You have the flexibility to take Trenamic E 500mg250mg Tablet at any time of day with or without food However it is recommended to take it at the same time every day Continue taking the medication for the entire duration prescribed by your doctor If you happen to miss a dose take it as soon as you remember It is important to complete the full course of treatment even if you start feeling better Do not abruptly stop taking this medication without consulting your doctor The most commonly experienced side effects of Trenamic E 500mg250mg Tablet include nausea stomach pain headache nasal congestion sinus pain sinus inflammation rash tiredness and musculoskeletal bone muscle or joint pain It may also cause diarrhea so it is advised to consume plenty of fluids to prevent dehydration If you do not observe any changes in your menstrual cycle after three consecutive periods it is recommended to consult with your doctor Before taking this medication inform your doctor if you have any kidney problems or a vaginal bleeding disorder Pregnant or breastfeeding women should seek advice from their doctor before starting Trenamic E 500mg250mg Tablet Additionally it is important to disclose all other medications you are currently taking You may be required to undergo periodic eye checkups while on this medication