The Junimol RDS 170mg Suppository is specifically designed for rectal use and should not be used in any other way It is important to follow your doctors instructions regarding the dosage and duration of treatment The medication typically begins to take effect within one hour If you are taking any other medications containing paracetamol it is crucial to inform your doctor to avoid overdosing To ensure optimal absorption it is recommended to avoid having a bowel movement after administration There are potential side effects associated with rectal administration such as nausea constipation itching and black stools If you experience any rash or allergic reaction while taking this medicine it is important to inform your doctor immediately Pregnant and nursing women should only use this medication under the supervision of a healthcare professional It is also important to exercise caution in patients with liver and kidney disease or those with a history of alcohol abuse It is not recommended for patients with severe or active liver disease