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Malart 60mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well-tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

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Available in 2 variations

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Malart 60mg Injection

Malart 60mg Injection

Artesunate (60mg)

vial of 10 ml Injection

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Malart 60mg Tablet

Malart 60mg Tablet

Artesunate (60mg)

strip of 10 tablets

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In India the availability of the product you are referring to is limited to individuals who possess a valid prescription from a doctor This means that in order to obtain this particular product one must first consult with a qualified healthcare professional who will evaluate their condition and determine if the product is suitable for their specific needs Following the consultation if the doctor deems it appropriate they will provide a prescription which allows the individual to legally obtain the product from a pharmacy or authorized medical supplier This regulation ensures that the product is used responsibly and under the guidance of a medical professional in order to prioritize the safety and wellbeing of individuals in India It is important to abide by these guidelines and seek professional advice when considering the use of any medication or healthcare product Doing so ensures that individuals receive the appropriate treatment and support for their specific health concerns

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How does Malart work?

The mechanism of action of this compound involves the generation of free radicals resulting in the eradication of the Plasmodium parasite responsible for causing malaria By producing these reactive species the compound effectively targets and destroys the parasite thereby interrupting its life cycle and preventing the continuation of the disease This unique mode of action sets it apart from other antimalarial agents as it directly attacks the parasites cellular components including proteins lipids and DNA Consequently the compound exhibits potent antimalarial activity and demonstrates effective parasite clearance Additionally its ability to induce free radicals not only contributes to the parasites demise but also helps to minimize the emergence of resistance The compounds mechanism offers a promising alternative in the fight against malarial infections as it represents a novel approach in overcoming drug resistance and ensuring the effectiveness of treatment Furthermore understanding the actions of this compound at the molecular level provides valuable insights that can be utilized to develop future antimalarial therapies with enhanced efficacy and reduced side effects

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Where does Arinatem come from?

Artemisinin a compound with potent antimalarial properties is sourced from the Artemisinin tree This tree also known as sweet wormwood or Qing Hao in traditional Chinese medicine has been used for centuries in the treatment of various ailments The extraction of artemisinin from the leaves of this tree revolutionized the field of malaria treatment offering a more effective and fasteracting solution compared to conventional drugs Artemisinins remarkable effectiveness against malaria is attributed to its unique chemical structure which allows it to target and eliminate the malaria parasites in the blood When ingested artemisinin reacts with iron from the parasites producing free radicals that damage the parasites cellular structures leading to their demise This mode of action sets artemisinin apart from other antimalarial drugs and has contributed to its widespread use in combating malaria particularly in regions where drug resistance has become a significant concern In addition to its antimalarial properties artemisinin has shown promising potential in treating various other diseases and conditions Recent studies have indicated its effectiveness against certain types of cancer including leukemia and breast cancer It has also demonstrated antiinflammatory immunosuppressive and antiviral activities Although further research is needed to harness its full therapeutic potential artemisinins versatility and unique mode of action make it a promising candidate for future drug development Overall the derivation of artemisinin from the Artemisinin tree has led to significant advancements in the treatment of malaria and holds promise for tackling other diseases Its natural origin and potent properties make it a valuable resource in the ongoing battle against global health challenges

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How does Artesar work?

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Written By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Jan 28, 2025

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.