keygraf (TACROLIMUS)
Introduction to keygraf
Keygraf, also known as Tacrolimus, is a medication primarily used to prevent organ rejection in patients who have undergone organ transplants, such as kidney transplants. It wor... See More

What is Keygraf?
Keygraf is an immunosuppressant medication used to prevent organ rejection after a transplant. It works by suppressing the immune system to prevent it from attacking the transplanted organ. Keygraf is also used for other conditions like certain autoimmune diseases. It's important to take Keygraf exactly as prescribed and attend regular check-ups to monitor its effectiveness and any side effects. Your doctor will adjust your treatment based on your response and medical needs.

What is the usual dose of Keygraf?
The usual starting dose of Keygraf for adults varies based on the condition being treated and individual factors. It's typically taken twice daily. Your doctor will adjust the dose based on your response and blood levels. The maximum dose depends on your specific needs and medical condition. Children and elderly patients may require different dosing. Always follow your doctor's dosing instructions and attend regular check-ups to monitor your response to the medication.

How do I take Keygraf?
Take Keygraf exactly as your doctor prescribes. It's usually taken twice daily, in the morning and evening, on an empty stomach, either 1 hour before or 2 hours after meals. Do not crush or chew the capsules. If you miss a dose, take it as soon as you remember unless it's close to your next dose. In that case, skip the missed dose. Avoid grapefruit and grapefruit juice, as they can affect how Keygraf works. Always follow your doctor's specific instructions.

For how long do I take Keygraf?
Keygraf is usually a long-term medication for preventing organ rejection after a transplant. You'll typically take it every day as a lifelong treatment unless your doctor suggests otherwise. Stopping Keygraf without medical advice could cause your body to reject the transplanted organ. How long you'll need this medication depends on your body's response and any side effects you experience. Always talk with your doctor before changing or stopping your Keygraf treatment.

What disease or symptom is Keygraf used for?
Keygraf is primarily used to prevent organ rejection after a transplant. It helps the body accept the new organ by suppressing the immune system. Keygraf is also used for certain autoimmune diseases, where the immune system attacks the body's own tissues. It can be used alone or with other medications to enhance its effectiveness. Always follow your doctor's instructions and attend regular check-ups to monitor your response to Keygraf.

How long does it take for Keygraf to start working?
Keygraf starts working in your body shortly after you take it, but the full therapeutic effect may take several days to weeks. The time it takes to work can depend on individual factors like your condition and response to the medication. Regular blood tests will monitor Keygraf levels to ensure it's working effectively. It's important to take Keygraf exactly as prescribed and attend regular check-ups to monitor its effectiveness and any side effects.

Is Keygraf effective?
Keygraf is effective in preventing organ rejection after a transplant. It works by suppressing the immune system to prevent it from attacking the transplanted organ. Clinical studies show Keygraf significantly reduces the risk of organ rejection compared to other treatments. It's important to take Keygraf exactly as prescribed and attend regular check-ups to monitor its effectiveness. Your doctor will adjust your treatment based on your response and any side effects.

How do I know if Keygraf is working?
Keygraf is used to prevent organ rejection after a transplant. You'll know it's working if your body doesn't show signs of rejecting the transplanted organ. Regular blood tests will monitor Keygraf levels and organ function. Your doctor will check for signs of rejection, such as changes in organ function or symptoms like fever. Regular check-ups are important to ensure Keygraf is working effectively. Your doctor may adjust your treatment based on test results and how you're feeling.

How does Keygraf work?
Keygraf works by suppressing the immune system to prevent it from attacking a transplanted organ. It inhibits a protein called calcineurin, which is involved in activating immune cells. Think of it like turning down the volume on an overactive immune response. This helps prevent organ rejection after a transplant. Keygraf is effective in reducing the risk of rejection and is an important part of post-transplant care. Regular monitoring ensures its effectiveness and safety.

