Mefre DR 80mg/250mg Tablet

Mefre DR 80mg/250mg Tablet is a combination medication, composed of Drotaverine and Mefenamic Acid, plays a pivotal role in the treatment of various conditions characterized by muscle spasms and pain. It is specifically indicated for the following medical issues.

This medication proves effective in alleviating stomach pain associated with spasms, providing relief to individuals experiencing discomfort in the abdominal region.

For those dealing with the challenges of irritable bowel syndrome, this medication offers relief from spasms in the gastrointestinal tract.

It targets the smooth muscle spasms in the uterus, easing the discomfort associated with menstruation.

During labor, cervical spasms can occur, intensifying the pain experienced by the mother. This medication is indicated to address these spasms, contributing to a more manageable labor process.

The medication is also prescribed for the relief of chest pain associated with muscle spasms. By targeting the smooth muscles in the chest area, it helps alleviate discomfort.

In the context of gallstones, which can cause severe pain due to spasms in the gallbladder or bile ducts, It is a combination medication is utilized to mitigate the spasms and associated pain.

For individuals suffering from renal colic, characterized by spasms and pain in the kidneys, this medication proves beneficial in providing relief and improving overall comfort.

Drotaverine exerts its therapeutic effects through spasmolytic and vasodilating actions. By inhibiting the phosphodiesterase enzyme IV, it decreases cyclic AMP levels and calcium ions, leading to the dilation of unstipped muscles and blood vessels, ultimately relieving smooth muscle spasms. Mefenamic Acid, on the other hand, acts by inhibiting the synthesis and release of prostaglandins, thereby reducing inflammation and providing pain relief.

Follow the prescribed dosage and instructions provided by your healthcare professional for optimal results.

Possible side effects include hypotension, headache, tachycardia, nausea, vertigo (for Drotaverine), and nausea, vomiting, abdominal distress, and headache (for Mefenamic Acid). If any side effects persist or worsen, consult your healthcare provider.

Drotaverine is contraindicated in severe renal, hepatic, and cardiac impairment. Mefenamic Acid is contraindicated in inflammatory bowel disease and peptic ulcer.

If a dose is missed, take it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed one and continue with the regular dosing schedule. Avoid doubling the dose to make up for a missed one.