Colestipol
Pseudomembranous Enterocolitis, Diarrhea ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
No
Pharmaceutical Class
Bile Acid Sequestrant
Controlled Drug Substance
No
colestipol
Summary
Colestipol is used to lower high cholesterol levels, which is a condition where there is too much cholesterol in the blood. It helps reduce LDL cholesterol, which is the "bad" cholesterol, lowering the risk of heart disease.
Colestipol works by binding bile acids in the intestine, which are substances needed to digest fats. This process prevents bile acids from being reabsorbed, causing the liver to use more cholesterol to make new bile acids, thus reducing cholesterol levels in the blood.
The usual starting dose of Colestipol for adults is 5 grams once or twice daily. It is taken orally, usually with meals to improve absorption. The maximum recommended dose is 30 grams per day. Always follow your doctor's specific dosing instructions.
Common side effects of Colestipol include constipation, bloating, and gas, which are usually mild. These effects can often be managed by taking the medication with meals and increasing dietary fiber. Severe or persistent stomach issues should be discussed with a doctor.
Colestipol can interfere with the absorption of certain medications and vitamins. It is not suitable for people with complete biliary obstruction, which is a blockage in the bile duct. Always inform your doctor about all medications and supplements you are taking to avoid interactions.
Indications and Purpose
How does Colestipol work?
Colestipol works by binding bile acids in the intestine, which are substances needed to digest fats. This binding process prevents the reabsorption of bile acids, causing the liver to use more cholesterol to make new bile acids. This reduces the level of cholesterol in the blood. Think of it like a sponge soaking up excess bile acids, helping to lower cholesterol levels.
Is Colestipol effective?
Colestipol is effective in lowering cholesterol levels. It works by binding bile acids in the intestine, which helps reduce cholesterol in the blood. Clinical studies show it can significantly lower LDL cholesterol, which is the "bad" cholesterol. This helps reduce the risk of heart disease.
What is Colestipol?
Colestipol is a medication used to lower cholesterol levels. It belongs to a class of drugs called bile acid sequestrants. It works by binding bile acids in the intestine, which helps reduce cholesterol in the blood. Colestipol is primarily used to treat high cholesterol and may be used alone or with other cholesterol-lowering medications.
Directions for Use
For how long do I take Colestipol?
Colestipol is usually a long-term medication for managing cholesterol levels. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Colestipol treatment.
How do I dispose of Colestipol?
Dispose of unused Colestipol by taking it to a drug take-back program or collection site at a pharmacy or hospital. If you can't find a take-back program, you can throw it in the trash at home. Mix it with something undesirable like used coffee grounds, seal it in a plastic bag, and throw it away.
How do I take Colestipol?
Take Colestipol as directed by your doctor. It's usually taken once or twice daily. You should take it with meals to improve absorption. Do not crush or chew the tablets. If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose. Avoid taking two doses at once. Follow any dietary or beverage restrictions your doctor advises.
How long does it take for Colestipol to start working?
Colestipol begins working in your body shortly after you take it, but it may take several weeks to see significant changes in your cholesterol levels. The full therapeutic effect can take up to a month or more. Individual factors like diet, exercise, and overall health can affect how quickly you see results. Take it exactly as prescribed for the best results.
How should I store Colestipol?
Store Colestipol at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms. Always keep it out of reach of children to prevent accidental ingestion. Check the expiration date regularly and dispose of any unused or expired medication properly.
What is the usual dose of Colestipol?
The usual starting dose of Colestipol for adults is 5 grams once or twice daily. Your doctor may adjust the dose based on your response and needs. The maximum recommended dose is 30 grams per day. Always follow your doctor's specific dosing instructions. Dose adjustments may be needed for special populations like the elderly.
Warnings and Precautions
Can Colestipol be taken safely while breastfeeding?
Colestipol is considered safe while breastfeeding because it is not absorbed into the bloodstream and therefore unlikely to pass into breast milk. However, always consult your doctor before taking any medication while breastfeeding to ensure it is safe for you and your baby.
Can Colestipol be taken safely while pregnant?
Colestipol is generally considered safe during pregnancy, as it is not absorbed into the bloodstream. However, always consult your doctor before taking any medication during pregnancy. Your doctor can help create a treatment plan that protects both you and your baby.
Can I take Colestipol with other prescription drugs?
Colestipol can interact with other medications by reducing their absorption. This includes certain blood thinners, thyroid medications, and antibiotics. To prevent interactions, take other medications at least 1 hour before or 4 hours after Colestipol. Always inform your doctor about all medications you are taking.
Does Colestipol have adverse effects?
Adverse effects are unwanted reactions to a medication. Common adverse effects of Colestipol include constipation, bloating, and gas. These effects are usually mild. Serious adverse effects are rare but can include severe constipation or intestinal blockage. If you experience any new or worsening symptoms, contact your doctor.
Does Colestipol have any safety warnings?
Colestipol has important safety warnings. It can interfere with the absorption of certain medications and vitamins. Not adhering to these warnings can lead to nutrient deficiencies or reduced effectiveness of other medications. Always follow your doctor's instructions and inform them of all medications and supplements you are taking.
Is Colestipol addictive?
Colestipol is not addictive or habit-forming. It doesn't cause dependency or withdrawal symptoms when you stop taking it. This medication works by binding bile acids in the intestine, which doesn't affect brain chemistry in ways that could lead to addiction. You won't experience cravings for this medication or feel compelled to take more than prescribed.
Is Colestipol safe for the elderly?
Colestipol is generally safe for the elderly, but they may be more vulnerable to side effects like constipation. It's important for older adults to stay hydrated and maintain a fiber-rich diet. Regular monitoring by a healthcare provider is recommended to ensure safe and effective treatment.
Is it safe to drink alcohol while taking Colestipol?
It's best to limit alcohol while taking Colestipol. Alcohol can increase the risk of liver problems and may worsen side effects like constipation. If you choose to drink, do so in moderation and talk with your doctor about alcohol use while taking Colestipol to get personalized advice.
Is it safe to exercise while taking Colestipol?
You can exercise while taking Colestipol. However, this medication can cause constipation, which might make you feel uncomfortable during physical activity. To exercise safely, drink plenty of water and eat a fiber-rich diet. If you experience any discomfort, talk with your doctor.
Is it safe to stop Colestipol?
Colestipol is often used long-term for managing cholesterol levels. Stopping it suddenly may cause your cholesterol levels to rise. Always talk with your doctor before stopping Colestipol. They might suggest gradually reducing your dose or switching to a different medication to keep your condition under control.
What are the most common side effects of Colestipol?
Side effects are unwanted reactions that can happen when taking a medication. Common side effects of Colestipol include constipation, bloating, and gas. These effects vary from person to person. If you notice new symptoms after starting Colestipol, they might be temporary or unrelated to the medication. Talk with your doctor before stopping any medication.
Who should avoid taking Colestipol?
Don't take Colestipol if you're allergic to it or its ingredients. It's not suitable for people with complete biliary obstruction, which is a blockage in the bile duct. Use caution if you have a history of constipation or intestinal blockage. Always consult your doctor about these concerns.
