--Nimesulide: Gastrointestinal disturbances, headache, dizziness, skin rash, pruritus, edema, anemia, eosinophilia, hypoglycemia, renal and hepatic damage. Paracetamol: Allergic reactions, skin rashes, blood disorders, acute pancreatitis, liver and kidney damage. Tizanidine: Dry mouth, somnolence, asthenia, dizziness, urinary tract infection, constipation, liver function abnormalities, hallucinations, nervousness, depression, rash, sweating, heartburn.