Atorvastatin
Coronary Artery Disease, Hypercholesterolemia ... show more
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Drug Status
Government Approvals
US(FDA), UK(BNF)
WHO Essential Medicine
YES
Known Teratogen
NO
Pharmaceutical Class
HMG-CoA Reductase Inhibitor
Controlled Drug Substance
NO
Atorvastatin
Learn more about this medicine -
Click HereSummary
Atorvastatin is used to lower high cholesterol levels, raise good cholesterol, lower triglyceride levels, and reduce the risk of heart attacks, strokes, and other heart-related issues.
Atorvastatin works by blocking an enzyme in the liver that is responsible for making cholesterol. By reducing cholesterol production, it helps lower total cholesterol levels in the blood.
Atorvastatin is typically taken once a day, either before or after you eat. If taken before eating, wait at least 1 hour after taking it. If taken after eating, wait at least 2 hours after taking it.
Common side effects of Atorvastatin include stuffy nose, sore throat, diarrhea, urinary tract infection, upset stomach, nausea, muscle cramps, joint pain, trouble sleeping, and in serious cases, muscle damage and liver problems.
Atorvastatin is not recommended for pregnant or breastfeeding women. It can interact with several medications, so always inform your doctor about all the medications you're taking to avoid dangerous interactions. If you experience significant mood changes, muscle pain, or discomfort, contact your doctor immediately.
Indications and Purpose
What is Atorvastatin used for?
Atorvastatin is used to lower high cholesterol and reduce the risk of heart disease. It helps decrease LDL cholesterol and triglycerides while increasing HDL cholesterol. It is often used alongside diet, exercise, and other lifestyle changes.
How does Atorvastatin work?
Atorvastatin works by blocking an enzyme in the liver that is responsible for making cholesterol. This action reduces the amount of cholesterol in the blood, helping to lower LDL cholesterol levels and reduce the risk of heart disease.
Is Atorvastatin effective?
Atorvastatin is primarily used to lower cholesterol levels and reduce the risk of heart disease. It works by blocking an enzyme in the liver responsible for making cholesterol. Clinical trials have shown that Atorvastatin effectively lowers LDL cholesterol and reduces the risk of heart attacks and strokes.
How does one know if Atorvastatin is working?
Atorvastatin is used to lower cholesterol levels. Its effectiveness is monitored through regular blood tests to check cholesterol levels. A decrease in LDL cholesterol and total cholesterol indicates the medicine is working. Follow your healthcare provider's instructions for regular testing.
Directions for Use
What is the usual dose of Atorvastatin?
The usual starting dose of Atorvastatin for adults is 10 mg once daily. The dose may be adjusted based on individual response and cholesterol levels, with a maximum recommended dose of 80 mg per day. For children or the elderly, dosing may differ, and it's crucial to follow a healthcare provider's instructions for dosing.
How do I take Atorvastatin?
Take Atorvastatin once daily, with or without food. It's best to take it at the same time each day. Avoid grapefruit juice, as it can interact with the medication. Follow your healthcare provider's instructions for dosage and dietary recommendations.
For how long do I take Atorvastatin?
Atorvastatin is used for long-term management of high cholesterol and related conditions. The duration of use depends on individual health needs and response to treatment. It's important to follow your healthcare provider's instructions regarding how long to take this medication.
How long does it take for Atorvastatin to start working?
Atorvastatin begins to work within 2 weeks, but it may take up to 4 weeks to see the full effect on cholesterol levels. Individual factors like diet and lifestyle can affect how quickly it works. Follow your healthcare provider's instructions for best results.
How should I store Atorvastatin?
Store Atorvastatin at room temperature, away from moisture and light. Keep it in a secure place out of reach of children. Avoid storing it in the bathroom or near a sink to prevent exposure to moisture.
Warnings and Precautions
Who should avoid taking Atorvastatin?
Atorvastatin should not be used in individuals with active liver disease or unexplained persistent elevations in liver enzymes. It is also contraindicated in pregnant or breastfeeding women due to potential harm to the baby. People with known allergies to Atorvastatin should avoid it. Always inform your healthcare provider about your medical history before starting this medication.
Can I take Atorvastatin with other prescription drugs?
Atorvastatin can interact with certain medications, increasing the risk of side effects. Notable interactions include drugs like cyclosporine, certain antibiotics, and antifungals, which can increase Atorvastatin levels in the blood. This can lead to muscle problems. Always inform your healthcare provider about all medications you are taking to avoid potential interactions.
Can I take Atorvastatin with vitamins or supplements?
Confirmed interactions with Atorvastatin include grapefruit juice, which can increase the medicine's levels in the blood, potentially leading to side effects. There is no confirmed need for supplementation due to nutrient depletion by Atorvastatin. Always inform your healthcare provider about all medications and supplements you are taking to avoid potential interactions.
Can Atorvastatin be taken safely while pregnant?
Atorvastatin is not safe to use during pregnancy and is contraindicated. It can harm the developing fetus, particularly affecting fetal development. Women who are pregnant or planning to become pregnant should avoid this medication and consult their healthcare provider for alternatives.
Can Atorvastatin be taken safely while breastfeeding?
Atorvastatin is not recommended while breastfeeding, as it is unknown if it is excreted into breast milk and could potentially affect the infant. Consult a healthcare provider for advice on alternative treatments while breastfeeding.
Is Atorvastatin safe for the elderly?
Elderly patients may be more sensitive to the effects of Atorvastatin, particularly muscle-related side effects. It's important for older adults to have regular monitoring of liver function and muscle health while taking this medication. Always follow a healthcare provider's guidance.
Is it safe to exercise while taking Atorvastatin?
Most people tolerate Atorvastatin well, and it should not limit your ability to exercise. However, if you experience muscle pain or weakness during physical activity, consult your healthcare provider for advice.
Is it safe to drink alcohol while taking Atorvastatin?
Occasional or moderate alcohol consumption is generally considered safe while taking Atorvastatin. However, excessive alcohol can increase the risk of liver damage, as both alcohol and Atorvastatin can affect liver function. It's advisable to limit alcohol intake to avoid potential liver issues. If you experience any unusual symptoms, consult your healthcare provider for personalized advice.
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