itchy eyes. It is also used to treat chronic urticaria, which includes symptoms like hives and itching.
Fexofenadine works by blocking the effects of histamine, a substance in the body that causes allergy symptoms. By preventing histamine from binding to its receptors, it reduces symptoms like sneezing, runny nose and itchy eyes.
For adults and children 12 years and older, the usual dose is 180 mg once daily or 60 mg twice daily. For children aged 2 to under 12 years, the dose is 5 mL of the suspension every 12 hours. Always follow your doctor's advice for the correct dosage.
Common side effects of Fexofenadine include headache, dizziness, diarrhea, and fatigue. Serious side effects, though rare, include difficulty breathing, swelling and severe allergic reactions.
Do not use Fexofenadine if you have had an allergic reaction to it or its ingredients. Consult a doctor if you have kidney disease, are pregnant or breastfeeding. Avoid taking it with fruit juices or antacids containing aluminum or magnesium.
Indications and Purpose
How does Fexofenadine work?
Fexofenadine works by blocking the effects of histamine, a substance in the body that causes allergy symptoms. By preventing histamine from binding to its receptors, it reduces symptoms like sneezing, runny nose, and itchy eyes.
Is Fexofenadine effective?
Fexofenadine is an effective antihistamine that relieves allergy symptoms by blocking histamine, a substance in the body that causes allergic reactions. Clinical studies have shown it to be effective in reducing symptoms like runny nose, sneezing, and itchy eyes.
What is Fexofenadine?
Fexofenadine is an antihistamine used to relieve allergy symptoms like runny nose, sneezing, and itchy eyes. It works by blocking histamine, a substance in the body that causes allergic reactions. It is effective for both seasonal allergic rhinitis and chronic urticaria.
Directions for Use
For how long do I take Fexofenadine?
Fexofenadine is typically used as long as allergy symptoms persist. It is important to continue taking it even if you feel well, as it controls symptoms but does not cure the condition. Always follow your doctor's guidance on the duration of use.
How do I dispose of Fexofenadine?
If you can, bring unused medicines to a drug take-back program or collection site at a pharmacy or hospital. They will dispose of this medicine properly so they don't harm people or the environment. If you can't find a take-back program, you can throw most medicines in the trash at home. But first, take them out of their original containers, mix them with something undesirable like used coffee grounds, seal the mixture in a plastic bag and throw it away.
How do I take Fexofenadine?
Take Fexofenadine with water, and avoid taking it with fruit juices like orange, grapefruit, or apple juice, as they can reduce its effectiveness. It can be taken with or without food, but follow your doctor's instructions for best results.
How long does it take for Fexofenadine to start working?
Fexofenadine typically starts working within one hour of taking it. It reaches its maximum effect in about 6 hours and provides relief for up to 24 hours.
How should I store Fexofenadine?
Store Fexofenadine in its original container, tightly closed, at room temperature, away from excess heat and moisture. Keep it out of reach of children and do not store it in the bathroom.
What is the usual dose of Fexofenadine?
For adults and children 12 years and older, the usual dose is 180 mg once daily or 60 mg twice daily. For children aged 2 to under 12 years, the dose is 5 mL of the suspension every 12 hours. Always follow your doctor's advice for the correct dosage.
Warnings and Precautions
Can Fexofenadine be taken safely while breastfeeding?
Fexofenadine is not recommended for breastfeeding mothers, as it may pass into breast milk. Consult your doctor for alternative treatments if you are breastfeeding.
Can Fexofenadine be taken safely while pregnant?
There is limited data on the use of Fexofenadine during pregnancy. It should only be used if clearly necessary and prescribed by a doctor. Consult your healthcare provider for personalized advice.
Can I take Fexofenadine with other prescription drugs?
Fexofenadine should not be taken with antacids containing aluminum or magnesium, as they can reduce its effectiveness. Consult your doctor about any other medications you are taking to avoid potential interactions.
Does Fexofenadine have adverse effects?
Adverse effects are unwanted or harmful effects caused by a medicine. Fexofenadine may cause adverse effects like headache, dizziness, nausea, or drowsiness, which are not very common. Serious adverse effects are rare but can include allergic reactions like rash, itching, or swelling, and require immediate medical attention. It's important to report any new symptoms to a healthcare provider and consult them before stopping the medicine.
Does Fexofenadine have any safety warnings?
Fexofenadine has some safety warnings. Avoid taking it with fruit juices like apple, orange, or grapefruit, as they can reduce its effectiveness. Be cautious if you have kidney problems, as the drug is processed by the kidneys. Watch for signs of an allergic reaction, such as rash, itching, or swelling, and seek medical help if these occur. Always inform your doctor about other medications you're taking to avoid interactions.
Is Fexofenadine addictive?
Fexofenadine has no known potential for dependence or addiction. It is considered safe to use without the risk of becoming habit-forming. You can take it as prescribed by your doctor without worrying about addiction.
Is Fexofenadine safe for the elderly?
Elderly patients should consult their doctor before using Fexofenadine, as they may require a different dosage. There is limited data on its use in this age group, so caution is advised.
Is it safe to drink alcohol while taking Fexofenadine?
Most people tolerate Fexofenadine well, and occasional alcoholic drinks should not affect the way this medicine works. There are no well-established interactions between Fexofenadine and alcohol. However, it's always wise to consume alcohol in moderation and be aware of how your body reacts when combining alcohol with any medication.
Is it safe to exercise while taking Fexofenadine?
Fexofenadine does not typically limit the ability to exercise. It is a non-sedating antihistamine, so it should not cause drowsiness or fatigue that would affect physical activity. If you experience unusual symptoms during exercise, consult your doctor.
Is it safe to stop Fexofenadine?
Fexofenadine is typically used for symptomatic relief of allergies, which means it can be stopped without serious risks. However, stopping it may result in the return of allergy symptoms like sneezing, itching, or runny nose. There are no known withdrawal or rebound symptoms associated with stopping Fexofenadine. It's always best to consult with a doctor before stopping any medication to ensure it's safe and appropriate for your situation.
What are the most common side effects of Fexofenadine?
A side effect is an unwanted effect caused by a medicine. Common side effects of Fexofenadine include headache, dizziness, nausea, and drowsiness. These are not very common and may not happen to everyone. Sometimes, new symptoms can occur when starting a new medicine, but they might not be related to the medicine itself. Always talk to a healthcare provider before stopping any medicine.
Who should avoid taking Fexofenadine?
Do not use Fexofenadine if you have had an allergic reaction to it or its ingredients. Consult a doctor if you have kidney disease, are pregnant, or breastfeeding. Avoid taking it with fruit juices or antacids containing aluminum or magnesium.
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