Who should avoid taking Keygraf?
Don't use Keygraf if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Keygraf is not recommended for people with certain kidney problems, as it can worsen kidney function. Caution is needed if you have high blood pressure or diabetes. Always consult your doctor about your medical history before starting Keygraf. They can determine if it's safe for you and monitor for any potential risks.

Can I take Keygraf with other prescription drugs?
Keygraf has several important drug interactions. It can interact with medications like certain antibiotics and antifungals, increasing the risk of side effects. Some drugs can reduce Keygraf's effectiveness, leading to organ rejection. Always inform your doctor about all medications you're taking. They can help manage interactions and adjust your treatment as needed. Regular blood tests may be necessary to monitor Keygraf levels and ensure safe and effective treatment.

Can Keygraf be taken safely while pregnant?
Keygraf should be used during pregnancy only if the benefits outweigh the risks. Limited data is available on its safety in pregnant women. Keygraf can cross the placenta, potentially affecting the baby. If you're pregnant or planning to become pregnant, talk with your doctor about the safest way to manage your condition. Your doctor can help create a treatment plan that protects both you and your baby.

Can Keygraf be taken safely while breastfeeding?
Keygraf is excreted into breast milk, and its effects on a breastfed infant are not well-studied. It may affect the baby's immune system. If you're breastfeeding or planning to breastfeed, discuss with your doctor whether to continue Keygraf. They can help weigh the benefits and risks and suggest safer alternatives if needed. Your doctor will guide you on the best approach to ensure your baby's safety.

Is Keygraf safe for the elderly?
Elderly patients are more vulnerable to the side effects of Keygraf, such as kidney problems and high blood pressure. They may require lower doses and closer monitoring. Keygraf can be used safely in the elderly with careful management. Regular check-ups and blood tests are important to monitor its effects. Always discuss any concerns with your doctor, who can adjust your treatment to minimize risks.

How should I store Keygraf?
Store Keygraf at room temperature, away from moisture and light. Keep it in a tightly closed container. Don't store it in humid places like bathrooms, as moisture can affect the medication. If your pills came in packaging that isn't child-resistant, transfer them to a container that children can't easily open. Always store Keygraf out of children's reach to prevent accidental swallowing. Check the expiration date regularly and properly dispose of any unused or expired medication.

Does Keygraf make people tired or drowsy?
Keygraf can cause fatigue or tiredness, but these effects are not common. If you notice you're feeling unusually tired while taking Keygraf, talk with your doctor. Your tiredness might be caused by something else, like another medication or an underlying health condition. Your doctor can help determine the cause and recommend adjustments to your treatment plan. Proper rest, regular physical activity, and a balanced diet can help maintain your energy levels.

Does Keygraf cause stomach upset?
Keygraf can cause stomach upset, including nausea, vomiting, or diarrhea. These side effects are not common. If you experience mild stomach upset, taking Keygraf with food might help. If symptoms persist or worsen, contact your doctor. They can determine if Keygraf is the cause and suggest ways to manage these side effects. Always inform your healthcare provider about any new or worsening symptoms.

Does Keygraf affect sleep?
Keygraf can cause sleep disturbances like insomnia, but these effects are not common. If you notice changes in your sleep patterns after starting Keygraf, talk with your doctor. Sleep problems might be related to Keygraf or another health condition. Your doctor can help determine the cause and suggest ways to improve your rest while continuing your treatment. It's important to address any sleep concerns with your healthcare provider.

Does Keygraf make it hard to think or concentrate?
Keygraf can cause cognitive side effects like difficulty concentrating or remembering, but these are not common. If you notice problems with your thinking, talk with your doctor. These symptoms might be related to Keygraf or another health condition. Your doctor can help determine the cause and suggest solutions while keeping your treatment plan on track. Don't stop taking Keygraf without consulting your doctor.

Does Keygraf affect mood?
Keygraf can affect mood, causing changes like anxiety or agitation, but these effects are rare. If you notice mood changes after starting Keygraf, talk with your doctor. These symptoms might be related to the medication or another health condition. Your doctor can help determine the cause and suggest appropriate support while continuing your treatment. It's important to address any mental health concerns with your healthcare provider.

