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Larinate 60mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.

While generally well-tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.

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Available in 2 variations

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Larinate 120mg Injection

Larinate 120mg Injection

Artesunate (120mg)

vial of 15 ml Injection

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Larinate 60mg Injection

Larinate 60mg Injection

Artesunate (60mg)

vial of 5 ml Injection

Related Faqs

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Where does Larinate come from?

Artemisinin is a naturally occurring compound that is derived from the Artemisinin tree scientifically known as Artemisia annua This plant also referred to as sweet wormwood or annual wormwood is native to Asia and has been used in traditional Chinese medicine for centuries Artemisinin is extracted from the leaves and flowers of the Artemisinin tree through a process called solvent extraction Artemisinin gained worldwide attention in the 1970s when Chinese researchers discovered its potent antimalarial properties Since then it has become an essential component in the treatment of malaria particularly in cases of drugresistant strains Artemisinin has shown remarkable effectiveness in reducing the parasite load in infected individuals and has played a significant role in saving countless lives Apart from its antimalarial properties Artemisinin has also shown potential in treating other diseases such as cancer Studies have indicated that Artemisinin can selectively target and kill cancer cells while leaving healthy cells unharmed This unique trait has sparked interest in using Artemisinin as an alternative cancer treatment either alone or in combination with other therapies The development and production of Artemisinin have become critical in addressing the global burden of malaria and exploring its therapeutic potential in other diseases Efforts are being made to ensure the sustainable cultivation and extraction of Artemisinin as well as the development of costeffective methods for its production This will not only improve access to this lifesaving compound but also pave the way for further research and innovation in the field of medicine

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Is Larinate banned in India?

In India the availability of this particular medication necessitates a valid prescription from a medical professional This regulatory measure ensures that individuals only have access to the medication after consulting with a qualified doctor By requiring a prescription the Indian healthcare system aims to prioritize patient safety and prevent any potential misuse or abuse of the medication It also allows doctors to evaluate the patients condition and determine whether this specific medication is suitable for their needs This cautious approach helps to ensure that individuals receive appropriate treatment and minimizes the risk of adverse effects Therefore if someone in India requires this medication they must consult a doctor who will assess their medical history and current health status before prescribing it This process not only safeguards the wellbeing of patients but also upholds the ethical and legal standards set by the medical industry

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Is Falarcin banned in India?

In India the availability of the product you are referring to is limited to individuals who possess a valid prescription from a doctor This means that in order to obtain this particular product one must first consult with a qualified healthcare professional who will evaluate their condition and determine if the product is suitable for their specific needs Following the consultation if the doctor deems it appropriate they will provide a prescription which allows the individual to legally obtain the product from a pharmacy or authorized medical supplier This regulation ensures that the product is used responsibly and under the guidance of a medical professional in order to prioritize the safety and wellbeing of individuals in India It is important to abide by these guidelines and seek professional advice when considering the use of any medication or healthcare product Doing so ensures that individuals receive the appropriate treatment and support for their specific health concerns

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Is Genuate banned in India?

In India the availability of certain medications is regulated requiring a doctors prescription to obtain them This measure ensures the safety and appropriate usage of these drugs By implementing this system the government aims to protect the public from potential risks associated with selfmedication and inappropriate use of medications While this may seem inconvenient for some it is a necessary step to safeguard the health and wellbeing of individuals in the country Having a doctors prescription serves several purposes Firstly it helps to prevent the misuse or abuse of medications that can have severe consequences on ones health Secondly it allows medical professionals to evaluate the patients condition and history ensuring that the prescribed medication aligns with their specific needs Additionally prescriptions enable doctors to monitor the patients progress and make any necessary adjustments to the treatment plan The process of obtaining a prescription is relatively straightforward Individuals seeking medication must schedule an appointment with a qualified healthcare provider who will assess their medical condition and recommend appropriate treatment Following the consultation the doctor will issue a prescription that can be presented to a licensed pharmacist to obtain the prescribed medication This system ensures that individuals receive the appropriate treatment and minimizes the risks associated with selfdiagnosis and selfmedication

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Is T Nate banned in India?

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How does Artesar work?

The mechanism of action of this particular compound involves the production of free radicals which have the capacity to effectively target and eliminate the malarial parasite known as Plasmodium By generating these highly reactive molecules this substance is able to disrupt vital processes within the parasite ultimately leading to its demise The production of free radicals is a critical step in the chain of events that result in the destruction of the malarial parasite This compounds unique ability to generate these radicals distinguishes it as an effective weapon against the Plasmodium parasite offering a promising approach for combating malaria As the free radicals are unleashed they directly attack specific targets within the parasite such as key proteins or cell membranes interfering with essential biological processes Consequently the malarial parasite is unable to survive leading to its complete eradication This innovative mechanism of action places this compound at the forefront of antimalarial treatments showcasing its potential for contributing to the global efforts in controlling and ultimately eliminating malaria

Written By:

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Published At: Dec 10, 2024

Updated At: Dec 30, 2024

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Dec 30, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.