Larinate 120mg Injection
Larinate 120mg Injection
Introduction to Larinate 120mg Injection
Larinate 120mg Injection contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases. Belonging to the artemisinin class of medications holds a place on the World Health Organization's List of Essential Medicines.
It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA). This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins. Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels.
While generally well tolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels. In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported.
It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester. It is generally safe for use in children, with adjustments in dosing for those under 20 kg. Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin.
In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action. The timing and severity of the missed dose will be considered to determine the most suitable response.
Related Faqs
Where does Larinate come from?
Artemisinin is a naturally occurring compound that is derived from the Artemisinin tree scientifically known as Artemisia annua This plant also referred to as sweet wormwood or annual wormwood is native to Asia and has been used in traditional Chinese medicine for centuries Artemisinin is extracted from the leaves and flowers of the Artemisinin tree through a process called solvent extraction Artemisinin gained worldwide attention in the 1970s when Chinese researchers discovered its potent antimalarial properties Since then it has become an essential component in the treatment of malaria particularly in cases of drugresistant strains Artemisinin has shown remarkable effectiveness in reducing the parasite load in infected individuals and has played a significant role in saving countless lives Apart from its antimalarial properties Artemisinin has also shown potential in treating other diseases such as cancer Studies have indicated that Artemisinin can selectively target and kill cancer cells while leaving healthy cells unharmed This unique trait has sparked interest in using Artemisinin as an alternative cancer treatment either alone or in combination with other therapies The development and production of Artemisinin have become critical in addressing the global burden of malaria and exploring its therapeutic potential in other diseases Efforts are being made to ensure the sustainable cultivation and extraction of Artemisinin as well as the development of costeffective methods for its production This will not only improve access to this lifesaving compound but also pave the way for further research and innovation in the field of medicine
Is Larinate banned in India?
In India the availability of this particular medication necessitates a valid prescription from a medical professional This regulatory measure ensures that individuals only have access to the medication after consulting with a qualified doctor By requiring a prescription the Indian healthcare system aims to prioritize patient safety and prevent any potential misuse or abuse of the medication It also allows doctors to evaluate the patients condition and determine whether this specific medication is suitable for their needs This cautious approach helps to ensure that individuals receive appropriate treatment and minimizes the risk of adverse effects Therefore if someone in India requires this medication they must consult a doctor who will assess their medical history and current health status before prescribing it This process not only safeguards the wellbeing of patients but also upholds the ethical and legal standards set by the medical industry
How does Larinate work?
The mechanism of action of this compound involves the generation of highly reactive molecules known as free radicals which play a pivotal role in the elimination of the malarial parasite Plasmodium These free radicals possess an immense capacity to disrupt essential cellular components and metabolic processes within the parasite ultimately leading to its demise By introducing oxidative stress this compound renders the malarial parasite vulnerable and unable to survive within the host organism The production of free radicals occurs through a series of chemical reactions initiated by the compounds interaction with specific molecular targets within the parasite This process not only impairs the parasites ability to replicate and infect new cells but also facilitates the destruction of existing parasites Through this targeted mode of action the compound effectively combats malaria by directly attacking the parasite responsible for the disease By exploiting the susceptibility of Plasmodium to oxidative damage this compound represents a promising strategy for the development of new antimalarial treatments that could potentially alleviate the burden of this devastating disease worldwide
Where does Aisunate come from?
Derived from the Artemisinin tree this substance is highly sought after for its medicinal properties The Artemisinin tree also known as Sweet Wormwood or Qing Hao in Chinese is a plant native to Asia and has been used for centuries in traditional medicine The active compound extracted from this tree known as Artemisinin has been proven to be effective in treating malaria a deadly disease caused by parasites transmitted through mosquito bites Artemisinin is renowned for its powerful antimalarial properties as it targets and destroys the malaria parasites in the bloodstream This natural compound works by generating free radicals within the parasites causing irreversible damage to their cell membranes and ultimately leading to their death With the rise of drugresistant strains of malaria Artemisinin has become a crucial weapon in the fight against this global health crisis In addition to its antimalarial effects Artemisinin has also shown promise in treating other diseases such as cancer and inflammatory conditions Research has suggested that this natural compound has anticancer properties inhibiting the growth of cancer cells and inducing their death Furthermore it has been found to possess antiinflammatory and immunomodulatory effects making it a potential therapeutic agent for various inflammatory conditions including rheumatoid arthritis and inflammatory bowel disease Overall the remarkable properties of Artemisinin make it a valuable and versatile compound in the field of medicine With ongoing research and development this natural substance holds promise for the treatment of not only malaria but also other diseases afflicting humanity
Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.
Larinate 120mg Injection
Prescription Required
Packaging :
vial of 15 ml Injection
Manufacturer :
Ipca Laboratories LtdComposition :
Artesunate (120mg)MRP :
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