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Karat 50mg Tablet contains Artesunate, which is a medication primarily utilized for the treatment of malaria, particularly in severe cases Belonging to the artemisinin class of medications,holds a place on the World Health Organization''s List of Essential Medicines

It functions as a prodrug, rapidly converting to its active form, dihydroartemisinin (DHA) This transformation generates reactive oxygen species, inducing oxidative stress and causing damage to malarial proteins Additionally, it inhibits the essential Plasmodium falciparum exported protein 1 (EXP1), reducing parasite glutathione levels

 

While generally welltolerated, common side effects may include a slow heartbeat, allergic reactions, dizziness, and low white blood cell levels In severe cases, kidney failure requiring dialysis, hemoglobinuria (presence of hemoglobin in urine), and jaundice have been reported

 

It is considered safe during pregnancy, particularly in the second and third trimesters, although caution is advised in the first trimester It is generally safe for use in children, with adjustments in dosing for those under 20 kg Notably, it should be avoided in newborns when combined with sulfadoxine/pyrimethamine due to potential effects on bilirubin

 

In the event of a missed dose, it is crucial to consult with a healthcare professional for guidance on the appropriate course of action The timing and severity of the missed dose will be considered to determine the most suitable response

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Available in 2 variations

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Karat 60mg Injection

Karat 60mg Injection

Artesunate (60mg)

vial of 1 Powder for Injection

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Karat 50mg Tablet

Karat 50mg Tablet

Artesunate (50mg)

strip of 4 tablets

Related Faqs

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Is Malart banned in India?

In India the accessibility of certain medications is strictly controlled and monitored One such medicine requiring a doctors prescription is available exclusively through this regulated process This practice aims to ensure the safety and wellbeing of individuals by preventing the misuse or improper administration of potentially harmful drugs By implementing these restrictions the government and medical authorities aim to minimize the risks associated with selfmedication and encourage individuals to consult a healthcare professional for proper diagnosis and prescription This system plays a crucial role in safeguarding public health and upholding ethical standards in the pharmaceutical industry Therefore if one wishes to obtain this particular medicine in India it is essential to consult a qualified doctor who can assess the individuals condition and prescribe the appropriate treatment By following this established protocol individuals can receive the necessary medication while also prioritizing their health and wellbeing

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How does Falcimax work?

The mechanism of action involves the generation of reactive molecules known as free radicals which effectively eradicate the malarial parasite specifically Plasmodium These free radicals have the ability to disrupt vital cellular processes within the parasite leading to its ultimate demise By generating these highly reactive species the drug displays a targeted approach to combating malaria ensuring that the parasite is specifically targeted while minimizing harm to the host organism This unique mode of action sets it apart from other antimalarial medications making it an effective and valuable tool in the fight against malaria The production of free radicals effectively harnesses the oxidative power of the drug allowing it to selectively destroy Plasmodium and halt the progression of the disease By attacking the parasite at its core this drug offers a promising approach to malaria treatment and prevention and continues to play a pivotal role in global efforts to control this devastating disease

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How does Falno work?

The mechanism of action involves the generation of free radicals which effectively eradicates the malarial parasite known as Plasmodium This process plays a crucial role in combating the harmful effects of malaria By producing these highly reactive molecules the medication targets the parasite and disrupts its vital functions leading to its eventual demise These free radicals possess a remarkable ability to destroy the intricate structure of the Plasmodium parasite effectively neutralizing its growth and reproduction This innovative mode of action ensures the elimination of the parasite thereby alleviating the symptoms of malaria and preventing its further progression The selective action of this medication on the malarial parasite guarantees a targeted approach maximizing the efficacy of treatment and minimizing potential side effects Ultimately through the generation of free radicals this drug demonstrates its effectiveness in eradicating the Plasmodium parasite offering hope to those afflicted with malaria and contributing to the global efforts in combating this widespread and devastating disease

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How does Karat work?

This mechanism of action involves the generation of free radicals that effectively eliminate the malarial parasite also known as Plasmodium By inducing the production of these highly reactive molecules this process directly targets the parasite and disrupts its vital cellular functions The free radicals act by damaging the parasites cellular components including proteins lipids and nucleic acids ultimately leading to its death and preventing further spreading of the infection Through this targeted approach the generation of free radicals serves as an effective strategy to combat malaria By selectively attacking the parasite while minimizing damage to the hosts cells this mechanism offers a promising way to treat the disease This method also helps to reduce the risk of resistance development as it directly affects the parasites specific biological pathways essential for its survival Furthermore this approach takes advantage of the parasites vulnerability to oxidative stress The release of free radicals overwhelms the antioxidant defenses of the malarial parasite rendering it unable to neutralize the excessive reactive oxygen species As a result the accumulation of oxidative damage becomes lethal to the parasite effectively eradicating the infection In summary the production of free radicals presents a unique and efficient mechanism in the fight against malaria By selectively targeting the parasite and disrupting its vital cellular processes this method offers a promising avenue for the development of novel antimalarial treatments

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Is Alpasunate banned in India?

No in India this particular medication can only be obtained with a valid prescription from a licensed doctor It is not available overthecounter and cannot be purchased without proper authorization from a healthcare professional This regulation is in place to ensure the safe and responsible use of the medication as it may carry potential risks and side effects that need to be carefully considered by a qualified medical practitioner Purchasing medications without a prescription can pose serious health hazards and is generally discouraged Thus it is important to consult with a doctor who can assess your specific medical condition review your medical history and provide the necessary guidance on whether this medication is suitable for you Remember your health and wellbeing are of utmost importance and it is always best to follow the advice and recommendations of healthcare professionals to ensure the safe and effective management of your medical needs

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Is T Nate banned in India?

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Published At: Dec 10, 2024

Updated At: Dec 30, 2024

Reviewed By:

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Published At: Dec 10, 2024

Updated At: Dec 30, 2024

Disclaimer : This information is not a substitute for medical advice. Consult your healthcare provider before making any changes to your treatment . Do not ignore or delay professional medical advice based on anything you have seen or read on Medwiki.