ortholate (ERYTHROMYCIN)
What is Ortholate?
Ortholate is a type of antibiotic that works by stopping bacteria from growing. It's used to treat bacterial infections, like pneumonia or strep throat, but it doesn't work on viruses like the common cold. When you take Ortholate by mouth, it's absorbed into your body and travels to different parts of your body, including your blood and tissues. It's eventually removed from your body through your bile. However, how much Ortholate is absorbed can vary, and sometimes the right amount doesn't get into your bloodstream.
What is the usual dose of Ortholate?
**Dosage for Adults:** * For most infections: 250 mg every 6 hours or 500 mg every 12 hours. * For severe infections: Up to 4 grams per day, but no more than 1 gram twice a day. **Dosage for Children:** * For most infections: 30-50 milligrams per kilogram of body weight per day, divided into several doses. * For severe infections: Double the dose.
How do I take Ortholate?
Ortholate should be taken on an empty stomach, at least 30 minutes to 2 hours before or after meals, to optimize absorption. Swallow tablets whole with water. Avoid taking with grapefruit juice, as it may interfere with the drug.
For how long do I take Ortholate?
Treatment length for infections depends on the specific infection: * **Strep throat (streptococcal infection):** At least 10 days * **Intestinal amebiasis:** 10 to 14 days * **Urogenital infections during pregnancy:** 7 to 14 days, depending on the dose and how well you tolerate it * **Whooping cough (pertussis):** 5 to 14 days of Ortholate
What is Ortholate used for?
Ortholate is an antibiotic that treats bacterial infections. It is not effective against viral infections. Ortholate is used to treat: - Upper respiratory tract infections (e.g., bronchitis, pneumonia) - Lower respiratory tract infections (e.g., pneumonia) - Listeriosis (a bacterial infection that can cause fever, chills, and muscle aches) - Pertussis (whooping cough) - Skin and skin structure infections (e.g., cellulitis, impetigo) - Diphtheria (a bacterial infection that can cause fever, sore throat, and difficulty breathing) - Erythrasma (a bacterial infection that causes red, itchy patches on the skin) - Syphilis (a sexually transmitted infection caused by bacteria) - Intestinal amebiasis (a parasitic infection that can cause diarrhea) - Acute pelvic inflammatory disease (an infection of the female reproductive organs) Ortholate is an alternative treatment for penicillin in cases of syphilis. It is also an alternative treatment for acute pelvic inflammatory disease.
How long does it take for Ortholate to start working?
The duration of Ortholate therapy varies by condition. For streptococcal infections, treatment should last at least 10 days. Other infections may require 5–14 days or as prescribed by your doctor.
Is Ortholate effective?
Clinical evidence supports Ortholate's effectiveness in treating infections caused by susceptible bacteria. It is particularly effective for respiratory infections and skin conditions when used as directed.
How does one know if Ortholate is working?
Improvement in symptoms, such as reduced fever, pain, or infection-related discomfort, indicates effectiveness. Laboratory tests may confirm bacterial eradication in some cases.
How does Ortholate work?
Ortholate is an antibiotic that stops germs from growing by interfering with their ability to make proteins. When taken by mouth, it gets absorbed into the body but the amount absorbed can vary. It can spread to most body fluids, but levels in the spinal fluid are low unless there is an infection in the membranes surrounding the brain and spinal cord. It can cross the placenta, but levels in the baby are low. Less than 5% of the antibiotic is found in active form in urine. For best results, take Ortholate on an empty stomach.
Who should avoid taking Ortholate?
Ortholate should be used with caution in individuals with liver disease, as it can cause liver toxicity. It is contraindicated in people with a history of allergic reactions to Ortholate or other macrolide antibiotics. Patients with heart conditions, particularly those with a prolonged QT interval, should avoid Ortholate due to the risk of arrhythmias. It should also be avoided in those taking certain medications that affect heart rhythm or liver enzymes, as interactions may increase the risk of side effects.
Can I take Ortholate with vitamins or supplements?
Ortholate can interact with certain supplements, especially those containing calcium, magnesium, or aluminum, as they may reduce its absorption. Consult your doctor before taking any vitamins or supplements during treatment.
Can I take Ortholate with other prescription drugs?
Ortholate can interact with certain medications, affecting their levels or effects. * **Theophylline:** Ortholate increases theophylline levels, which can be dangerous. * **Digoxin:** Ortholate increases digoxin levels, which can cause side effects. * **Anticoagulants:** Ortholate enhances the effects of anticoagulants, especially in older adults. * **Verapamil:** Combining Ortholate and Verapamil can lead to serious side effects like low blood pressure, slow heart rate, and lactic acidosis. * **Colchicine:** Using Ortholate with Colchicine can be life-threatening.
