Introduction to Tacrel


Tacrel, also known as Tacrolimus, is a medication primarily used to prevent organ rejection after a transplant, such as a kidney transplant. It works by suppressing the immune system to prevent it from attacking the transplanted organ.


Composition of Tacrel


Tacrel contains the active ingredient Tacrolimus, which binds to a protein in your body called FKBP12. This forms a complex that inhibits an enzyme known as calcineurin, crucial for activating T-cells. By doing this, it reduces the production of inflammatory cytokines, preventing immune system attacks on transplanted organs.


Uses of Tacrel


  • Prevention of organ rejection after a transplant
  • Suppression of the immune system to protect transplanted organs

Side Effects of Tacrel


Common Side Effects:


  • Diarrhea
  • Nausea
  • Tremors
  • Headaches
  • Dizziness
  • Changes in appetite or mood

Serious Side Effects:


  • High blood pressure
  • High blood sugar
  • Kidney issues
  • Blood clots
  • Increased risk of cancer and infections

Precautions of Tacrel


Tacrel should not be taken if you're allergic or have had a liver transplant without consulting your doctor. It's crucial to avoid grapefruit and alcohol while taking this medication. Always inform your healthcare provider about any other medications you are taking to avoid potential interactions.


How to Take Tacrel


  • Take Tacrel as an extended-release capsule every morning at the same time.
  • Ideally, take it on an empty stomach.
  • The exact dosage depends on your weight and medical condition, as determined by your doctor.

Conclusion of Tacrel


Tacrel is a vital medication for those who have undergone organ transplants, helping to prevent rejection by suppressing the immune system. While it is effective, it is important to be aware of its side effects and take necessary precautions. Always follow your doctor's instructions and report any unusual symptoms immediately.


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Written By:

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Published At: Dec 11, 2024

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Dec 11, 2024

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.