natrise

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Introduction to Natrise


Natrise is a medication used to treat low sodium levels in the blood, a condition known as hyponatremia. It is particularly beneficial for patients with heart failure or certain hormone imbalances that cause the body to retain too much water.


Composition of Natrise


The active ingredient in Natrise is Tolvaptan. This component works by blocking the action of a hormone called vasopressin in the kidneys, which helps to increase water excretion without affecting sodium levels.


Uses of Natrise


  • Treatment of low sodium levels in the blood (hyponatremia)
  • Management of fluid retention in heart failure patients
  • Correction of sodium imbalance due to hormone imbalances

Side Effects of Natrise


Common Side Effects:


  • Thirst
  • Dry mouth
  • Increased urination
  • Nausea

Serious Side Effects:


  • Liver damage
  • Dehydration
  • Low blood pressure
  • Electrolyte imbalances

Precautions of Natrise


Natrise carries a risk of liver damage, so regular monitoring of liver function is essential. It should not be used by patients with liver disease or acute kidney injury. Additionally, it is not recommended for individuals with low blood volume or those who are not producing urine. Caution is advised for people with heart or kidney disease.


How to Take Natrise


  • The usual dose for adults is 15 mg once daily.
  • The dose can be increased to a maximum of 60 mg per day.
  • Swallow the tablet whole.
  • It can be taken with or without food.

Conclusion of Natrise


Natrise is an effective medication for treating hyponatremia, especially in patients with heart failure or hormone imbalances. While it offers significant benefits, it is important to be aware of potential side effects and take necessary precautions. Always consult with a healthcare provider to ensure it is the right treatment for your condition.


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Available in 2 variations

Natrise 15gm Tablet 4s

Natrise 15gm Tablet 4s

strip of 4 tablets

Natrise 30 Tablet 4s

Natrise 30 Tablet 4s

Natrise 30 Tablet 4s

strip of 4 tablets

Related Faqs

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Can I have grapefruit juice while taking Natrise?

No, you should not take grapefruit or grapefruit juice while on Natrise. The reason being, grapefruit or grapefruit juice may increase the levels of Natrise in your blood and your sodium levels may rise too quickly.

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Does Natrise affect the sugar levels in blood?

Yes, Natrise may increase the blood sugar levels. Therefore, patients with diabetes mellitus need to be extra careful while taking Natrise and should keep a check on blood sugar levels regularly.

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What is the most important information I need to be aware of while taking Natrise?

Natrise may cause the level of sodium in your blood to increase too quickly. This quick increase in sodium levels [osmotic demyelination syndrome (ODS)] may cause serious nerve damage, which can further cause coma and even death. The symptoms of ODS could be trouble in speaking, trouble in swallowing or a feeling of food or liquid getting stuck while swallowing, drowsiness, confusion, mood changes, fits, trouble controlling body movement (involuntary movement) and weakness in muscles of the arms and legs.

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What will happen if I take excess of Natrise?

You may need urgent medical attention. Call your doctor or seek emergency service at a nearby hospital. Symptoms of taking too much Tolvaptan may include thirst, dry and flaky skin, sunken eyes, rapid heartbeat, rapid and shallow breathing, very low blood pressure, passing more urine than normal and fainting.

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Can I have grapefruit juice while taking Tolvanix?

No, you should not take grapefruit or grapefruit juice while on Tolvanix. The reason being, grapefruit or grapefruit juice may increase the levels of Tolvanix in your blood and your sodium levels may rise too quickly.

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Can I have grapefruit juice while taking Shiokem?

No, you should not take grapefruit or grapefruit juice while on Shiokem. The reason being, grapefruit or grapefruit juice may increase the levels of Shiokem in your blood and your sodium levels may rise too quickly.

Written By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.