Can Ortholate be taken safely while pregnant?
Ortholate is a type of antibiotic that is generally safe to use during pregnancy when it is clearly needed. However, there have been no adequate studies conducted in pregnant women. If Ortholate is used to treat early syphilis during pregnancy, the newborn baby should be given penicillin to prevent infection.
Can Ortholate be taken safely while breastfeeding?
Ortholate is considered safe for use during breastfeeding. It is excreted into breast milk in small amounts, but the risk to a nursing infant is generally low. However, it is important to monitor for potential side effects, such as gastrointestinal disturbances or changes in the infant's feeding behavior. It is always advisable to consult a healthcare provider before using Ortholate while breastfeeding to ensure the safety of both the mother and the baby.
Is Ortholate safe for the elderly?
Ortholate is generally safe for use in the elderly, but there are some potential side effects that should be considered. These include gastrointestinal upset, such as nausea, vomiting, and diarrhea. Ortholate can also interact with other medications, so it is important to tell your doctor about all of the medications you are taking. In some cases, Ortholate may need to be used with caution in the elderly, or the dose may need to be reduced.
How should I store Ortholate?
Store Ortholate tablets at room temperature (20°C to 25°C or 68°F to 77°F). Keep them in a dry place, away from heat, light, and moisture, and out of reach of children.
Does Ortholate make people tired or drowsy?
Ortholate does not typically cause tiredness or drowsiness. If you experience unusual fatigue, consult your doctor as it may indicate an underlying issue.
Does Ortholate cause stomach upset?
Yes, gastrointestinal side effects like nausea, vomiting, and abdominal pain are common. Taking the medication as directed can help minimize these effects. Contact your doctor if symptoms persist.
Does Ortholate affect sleep?
Sleep disturbances are not commonly reported with Ortholate. However, if you experience significant sleep issues while on the medication, consult your doctor.
Does Ortholate make it hard to think or concentrate?
Cognitive side effects like difficulty concentrating are not commonly associated with Ortholate. Inform your doctor if you notice unusual mental effects.
Does Ortholate affect mood?
Ortholate does not typically affect mood. If you experience mood changes, such as anxiety or depression, while taking the medication, seek medical advice.
Does Ortholate interfere with sexual function?
Sexual side effects are not associated with Ortholate. If you experience unexpected issues, consult your healthcare provider.
Does Ortholate affect appetite?
Ortholate may occasionally cause a loss of appetite. This effect is usually mild and temporary. If it persists, contact your doctor.
Does Ortholate cause weight gain?
Weight gain is not a known side effect of Ortholate. Any noticeable weight changes should be discussed with your doctor.
Does Ortholate cause headaches?
Headaches are not commonly reported with Ortholate. If you develop frequent or severe headaches, inform your doctor.
Does Ortholate limit driving?
Ortholate is unlikely to impair your ability to drive. However, if you experience dizziness or other side effects, avoid driving until you feel better
Is it safe to drink alcohol while taking Ortholate?
It is generally safe to drink alcohol in moderation while taking Ortholate. However, alcohol may increase the risk of certain side effects, like nausea or dizziness. Consult your doctor if you have concerns
Is it safe to drink coffee or tea while taking Ortholate?
Drinking coffee or tea while taking Ortholate is safe and does not interfere with the medication’s effectiveness. However, avoid excessive caffeine intake as it may exacerbate side effects like nervousness or upset stomach.
Is it safe to exercise while taking Ortholate?
Exercise is generally safe while taking Ortholate. If you experience side effects like dizziness or gastrointestinal discomfort, adjust your activity level accordingly. Consult your doctor for personalized advice.
What are Ortholate possible harms and risks?
Ortholate is an antibiotic that can cause side effects, mainly in the stomach and intestines. These side effects are usually mild and go away as you stop taking the medicine. However, serious side effects can occur, such as: * Liver problems * Severe diarrhea * Heart rhythm problems * Allergic reactions * Skin reactions * Kidney problems * Pancreatitis * Seizures * Hearing loss If you experience any of these serious side effects, stop taking Ortholate and contact your doctor immediately.
Available in 1 variations
Ortholate 250mg Tablet
Ortholate 250mg Tablet
Erythromycin (250mg)
strip of 10 tablets
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