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Semi Trigem 2 Tablet SR

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Introduction to Semi Trigem 2 Tablet SR

This Medicine is commonly prescribed medications used in the management of type 2 diabetes mellitus It is a combination of three medications Glimepiride, Metformin and Pioglitazone

Each of these drugs contributes to diabetes control in different ways

Glimepiride: This belongs to the sulfonylurea class and stimulates the release of insulin from the pancreas It helps lower blood sugar levels by increasing the amount of insulin produced by the body

Metformin: This is a biguanide that improves insulin sensitivity, reducing the amount of glucose produced by the liver and enhancing the body's response to insulin It also helps lower blood sugar levels

Pioglitazone: A thiazolidinedione, it works by improving insulin sensitivity in the body's cells, allowing them to better respond to insulin This results in lower blood sugar levels

Follow the prescribed dosage provided by your healthcare provider This medication often comes in a fixeddose combination, and the number of tablets to be taken may vary

Semi Trigem 2 Tablet SR is usually taken with meals to help reduce the risk of stomach upset

Some common side effects with this medication combination The blood sugarlowering effect may lead to hypoglycemia, manifesting as shakiness, dizziness, sweating, and confusion Gastrointestinal issues such as nausea, diarrhea, or abdominal discomfort may occur Additionally, some individuals might experience fluctuations in weight

Due to the potential impact on the kidneys, those taking Metformin may undergo regular kidney function tests Similarly, periodic liver function tests may be recommended because of potential effects on the liver

If a dose is inadvertently missed, prompt action is necessary Take the missed dose as soon as you remember, unless the next scheduled dose is imminent In such cases, it's advisable to skip the missed dose to avoid doubling up

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How Semi Trigem 2 Tablet SR Works

Glimepiride, a sulfonylurea, stimulates insulin release from the pancreas, aiding in blood glucose reduction. Metformin, a biguanide, targets hepatic glucose production and enhances peripheral insulin sensitivity. Pioglitazone, a thiazolidinedione, improves insulin sensitivity in adipose tissue and skeletal muscle. Together, these medications act synergistically to regulate insulin secretion, reduce hepatic glucose output, and enhance peripheral glucose utilization. This combination offers an effective strategy for managing diabetes by addressing multiple facets of glucose homeostasis.

How to take Semi Trigem 2 Tablet SR

Follow your doctor's guidance for this medicine, taking it in the prescribed dose and duration
You can take this medicine with or without food, but maintaining a consistent time daily is recommended for better results
Swallow the drug whole; avoid chewing, crushing, or breaking it

Special Precautions about Semi Trigem 2 Tablet SR

Glimepiride increases insulin release, which can lead to hypoglycemia (low blood sugar) The risk of hypoglycemia is higher with higher doses of glimepiride Patients should be educated about recognizing the signs and symptoms of hypoglycemia and should closely monitor their blood sugar levels Dosage adjustments or changes in diet may be necessary to manage hypoglycemia
Glimepiride is primarily eliminated through the kidneys In patients with impaired renal function, the drug may accumulate, increasing the risk of hypoglycemia Regular monitoring of renal function is recommended, and dosage adjustments may be necessary in individuals with significant renal impairment
Metformin is known to cause gastrointestinal side effects, including nausea, vomiting, and diarrhea Combining it with glimepiride may increase the likelihood of these effects Informing healthcare providers about any persistent or severe gastrointestinal symptoms is important
Pioglitazone may cause fluid retention and edema Individuals should be monitored for signs of fluid retention, such as swelling, especially in those with a history of heart failure

USES IN Semi Trigem 2 Tablet SR

Type 2 diabetes mellitus

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For information purposes only. Consult a doctor before taking any medicines.

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Disease Explanation :

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Written By:

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Published At: Oct 19, 2023

Updated At: Jun 27, 2024

Reviewed By:

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Published At: Oct 19, 2023

Updated At: Jun 27, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.

Semi Trigem 2 Tablet SR

Prescription Required

Packaging :

strip of 10 tablet sr

MRP :

₹48₹53
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100% genuine medicines

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