Does Keygraf interfere with sexual function?
Keygraf can interfere with sexual function, causing side effects like erectile dysfunction or loss of libido. These effects are considered rare. If you experience changes in your sexual function while taking Keygraf, talk with your doctor. They can help determine if the medication is the cause and suggest ways to manage these side effects. It's important to address any concerns with your healthcare provider to ensure your treatment plan is effective and comfortable for you.

Does Keygraf affect appetite?
Keygraf can affect appetite, leading to changes in how hungry you feel, but these effects are not common. If you notice unexpected changes in your appetite, talk with your doctor. They can help determine if Keygraf is the cause and suggest ways to manage these changes. Maintaining regular meal times and a balanced diet can help manage appetite changes while taking Keygraf.

Does Keygraf cause weight gain?
Keygraf can cause weight changes, but these effects are not common. Some people may experience weight gain due to fluid retention or changes in appetite. If you notice significant weight changes, talk with your doctor. They can help determine if Keygraf is the cause and suggest ways to manage these changes. Maintaining a balanced diet and regular exercise can help manage weight while taking Keygraf.

Does Keygraf cause headaches?
Headaches can occur as a side effect of Keygraf, but they are not common. If you experience mild headaches, staying hydrated and resting may help. Over-the-counter pain relievers can be used after consulting your doctor. If headaches are severe or persistent, contact your healthcare provider. They can determine if Keygraf is the cause and suggest appropriate management strategies.

Does Keygraf limit driving?
Keygraf can cause side effects like dizziness or blurred vision, which may impair your ability to drive. Avoid driving until you know how Keygraf affects you. If you feel dizzy or have vision changes, don't drive until these symptoms go away. Always pay attention to how your body responds to Keygraf, especially when you first start taking it. Talk with your doctor if you have concerns about driving safely.

Is it safe to drink alcohol while taking Keygraf?
It's best to avoid alcohol while taking Keygraf. Alcohol can increase the risk of liver damage and affect how Keygraf works. It may also worsen side effects like dizziness or nausea. If you choose to drink occasionally, limit your alcohol intake and watch for warning signs like unusual tiredness or stomach pain. Talk with your doctor about alcohol use while taking Keygraf to get personalized advice based on your health situation.

Is it safe to drink coffee or tea while taking Keygraf?
You can drink coffee and tea while taking Keygraf, but moderation is key. Caffeine can increase blood pressure, which Keygraf may also affect. Both Keygraf and caffeine can cause dehydration, so drink plenty of water. If you notice symptoms like dizziness or increased heart rate, talk with your doctor. They can provide guidance on caffeine consumption while taking Keygraf to ensure your treatment is safe and effective.

Is it safe to exercise while taking Keygraf?
You can exercise while taking Keygraf, but be cautious. Keygraf can cause side effects like high blood pressure or dizziness, which might affect your exercise capacity. Stay hydrated and avoid strenuous activities if you feel unwell. Listen to your body and rest if needed. Most people can maintain their regular exercise routine, but check with your doctor if you have concerns about your specific situation.

What are Keygraf possible harms and risks?
Keygraf can cause common problems like diarrhea, constipation, nausea, swelling, and shaking. More serious, but less common, problems include kidney issues, nervous system problems (like confusion, numbness, or seizures), high blood pressure, high blood sugar, high potassium, and blood clotting problems. A fruity breath smell with nausea, vomiting, or stomach pain is a serious warning sign.
Available in 3 variations

Keygraf 1 Capsule
Keygraf 1 Capsule
Tacrolimus (1mg)
strip of 10 capsules

Keygraf 2 Capsule
Keygraf 2 Capsule
Tacrolimus (2mg)
strip of 10 capsules

Keygraf 0.5mg Capsule 10s
Keygraf 0.5mg Capsule 10s
Tacrolimus (0.5mg)
strip of 10 capsules