tacrel
Introduction to Tacrel
Tacrel, also known as Tacrolimus, is a medication primarily used to prevent organ rejection after a transplant, such as a kidney transplant. It works by suppressing the immune system to prevent it from attacking the transplanted organ.
Composition of Tacrel
Tacrel contains the active ingredient Tacrolimus, which binds to a protein in your body called FKBP12. This forms a complex that inhibits an enzyme known as calcineurin, crucial for activating T-cells. By doing this, it reduces the production of inflammatory cytokines, preventing immune system attacks on transplanted organs.
Uses of Tacrel
- Prevention of organ rejection after a transplant
- Suppression of the immune system to protect transplanted organs
Side Effects of Tacrel
Common Side Effects:
- Diarrhea
- Nausea
- Tremors
- Headaches
- Dizziness
- Changes in appetite or mood
Serious Side Effects:
- High blood pressure
- High blood sugar
- Kidney issues
- Blood clots
- Increased risk of cancer and infections
Precautions of Tacrel
Tacrel should not be taken if you're allergic or have had a liver transplant without consulting your doctor. It's crucial to avoid grapefruit and alcohol while taking this medication. Always inform your healthcare provider about any other medications you are taking to avoid potential interactions.
How to Take Tacrel
- Take Tacrel as an extended-release capsule every morning at the same time.
- Ideally, take it on an empty stomach.
- The exact dosage depends on your weight and medical condition, as determined by your doctor.
Conclusion of Tacrel
Tacrel is a vital medication for those who have undergone organ transplants, helping to prevent rejection by suppressing the immune system. While it is effective, it is important to be aware of its side effects and take necessary precautions. Always follow your doctor's instructions and report any unusual symptoms immediately.
Similar Medicines
Available in 2 variations

Tacrel Forte Ointment
Tacrel Forte Ointment
Tacrolimus (0.1% w/w)
tube of 10 gm Ointment

Tacrel Ointment
Tacrel Ointment
Tacrolimus (0.03% w/w)
tube of 10 gm Ointment
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