Atropine
Drug Status
Government Approvals
UK(BNF)
WHO Essential Medicine
NO
Known Teratogen
NO
Pharmaceutical Class
None
Controlled Drug Substance
NO

Atropine
Summary
Atropine is used to treat conditions like bradycardia, which is a slow heart rate. It is also used to reduce saliva production during surgeries and to dilate pupils for eye examinations. Furthermore, it can be used as an antidote for certain types of poisoning.
Atropine works by blocking the action of a neurotransmitter called acetylcholine. This helps to relax smooth muscles, reduce bodily secretions, and increase heart rate.
The dosage of Atropine varies based on the condition being treated and the patient's age and weight. For adults, the typical dose can range from 0.4 mg to 1 mg as needed. For children, the dose is usually calculated based on body weight, typically around 0.01 mg/kg.
Common side effects of Atropine include dry mouth, blurred vision, sensitivity to light, and constipation. Serious adverse effects can include difficulty urinating, confusion, and rapid heartbeat.
Atropine should not be used by individuals with certain conditions such as glaucoma, myasthenia gravis, or obstructive gastrointestinal disorders. It can cause side effects like drowsiness or dizziness which may impair your ability to drive or operate heavy machinery. If you experience these side effects, avoid such activities and consult your doctor.
Indications and Purpose
How does Atropine work?
Atropine works by blocking the action of acetylcholine, a neurotransmitter that affects various bodily functions. By inhibiting acetylcholine, Atropine helps to relax smooth muscles, reduce bodily secretions, and increase heart rate. This makes it useful for treating conditions like bradycardia and reducing saliva production during surgery.
Is Atropine effective?
Atropine is a well-established medication used to treat various conditions, such as bradycardia (slow heart rate) and to reduce saliva production during surgery. Its effectiveness is supported by clinical studies and long-term use in medical practice. Always consult your healthcare provider for more information on its effectiveness for your specific condition.
What is Atropine?
Atropine is a medication used to treat conditions like bradycardia (slow heart rate) and to reduce saliva production during surgery. It works by blocking certain receptors in the body, which helps to relax muscles and reduce secretions. Atropine is also used in eye drops to dilate pupils for eye examinations.
Directions for Use
For how long do I take Atropine?
The duration of Atropine use depends on the condition being treated. It can be used as a single dose for acute situations or over a longer period for chronic conditions. Always follow your healthcare provider's guidance on how long to use Atropine.
How do I take Atropine?
Atropine can be taken with or without food, depending on the form prescribed. Follow your healthcare provider's instructions on how to take it. There are no specific food restrictions, but it is important to maintain a balanced diet and stay hydrated while using Atropine.
How long does it take for Atropine to start working?
Atropine typically starts working within minutes when administered intravenously, making it effective for acute situations like bradycardia. The onset of action may vary depending on the form and route of administration. Always follow your healthcare provider's guidance for your specific condition.
How should I store Atropine?
Atropine should be stored at room temperature, away from light and moisture. Keep it out of reach of children and pets. Do not store it in the bathroom, and ensure the container is tightly closed when not in use. Follow any additional storage instructions provided by your pharmacist or healthcare provider.
What is the usual dose of Atropine?
The dosage of Atropine varies based on the condition being treated, age, and weight of the patient. For adults, the typical dose can range from 0.4 mg to 1 mg, administered as needed. For children, the dose is usually calculated based on body weight, typically around 0.01 mg/kg. Always follow your doctor's specific instructions for dosing.
Warnings and Precautions
Can Atropine be taken safely while breastfeeding?
Atropine may pass into breast milk and could affect a nursing infant. It is important to consult your healthcare provider before using Atropine while breastfeeding to weigh the potential risks and benefits.
Can Atropine be taken safely while pregnant?
Atropine should be used during pregnancy only if clearly needed, as there is limited data on its safety. It is important to discuss the potential risks and benefits with your healthcare provider before using Atropine while pregnant.
Can I take Atropine with other prescription drugs?
Atropine can interact with other medications, such as antihistamines, antidepressants, and certain antipsychotics, which may increase the risk of side effects. It is important to inform your healthcare provider of all medications you are taking to avoid potential interactions.
Is Atropine safe for the elderly?
Elderly patients may be more sensitive to the effects of Atropine, particularly its side effects like confusion or dizziness. It is important for older adults to use Atropine under close medical supervision and report any unusual symptoms to their healthcare provider.
Is it safe to exercise while taking Atropine?
Atropine can cause side effects like dizziness or drowsiness, which may affect your ability to exercise safely. If you experience these symptoms, it is advisable to avoid strenuous activities and consult your doctor for guidance.
Who should avoid taking Atropine?
Atropine should not be used by individuals with certain conditions, such as glaucoma, myasthenia gravis, or obstructive gastrointestinal disorders. It is important to inform your doctor of any medical history before using Atropine. Be aware of potential side effects like dizziness or blurred vision, and avoid activities that require alertness if these occur.